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| Study name | Short Description | Data Owner |
|---|---|---|
| Chemical Safety Report | Chemical Safety Report | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Stoffwerte γ-Butyrolacton | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Stoffwerte γ-Butyrolacton | Author: BASF AG | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruckmessung | Author: BASF AG | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Bestimmung des Verteilungskoeffizienten POW von γ-Butyrolacton in n-Octanol/Wasser | Author: BASF AG | Year: 1987 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Bestimmung des Verteilungskoeffizienten POW von γ-Butyrolacton in n-Octanol/Wasser | Author: BASF AG | Year: 1987 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Bestimmung der Wasserlöslichkeit | Author: BASF AG | Year: 1987 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Bestimmung der Wasserlöslichkeit | Author: BASF AG | Year: 1987 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Karteibogen | Author: BASF AG | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Karteibogen | Author: BASF AG | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Stability: Dissociation constant | Robust Study Summary -- Author: ISP | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Stability: Dissociation constant | Right to refer to study -- Author: ISP | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: The Chemical Interconversion of GHB and GBL: Forensic Issues and Implications | Author: Ciolino L.A. et al. | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and Bioaccumulation of Existing Chemical Substances under the Chemical Substances Control Law. | Author: METI | Year: 2007 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Test protocol of BOD study | Author: BASF AG | Year: 1977 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Test protocol of BOD study | Author: BASF AG | Year: 1977 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Test protocol Zahn-Wellens-study 'Standversuch' | Author: BASF AG | Year: 1977 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Test protocol Zahn-Wellens-study 'Standversuch' | Author: BASF AG | Year: 1977 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Estimation of Log KOC using EPA KOCWIN v2.00 for γ-Butyrolactone CAS# 96-48-0 | Author: ISP | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Adsorption/desorption | Right to refer to study -- Title: Estimation of Log KOC using EPA KOCWIN v2.00 for γ-Butyrolactone CAS# 96-48-0 | Author: ISP | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Report on the study of acute toxicity of butyrolactone on Leuciscus idus | Author: BASF AG | Year: 1990 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Report on the study of acute toxicity of butyrolactone on Leuciscus idus | Author: BASF AG | Year: 1990 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Test report on fish (golden orfe) toxicity study | Author: BASF AG | Year: 1977 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Test report on fish (golden orfe) toxicity study | Author: BASF AG | Year: 1977 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Test report on fish (golden orfe) toxicity study | Author: BASF AG | Year: 1977 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Test report on fish (golden orfe) toxicity study | Author: BASF AG | Year: 1977 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Report on the acute effect of butyrolactone to the waterflea Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Report on the acute effect of butyrolactone to the waterflea Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Test protocol Algae study with γ-butyrolactone. | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Test protocol Algae study with γ-butyrolactone. | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Statistical evaluation with ToxRatPro (v2.09) of BASF algae study report No. 2/00w9/88 (test date: 03 June 1988) | Author: ECT Oekotoxikologie GmbH | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Statistical evaluation with ToxRatPro (v2.09) of BASF algae study report No. 2/00w9/88 (test date: 03 June 1988) | Author: ECT Oekotoxikologie GmbH | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Structure-Toxicity Relationships for Selected Lactones to Tetrahymena pyriformis | Author: Schultz TW and Deweese AD | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Industrial hygiene orientating investigation. | Author: BASF AG | Year: 1960 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Industrial hygiene orientating investigation. | Author: BASF AG | Year: 1960 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1960 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1960 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1960 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Industrial hygiene orientating investigation | Author: BASF AG | Year: 1960 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Report: Gamma-Butyrolactone - Acute eye irritation in rabbits | Author: BASF AG | Year: 2005 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Report: Gamma-Butyrolactone - Acute eye irritation in rabbits | Author: BASF AG | Year: 2005 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Gamma-Butyrolactone Murine Local Lymph Node Assay (LLNA) | Author: BASF SE | Year: 2010 | Guideline: B.42, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Gamma-Butyrolactone Murine Local Lymph Node Assay (LLNA) | Author: BASF SE | Year: 2010 | Guideline: B.42, 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Gamma-Butyrolactone (Cas No. 96-48-0) In F344/N Rats and B6C3Fl Mice (Gavage Studies) | Author: NTP | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: NTP Technical Report on the Toxicology and Carcinogenesis Studies of Gamma-Butyrolactone (Cas No. 96-48-0) In F344/N Rats and B6C3Fl Mice (Gavage Studies) | Author: NTP | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity test data of existing chemical substances based on the toxicity investigation of the industrial safety and health law Supplement 2 | Author: Japan MHLW | Year: 2000 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity test results for 250 chemicals | Author: Haworth S. et al. | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome Aberration and Sister Chromatid Exchange Tests in Chinese Hamster Ovary Cells In Vitro: II. Results with 20 Chemicals | Author: Loveday K.S. et al. | Year: 1989 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Toxicology and Carcinogenesis Studies of γ-Butyrolactone (CAS No. 96-48-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies) | Author: NTP | Year: 1992 | Guideline: 477 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Chemical Mutagenesis Testing in Drosophila. X. Results of 70 Coded Chemicals Tested for the National Toxicology Program | Author: Foureman P et. al. | Year: 1994 | Guideline: 477 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Performance of 181 chemicals in a Drosophila assay predominantly monitoring interchromosomal mitotic recombination | Author: Vogel E.W. and Nivard M.J.M. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: Toxicology and Carcinogenesis Studies of γ-Butyrolactone (CAS No. 96-48-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies) | Author: NTP | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: Toxicology and Carcinogenesis Studies of γ-Butyrolactone (CAS No. 96-48-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies) | Author: NTP | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeat Dose and Reproductive / Developmental Toxicity Screening Test of 1,4-Butanediol in Rats | Author: MHW | Year: 1999 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: OECD SIDS (1,4-Butanediol; CASRN 110-63-4) | Author: OECD | Year: 2000 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratogenicity Test of γ-Butyrolactone in the Sprague-Dawley Rat | Author: Kronevi T. et. al. | Year: 1988 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined Repeat Dose and Reproductive / Developmental Toxicity Screening Test of 1,4-Butanediol in Rats | Author: MHW | Year: 1999 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: OECD SIDS (1,4-Butanediol; CASRN 110-63-4) | Author: OECD | Year: 2000 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Developmental toxicity evaluation of 1,4-Butanediol administered by gavage to Swiss mice on gestation days 6 through 15. | Author: NTP | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |