You are here: Home> Turkey>TR-REACH>EC 921-577-3> EC 921-577-3 | Data Package 100 - 1000 t/a (Affiliates of HCSC Consortium members)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of vapour pressures and heats of vapourisation of hydrocarbons and related compounds | Author: Zwolinski B.J and Wilhoit R.C | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Henry's law constant | Robust Study Summary -- Title: HENRYWIN v3.20 | Author: US EPA | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Water solubility | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Phys-Chem | Water solubility | Robust Study Summary -- Title: Solubility in water of Paraffin, Cycloparaffin, Olefin, Acetylene, Cycloolefin, and Aromatic Hydrocarbons | Author: McAuliffe C. | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Phys-Chem | Water solubility | Robust Study Summary -- Title: Solubility in water of Paraffin, Cycloparaffin, Olefin, Acetylene, Cycloolefin, and Aromatic Hydrocarbons | Author: McAuliffe C. | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Water solubility | Robust Study Summary -- Title: Solubility in water of Paraffin, Cycloparaffin, Olefin, Acetylene, Cycloolefin, and Aromatic Hydrocarbons. | Author: McAuliffe C. | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Isopentane: Determination of Partition Coefficient (n-Octanol/Water) | Author: Harlan Laboratories Ltd. | Year: 2014 | Guideline: 117 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Viscosity | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Viscosity | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Flammability | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Flammability | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Flash point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Flash point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary dermal irritation study in the rabbit | Author: Trimmer G.W. | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary dermal irritation study in the rabbit | Author: Trimmer G.W. | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Eye irritation | Robust Study Summary -- Title: Ocular irritation study in the rabbit without eyewash with n-pentane | Author: Frank E.R. | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Eye irritation | Right to refer to study -- Title: Ocular irritation study in the rabbit without eyewash with n-pentane | Author: Frank E.R. | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.W. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.W. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.I. Phillips R.D. and Letinski D.J. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Toxicological | Skin sensitisation | Right to refer to study -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.I. Phillips R.D. and Letinski D.J. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: In vitro microbiological mutagenicity studies of hydrocarbon propellants | Author: Kirwin C.J. Thomas W.C. Simmon V.F. | Year: 1980 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro chromosomal aberration assay in Chinese hamster ovary (CHO) cells - modified for volatile test materials | Author: Pryzgoda R.T. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro chromosomal aberration assay in Chinese hamster ovary (CHO) cells - modified for volatile test materials | Author: Pryzgoda R.T. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Assessment of the genotoxic potential of unleaded gasoline and 2,2,4-trimethylpentane in human lymphoblasts in vitro. | Author: Richardson K. et al. | Year: 1986 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 540-84-1 | EC 208-759-1 | 2,2,4-trimethylpentane) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity study in the rat with n-pentane | Author: Frank E.R. | Year: 1996 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity study in the rat with n-pentane | Author: Frank E.R. | Year: 1996 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity study in rats. Cyclopentane. | Author: Pence D.H. | Year: 1982 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity study in rats. Cyclopentane. | Author: Pence D.H. | Year: 1982 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Relative acute neurotoxicity of solvents: Isoeffective air concentrations of 48 compounds evaluated in rats and mice | Author: Frantik E., Hornychova and M. Horvath M. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Cyclopentane acute inhalation toxicity in rats 4-hour exposure | Author: Jackson G.C. | Year: 1993 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Cyclopentane acute inhalation toxicity in rats 4-hour exposure | Author: Jackson G.C. | Year: 1993 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Study on the inhalation kinetics of cyclopentane in rats | Author: Filser J.G. | Year: 1997 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism of ethane and pentane to carbon dioxide by the rat | Author: Daugherty M.S., Ludden T.M. And Burk R.F. | Year: 1988 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Uptake of 19 hydrocarbon vapors inhaled by F344 rats | Author: Dahl A.R. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Repeated exposure inhalation study of pentane in rats | Author: Stadler J.C. et al. | Year: 2001 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The effects of short-term inhalatory exposure to isopentane on behavior in the rat | Author: Lammers J.H.C.M. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The effects of short-term inhalatory exposure to isopentane on behavior in the rat | Author: Lammers J.H.C.M. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The effects of short-term inhalatory exposure to n-pentane on behavior in the rat | Author: Lammers J.H.C.M. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The effects of short-term inhalatory exposure to n-pentane on behavior in the rat | Author: Lammers J.H.C.M. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Cyclopentane-Subchronic inhalation toxicity and neurotoxicity study in Wistar rats 90-day vapor exposure | Author: Gamer A.O. | Year: 1998 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicity evaluation of petroleum blending streams: Inhalation subchronic toxicity/neurotoxicity study of a light alkylate naphtha distillate in rats | Author: Schreiner C. et al. | Year: 1998 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 64741-66-8) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: 90-Day subchronic inhalation toxicity study in the rat with n-pentane | Author: Whitman F.T. | Year: 1997 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: 90-Day subchronic inhalation toxicity study in the rat with n-pentane | Author: Whitman F.T. | Year: 1997 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 12 week inhalation toxicity study of MRD-78-26 in the rat | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (Hydrocarbons, C7-C9 isoalkanes) |
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| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 12 week inhalation toxicity study of MRD-78-26 in the rat | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (Hydrocarbons, C7-C9 isoalkanes) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Absence of hydrocarbon-induced nephropathy in rats exposed subchronically to volatile hydrocarbon mixtures pertinent to gasoline | Author: Aranyi C. et al. | Year: 1986 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (n-isobutane,:n-isopentane) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Experimental neurotoxicity and urinary metabolites of the C5-C7 aliphatic hydrocarbons used as glue solvents in shoe manufacture | Author: Frontali N. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Inhalation developmental toxicity and reproduction studies with cyclohexane | Author: Kreckmann K.H. et al. | Year: 2000 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 110-82-7 | EC 203-806-2 | cyclohexane) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity study in rats with n-pentane | Author: Trimmer G.W. | Year: 1997 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Developmental toxicity study in rats with n-pentane | Author: Trimmer G.W. | Year: 1997 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: A segment II teratology study in rats following inhalation exposure to MRD-78-25 and MRD-78-26. Final report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (Hydrocarbons, C7-C9 isoalkanes) |
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| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: A segment II teratology study in rats following inhalation exposure to MRD-78-25 and MRD-78-26. Final report | Author: ExxonMobil Petroleum & Chemical BVBA | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. Read-Across (Hydrocarbons, C7-C9 isoalkanes) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: One-generation reproductive toxicity study of 2-methylbutane in Sprague-Dawley rats | Author: Yu Wook-Joon et al. | Year: 2011 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Inhalation developmental toxicity and reproduction studies with cyclohexane | Author: Kreckmann K.H. et al. | Year: 2000 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 110-82-7 | EC 203-806-2 | Cyclohexane) |
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| Toxicological | Neurotoxicity | Robust Study Summary -- Title: The relative anaesthetic activity of the butanes and pentanes | Author: Stoughton R. And Lamson P. | Year: 1936 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Toxicological | Neurotoxicity | Robust Study Summary -- Title: Cyclopentane-Subchronic inhalation toxicity and neurotoxicity study in Wistar rats 90-day vapor exposure. | Author: Gamer A.O. | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Toxicological | Neurotoxicity | Robust Study Summary -- Title: Toxicity evaluation of petroleum blending streams: Inhalation subchronic toxicity/neurotoxicity study of a light alkylate naphtha distillate in rats | Author: Schreiner C. et al. | Year: 1998 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 64741-66-8) |
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| Toxicological | Neurotoxicity | Robust Study Summary -- Title: A comparative study on the neurotoxicity of n-pentane, n-hexane, and n-heptane in the rat | Author: Takeuchi Y. et al. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 109-66-0 | EC 203-692-4 | n-pentane; pentane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: ECOWIN v1 ECOSAR Classes for Microsoft Windows | Author: Nabholz V and Mayo-Bean K | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 287-92-3 | EC 206-016-6 | cyclopentane) |
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| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute fish toxicity test rainbow trout renewal. | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute fish toxicity test rainbow trout renewal. | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic toxicity of compounds that may be carried by ships (MARPOL 1973 Annex II). A progress report for 1986 | Author: Adema D.M.M and van den Bos Baker G.H. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic toxicity of compounds that may be carried by ships (MARPOL 1973 Annex II). A progress report for 1986 | Author: Adema D.M.M and van den Bos Bakker G.H. | Year: 1987 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 78-78-4 | EC 201-142-8 | isopentane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Algal inhibition test | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Algal inhibition test | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: BCFBAF v3.01 | Author: No author provided | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman A.D. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath J.A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman A.D. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: Re-evaluation of target lipid model-derived HC5 predictions for hydrocarbons | Author: McGrath J.A. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Robust Study Summary -- Title: PETROTOX: An aquatic toxicity model for petroleum substances | Author: Redman A.D. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Mechanism and Structure | Author: Gould E. | Year: 1959 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Chapter 7: Rate of Hydrolysis | Author: Harris J. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis | Author: Neely W. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Readily biodegradability: OECD 301F Manometric respirometry test: N-pentane | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Readily biodegradability: OECD 301F Manometric respirometry test: N-pentane | Author: ExxonMobil Chemical | Year: 1997 | Guideline: 301 F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. Read-Across (CAS 109-66-0 | EC 203-692-4 | pentane) |
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| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ready biodegradability: 'manometric respirometry test' | Author: ExxonMobil Chemical | Year: 1996 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ready biodegradability: 'manometric respirometry test' | Author: ExxonMobil Chemical | Year: 1996 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. Read-Across (CAS 78-78-4 | EC 201-142-8 | 2-methylbutane) |
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| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Prediction of the Sorption of Organic Compounds into Soil Organic Matter from Molecular Structure | Author: Schüürmann et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |