You are here: Home> Taiwan>TW-REACH>CAS 98-83-9> CAS 98-83-9 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Sicherheitsdatenblatt gemaess 91/155/EWG - Alphamethylstyrol (AMS) vom September 2001 | Author: INEOS Phenol GmbH & Co. KG | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Sicherheitsdatenblatt gemaess 91/155/EWG - Alphamethylstyrol (AMS) vom September 2001 | Author: INEOS Phenol GmbH & Co. KG | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Occupational health guideline for α-methylstyrene. | Author: NIOSH | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Supplements to the sixth edition. Documentation of the threshold limit values and biological exposure indices - α-methylstyrene. | Author: ACGIH | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. A ready-reference book of chemical and physical data. | Author: Lide DR & Frederikse HPR (ed.) | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Styrene. | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Alpha-methylstyrene. | Author: Ullmann | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. A ready-reference book of chemical and physical data. | Author: Lide DR & Frederikse HPR (ed.) | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Styrene. | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Alpha-Methylstyrene. | Author: Ullmann | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. A ready-reference book of chemical and physical data. | Author: Lide DR & Frederikse HPR (ed.) | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Styrene | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Alpha-methylstyrene. | Author: Ullmann | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Styrene | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Alpha-methylstyrene. | Author: HSDB | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. 84th ed. (2003-2004). | Author: Lide DR (ed.) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. A ready-reference book of chemical and physical data. | Author: Lide DR & Frederikse HPR (ed.) | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Exploring QSAR - Hydrophobic electronic and steric constants. | Author: Hansch C Leo A and Hoekman D | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Calculation of environmental fate parameters of α-methylstyrene using EPIWIN v3.11. | Author: Fh-ITEM | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Calculation of environmental fate parameters of α-methylstyrene using EPIWIN v3.11. | Author: Fh-ITEM | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: (1-Methylethenyl)benzene | Author: MITI (Japan) | Year: 1997 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: (1-Methylethenyl)benzene | Author: MITI (Japan) | Year: 1997 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Alpha-methylstyrene | Author: SRC | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: No information | Author: HSDB | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Solubility in organic solvents/fat solubility | Robust Study Summary -- Title: Styrene. | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: CRC Handbook of chemistry and physics. | Author: Lide DR (ed.) | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Styrene. | Author: Kirk-Othmer | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Alpha-methylstyrene. | Author: Ullmann | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: No information | Author: MITI Japan | Year: 1997 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Study on the 'ready biodegradability' of αmethylstyrene according to C.4-E of the EU Regulation 440/2008 dated 30th May 2008 and according to OECD-Test Guideline 301 D Version dated 17th July 1992 (Closed-Bottle-Test) | Author: P&D REACH Consortium | Year: 2009 | Guideline: 301D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Study on the 'ready biodegradability' of αmethylstyrene according to C.4-E of the EU Regulation 440/2008 dated 30th May 2008 and according to OECD-Test Guideline 301 D Version dated 17th July 1992 (Closed-Bottle-Test) | Author: P&D REACH Consortium | Year: 2009 | Guideline: 301D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Study on the 'inherent biodegradability' of αmethylstyrene according to OECD-Test Guideline 302 C in the Version dated 12.05.1981 (Modified MITI-Test (II)) | Author: P&D REACH Consortium | Year: 2010 | Guideline: 302C | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Study on the 'inherent biodegradability' of αmethylstyrene according to OECD-Test Guideline 302 C in the Version dated 12.05.1981 (Modified MITI-Test (II)) | Author: P&D REACH Consortium | Year: 2010 | Guideline: 302C | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and bioaccumulation - Data of existing chemicals based on the CSCL Japan. | Author: MITI | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 98-86-2 | EC 202-708-7 | 1-phenylethanone) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Brine shrimp bioassay and seawater BOD of petrochemicals. | Author: Price KS, Waggy GT, Conway RA | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 98-82-8 | EC 202-704-5 | isopropylbenzene) |
- |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Microbial metabolism and biotransformation of styrene. | Author: Warhurst AM & Fewson CA | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan. | Author: MITI | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law. - Alpha-Methylstyrene | Author: NITE | Year: 2008 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: 2-Phenylpropene - Adsorption coefficient C.19 (OECD 121) Koc (HPLC-Method). | Author: P&D REACH Consortium | Year: 2009 | Guideline: 121 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: 2-Phenylpropene - Adsorption coefficient C.19 (OECD 121) Koc (HPLC-Method). | Author: P&D REACH Consortium | Year: 2009 | Guideline: 121 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Calculation of environmental fate parameters of α-methylstyrene using EPIWIN v3.11 | Author: Fh-ITEM | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Calculation of environmental fate parameters of α-methylstyrene using EPIWIN v3.11 | Author: Fh-ITEM | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Study on the acute toxicity towards fish of α-methylstyrene according to C.1 Fish acute Toxicity Test of the Regulation 440/2008 dated 30-May-08 and OECD-Test Guideline No. 203 (1992) | Author: P&D REACH Consortium | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Study on the acute toxicity towards fish of α-methylstyrene according to C.1 Fish acute Toxicity Test of the Regulation 440/2008 dated 30-May-08 and OECD-Test Guideline No. 203 (1992) | Author: P&D REACH Consortium | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: not available in English | Author: MOE (Japan) | Year: 1997 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: not available in English | Author: MOE (Japan) | Year: 1997 | Guideline: 204 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Study on the acute toxicity towards Daphnia of α-methylstyrene according to OECD-Test Guideline No. 202 (Version dated 13. April 2004) and 67/548/EWG Appendix V C.2 | Author: P&D REACH Consortium | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Study on the acute toxicity towards Daphnia of α-methylstyrene according to OECD-Test Guideline No. 202 (Version dated 13. April 2004) and 67/548/EWG Appendix V C.2 | Author: P&D REACH Consortium | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: not available in English | Author: MOE (Japan) | Year: 1997 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: not available in English | Author: MOE (Japan) | Year: 1997 | Guideline: 211 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Study on the 'toxicity towards algae' of α-methylstyrene according to C.3 Algal InhibitionTest of the EU-Regulation 440/2008 dated 30 May 2008 and according to OECD-Test Guideline No. 201 in the Version dated 23 March 2006 | Author: P&D REACH Consortium | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Study on the 'toxicity towards algae' of α-methylstyrene according to C.3 Algal InhibitionTest of the EU-Regulation 440/2008 dated 30 May 2008 and according to OECD-Test Guideline No. 201 in the Version dated 23 March 2006 | Author: P&D REACH Consortium | Year: 2010 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: not available in English | Author: MOE (Japan) | Year: 1997 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Study on the toxicity towards bacteria of αmethylstyrene according to C.11 Biodegradation - Activated sludge respiration inhibition test of the EU-Regulation 440/2008 dated 30 May 2008 and according to OECD-Guideline No. 209 Version dated 04.04.1984 | Author: P&D REACH Consortium | Year: 2009 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Study on the toxicity towards bacteria of αmethylstyrene according to C.11 Biodegradation - Activated sludge respiration inhibition test of the EU-Regulation 440/2008 dated 30 May 2008 and according to OECD-Guideline No. 209 Version dated 04.04.1984 | Author: P&D REACH Consortium | Year: 2009 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and disposition of α-methylstyrene in rats | Author: De Costa et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toxicological studies of certain alkylated benzenes and benzene. Experiments on laboratory animals. | Author: Wolf MA et al. | Year: 1956 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Alpha-Methylstyrene. Range finding toxicity studies. | Author: Union Carbide Corp. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Initial submission: Toxicological investigation of: Alpha methyl styrene with cover letter dated 081392. | Author: Monsanto Co. | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Alpha-Methylstyrene. Range finding toxicity studies. | Author: Union Carbide Corp. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Alpha-Methylstyrene. Range finding toxicity studies. | Author: Union Carbide Corp. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Alpha-Methylstyrene. Range finding toxicity studies. | Author: Union Carbide Corp. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Skin irritation in rabbits after application of refined adiponitrile and crude α-methyl styrene with cover letter dated 072787. | Author: Monsanto Co. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Alpha-Methylstyrene. Range finding toxicity studies. | Author: Union Carbide Corp. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined repeat dose and reproductive/developmental toxicity screening test of 1-methylethenylbenzene by oral administration in rats | Author: Ministry of Health and Welfare (Japan) | Year: 1997 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Characterization of inhaled α-methylstyrene vapor toxicity for B6C3F1 mice and F344 rats. | Author: Morgan DL | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicological studies of certain alkylated benzenes and benzene. Experiments on laboratory animals. | Author: Wolf MA | Year: 1956 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Reverse Mutation test of 1-Methylethenylbenzene on bacteria. | Author: Ministry of Health and Welfare (Japan) | Year: 1997 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity test. V. Results from testing of 311 chemicals. | Author: Zeiger E et al. | Year: 1992 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Letter from Amoco Corporation to USEPA submitting enclosed final reports concerning 1-methylethylbenzene (α methyl styrene) with attachments | Author: Amoco Co. | Year: 1991 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenitaetsuntersuchung von α-Methylstyrol mit Hilfe des Salmonella typhimurium/Mikrosomen-Mutagenitaets-Tests nach Ames. | Author: Huels AG | Year: 1989 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenitaetsuntersuchung von α-Methylstyrol mit Hilfe des Salmonella typhimurium/Mikrosomen-Mutagenitaets-Tests nach Ames. | Author: Huels AG | Year: 1989 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In Vitro Chromosomal Aberration Test of 1-Methylethenylbenzene on Cultured Chinese Hamster Cells. | Author: Ministry of Health and Welfare (Japan) | Year: 1997 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Letter from Amoco Corporation to USEPA submitting enclosed final reports concerning 1-methylethylbenzene (α methyl styrene) with attachments | Author: Amoco Co. | Year: 1991 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Letter from Amoco Corporation to USEPA submitting enclosed final reports concerning 1-methylethylbenzene (α methyl styrene) with attachments | Author: Amoco Co. | Year: 1991 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of α-Methylstyrene (CAS NO. 98-83-9) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 2007 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined repeat dose and reproductive/developmental toxicity screening test of 1-methylethenylbenzene by oral administration in rats | Author: Ministry of Health and Welfare (Japan) | Year: 1997 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |