You are here: Home> Turkey>TR-REACH>CAS 98-13-5> CAS 98-13-5 | Data Package 100 - 1000 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal Developmental Toxicity Study after Repeated Oral Administration in Wistar Rats with Triethoxyphenylsilane (CAS RN 780-69-8) | Author: BSL Bioservice Scientific Laboratories | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal Developmental Toxicity Study after Repeated Oral Administration in Wistar Rats with Triethoxyphenylsilane (CAS RN 780-69-8) | Author: BSL Bioservice Scientific Laboratories | Year: 2020 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Waiver | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Repeated Inhalation Studies on Ethyl Silicate and Summary of Range Finding Data on Other Silanes | Author: Mellon Institute of Industrial Research | Year: 1951 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Trichloro(phenyl)silane: Acute toxicity to rainbow trout (Oncorhynchus mykiss) under static conditions. | Author: Springborn Smithers | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Trichloro(phenyl)silane: Acute toxicity to rainbow trout (Oncorhynchus mykiss) under static conditions. | Author: Springborn Smithers | Year: 2010 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Trichloro(phenyl)silane: Acute toxicity to water fleas (Daphnia magna) under static conditions. | Author: Springborn Smithers | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Trichloro(phenyl)silane: Acute toxicity to water fleas (Daphnia magna) under static conditions. | Author: Springborn Smithers | Year: 2010 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Trichloro(phenyl)silane: Growth inhibition test with Pseudokirchneriella subcapitata (syn. Selenastrum capricornutum) under static conditions | Author: Springborn Smithers | Year: 2009 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Trichloro(phenyl)silane: Growth inhibition test with Pseudokirchneriella subcapitata (syn. Selenastrum capricornutum) under static conditions | Author: Springborn Smithers | Year: 2009 | Guideline: 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Waiver | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Guideline: 107 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Guideline: 107 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: 90-day inhalation toxicity study of hydrogen chloride gas in B6C3F1 mice, Sprague-Dawley rats and Fischer-344 rats. | Author: Toxigenics Inc. | Year: 1984 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. Read-Across (CAS 7647-01-0 | EC 231-595-7 | Hydrogen chloride) |
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| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Stability: Dissociation constant | Waiver | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates | Author: Dow Corning Corporation | Year: 1998 | Guideline: ASTM E659 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates | Author: Dow Corning Corporation | Year: 1998 | Guideline: ASTM E659 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Flammability | Waiver | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: A 14-day repeated dose inhalation toxicity study with dow corning X2-2614 in albino rats | Author: Dow Corning Corporation | Year: 1991 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: yes. | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: A 14-day repeated dose inhalation toxicity study with dow corning X2-2614 in albino rats | Author: Dow Corning Corporation | Year: 1991 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: yes. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Screening tests on the hydrolysis of phenyl-trichlorosilane | Author: Evonik Goldschmidt | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Screening tests on the hydrolysis of phenyl-trichlorosilane | Author: Evonik Goldschmidt | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Environmental | Biodegradation in soil | Waiver | - |
| Phys-Chem | Surface tension | Waiver | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Vapor Pressures of Silicon Compounds | Author: Jenkins A. C., Chambers G. F. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: The AIChE DIPPR 801 Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Repeated Inhalation Studies on Ethyl Silicate and Summary of Range Finding Data on Other Silanes | Author: Mellon Institute of Industrial Research | Year: 1951 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Phys-Chem | Stability in organic solvents and identity of relevant degradation products | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates | Author: Dow Corning Corporation | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Flash Point, Autoignition Temperature, and Lower and Upper Flammability Limits of Selected Silicon Intermediates | Author: Dow Corning Corporation | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Repeated Inhalation Studies of Ethyl Silicate and Summary of Range Finding Data on other Silanes | Author: Mellon Institute of Industrial Research | Year: 1951 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Assessment of ready biodegradability; CO2 in sealed vessels (CO2 headspace test) | Author: Harlan Laboratories | Year: 2009 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Assessment of ready biodegradability; CO2 in sealed vessels (CO2 headspace test) | Author: Harlan Laboratories | Year: 2009 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Phenylsilanetriol (hydrolysis product of trichloro(phenyl)silane: assessment of the inhibitory effect on the respiration of activated sewage sludge | Author: Clarke N. | Year: 2008 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Phenylsilanetriol (hydrolysis product of trichloro(phenyl)silane: assessment of the inhibitory effect on the respiration of activated sewage sludge | Author: Clarke N. | Year: 2008 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Waiver | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Analytical Report Determination of Physico-chemical Properties of WACKER® SILAN P CAS No. 98-13-5 | Author: Wacker Chemie AG | Year: 2021 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Analytical Report Determination of Physico-chemical Properties of WACKER® SILAN P CAS No. 98-13-5 | Author: Wacker Chemie AG | Year: 2021 | Guideline: 109 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Repeated Inhalation Studies on Ethyl Silicate and Summary of Range Finding Data on Other Silanes | Author: Mellon Institute of Industrial Research | Year: 1951 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Waiver | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Analytical Report Determination of Physico-chemical Properties of WACKER® SILAN P, CAS No. 98-13-5 | Author: Wacker Chemie AG | Year: 2021 | Guideline: DIN 51562 Part 1 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Analytical Report Determination of Physico-chemical Properties of WACKER® SILAN P, CAS No. 98-13-5 | Author: Wacker Chemie AG | Year: 2021 | Guideline: DIN 51562 Part 1 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: no. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: The AIChE DIPPR 801 Database | Author: Design Institute for Physical Property Data (DIPPR) | Year: 1965 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Genetic Evaluation of Dow Corning Z-1216 Silane in Bacterial Reverse Mutation Assays | Author: Dow Corning Corporation | Year: 1985 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: yes. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Genetic Evaluation of Dow Corning Z-1216 Silane in Bacterial Reverse Mutation Assays | Author: Dow Corning Corporation | Year: 1985 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: yes. | - |
| Phys-Chem | Explosive properties | Waiver | - |
| Eco-Tox | Toxicity to soil microorganisms | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: No information | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: No information | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor Pressures of Silicon Compounds | Author: Jenkins A. C., Chambers G. F. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: no. | - |
| Toxicological | Eye irritation | Waiver | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro Chromosome Aberration Test in Chinese Hamster V79 Cells with Trimethoxyphenylsilane | Author: RCC Cytotest Cell Research | Year: 2008 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro Chromosome Aberration Test in Chinese Hamster V79 Cells with Trimethoxyphenylsilane | Author: RCC Cytotest Cell Research | Year: 2008 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Title: Phenylsilanetriol: Determination of partition coefficient and dissociation constant | Author: SafePharm Laboratories | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Toxicological | Acute toxicity: dermal | Waiver | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Design Institute for Physical Property Data | Author: DIPPR | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: not specified. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Prenatal Developmental Toxicity Study after Repeated Oral Administration in Wistar Rats with Triethoxyphenylsilane (CAS RN 780-69-8) | Author: BSL Bioservice Scientific Laboratories | Year: 2020 | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Prenatal Developmental Toxicity Study after Repeated Oral Administration in Wistar Rats with Triethoxyphenylsilane (CAS RN 780-69-8) | Author: BSL Bioservice Scientific Laboratories | Year: 2020 | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: No information; No information | Author: IUCLID; | Year: 1969; | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: No information; No information | Author: IUCLID; | Year: 1969; | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Toxicological | Acute toxicity: oral | Waiver | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation; | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: no. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation; | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of phenylsilanetriol | Author: Peter Fisk Associates | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the water solubility of phenylsilanetriol | Author: Peter Fisk Associates | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Phys-Chem | Flammability | Waiver | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Repeated inhalation Studies on Ethyl Silicate and Summary of Range Finding Data on Other Silanes | Author: Mellon Institute of Industrial Research | Year: 1951 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physical and Thermodynamic Properties: Update of Phenylchlorosilanes: PhSiCl3, Ph2SiCl2 and PhMeSiCl2. | Author: Flaningam, O. | Year: 1989 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Reaction non Classique au Cours de l'Alkylation des Halogenures d'Elements de la Colonne IVB par des Reactifs de Grignard; Cas du Tetrachlorure de Silicium. | Author: Metras, F., Lahournere, J.C., Valade, J. | Year: 1971 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Flammability | Waiver | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test in the Han Wistar Rat | Author: Harlan Laboratories Ltd. | Year: 2009 | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Organosilicon Compounds. LXVI. Electrophilic Chlorination of Phenylchlorosilanes. | Author: Lepeska, B., Chvalovsky, V. | Year: 1969 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Toxicological | Acute toxicity: inhalation | Waiver | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Rabbit Eye and Skin Injury Testing on Seven Silica Compounds. | Author: Union Carbide Corporation | Year: 1986 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Grunddatensatz für Groẞstoffe - Trichlorphenylsilan | Author: Wacker-Chemie GmbH | Year: 1991 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Grunddatensatz für Groẞstoffe - Trichlorphenylsilan | Author: Wacker-Chemie GmbH | Year: 1991 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
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| Phys-Chem | Boiling point | Robust Study Summary -- Title: Acid-Base Properties of Alkyl(Aryl)fluorosilanes in Nonaqueous Media | Author: Drozdov, V.A., Kreshkov, A.P., Romanova, A.D. | Year: 1970 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane) |
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| Toxicological | Skin irritation / corrosion | Waiver | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Trichloro(phenyl)silane Mouse Lymphoma Assay | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Trichloro(phenyl)silane Mouse Lymphoma Assay | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: yes. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Electric Moments of Organosilicon Compounds. I. Fluorides and Chlorides. | Author: Curran, C., Witucki, R.M., McCusker, P.A. | Year: 1950 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: AN EVALUATION OF THE POTENTIAL TOXICITY OF INHALED PHENYLTRIMETHYLOXYSILANE IN THE ALBINO RAT | Author: Bio-Research Laboratories | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: AN EVALUATION OF THE POTENTIAL TOXICITY OF INHALED PHENYLTRIMETHYLOXYSILANE IN THE ALBINO RAT | Author: Bio-Research Laboratories | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Oral Toxicity Study with the Reproduction / Developmental Toxicity Screening Test in Wistar Rats with Triethoxyphenylsilane (CAS 780-69-8) including a 14-Day Recovery Period | Author: Eurofins | Year: 2019 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Halogenation of Aromatic Silanes. XVII. Addition of Chlorine to Phenyltrichlorosilane. Preparation of Hexachlorocyclohexyltrichlorosilane and the Mechanism of its Formation. | Author: Motsarev, G.V. et al. | Year: 1965 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Attempts to Prepare Unsaturated Compounds from Phenylsilicon Trichloride. | Author: Kipping, F.S., Murray, A.G., Maltby, J.G. | Year: 1929 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis determination of trimehoxyphenylsilane at different pH values | Author: Weissenfeld, M | Year: 2008 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis determination of trimehoxyphenylsilane at different pH values | Author: Weissenfeld, M | Year: 2008 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: AN EVALUATION OF THE POTENTIAL TOXICITY OF INHALED PHENYLTRIMETHYLOXYSILANE IN THE ALBINO RAT - ADDENDUM | Author: Bio-Research Laboratories | Year: 1981 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: AN EVALUATION OF THE POTENTIAL TOXICITY OF INHALED PHENYLTRIMETHYLOXYSILANE IN THE ALBINO RAT - ADDENDUM | Author: Bio-Research Laboratories | Year: 1981 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of hydrolysis half life at pH 7 for trialkoxysilanes Verson 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of Trimethoxy(phenyl)silane; Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of trimethoxy(phenyl)silane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2011; 2018; 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of hydrolysis half life at pH 7 for trialkoxysilanes Verson 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of Trimethoxy(phenyl)silane; Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of trimethoxy(phenyl)silane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2011; 2018; 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Reaction of Diphenyldichlorosilane Disproportionation | Author: Andrianov, K.A., Kotov, V.M. | Year: 1967 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Toxicological | Repeated dose toxicity: inhalation | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Studies in Organo-Silicon Synthesis. III. Two-Stage Wurtz Reactions with Silicon Halides. | Author: Schumb, W.C., Saffer, C.M. Jr. | Year: 1941 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of dimethoxy(methyl)phenylsilane; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of dimethoxy(methyl)phenylsilane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of dimethoxy(methyl)phenylsilane; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of dimethoxy(methyl)phenylsilane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Analyse von Organosilicium-Verbindungen VI. Retentions Indicies der Organosilicium Verbindungen bei der Gas Chromatographie. | Author: Wurst, M., Churacek, J. | Year: 1971 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Attempts to Prepare Unsaturated Compounds from Phenylsilicon Trichloride. | Author: Kipping, F.S., Murray, A.G., Maltby, J.G. | Year: 1929 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Toxicological | Repeated dose toxicity: oral | Waiver | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of triethoxy(phenyl)silane; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of triethoxy(phenyl)silane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of triethoxy(phenyl)silane; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of triethoxy(phenyl)silane | Author: Peter Fisk Associates; Vitis Regulatory | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physical and Thermodynamic Properties: Update of Phenylchlorosilanes: PhSiCl3, Ph2SiCl2 and PhMeSiCl2. | Author: Flaningam, O. | Year: 1989 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Grunddatensatz für Groẞstoffe - Trichlorphenylsilan | Author: Wacker-Chemie GmbH | Year: 1991 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Grunddatensatz für Groẞstoffe - Trichlorphenylsilan | Author: Wacker-Chemie GmbH | Year: 1991 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: not specified. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of phenylsilanetriol | Author: Peter Fisk Associates | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3; QSAR Prediction Reporting Format (QPRF) for the vapour pressure of phenylsilanetriol | Author: Peter Fisk Associates | Year: 2014; 2022 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Silicon-Containing Heterocyclic Compounds. Thermal Reactions of Dichlorosilylene with Unsaturated Compounds. | Author: Chernyshev, E.A. et al. | Year: 1978 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Silicon-Containing Heterocyclic Compounds. VIII. Participation of Dichlorosilylene in Thermal Reactions Leading to the Formation of Silicon-Containing Heterocycles. | Author: Chernyshev E.A. et al. | Year: 1971 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Synthesis of 1,1-Dichloro-3,3,3-Trimethyl-1-Phenyldisiloxane. | Author: Andrianov, K.A., Burlova, E.A., Tikhonov, V.S. | Year: 1969 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: The Direct Synthesis of Phenylchlorosilanes | Author: Rochow, E.G., Gilliam, W.F. | Year: 1945 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: no. | - |