Product Zoom Image

CAS 80-05-7 | Data Package > 1000 t/a (Affiliates of BPA Consortium and ACC members)

Price: POA
All endpoints used in the EU REACH dossier and needed in the Turkey REACH dossier.

Product Features:

  • CAS 80-05-7

  • EC 201-245-8

  • 4,4'-(1-Methylethylidene)bisphenol

  • Bisphenol A

  • BPA

Includes:

Study name Short Description Data Owner
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: Ashford's Dictionary of Industrial Chemicals | Author: Ashford RD | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Grunddatensatz für Altstoffe über 1000 jato | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Right to refer to study -- Title: Grunddatensatz für Altstoffe über 1000 jato | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Handbook of Chemistry and Physics | Author: CRC | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Bisphenol-A: International Chemical Safety Cards | Author: IPCS | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Handbook of Environmental Fate and Exposure Data for Organic Chemicals. Volume 1. Large Production and Priority Pollutants | Author: Howard PH et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: The Merck Index. An encyclopedia of chemicals drugs and biologicals | Author: Merck Index | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Hazardous Materials Handbook | Author: Pohanish R.P., Greene S.A. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Dictionary of Organic Chemicals | Author: Eyre Spottiswood | Year: 1965 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Sax's Dangerous Properties of Industrial Materials 9th Edition 10th Edition | Author: Sax N.I. Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Ullmann's Encyclopedia of Industrial Chemistry | Author: Gerhartz W. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: The Heat of Combustion of 2,2'-bis-(4-hydroxyphenyl)-propane | Author: Hubbard W.H,. Knowlton J.W. and Huffman H.M. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Physical and Thermodynamic Properties of Pure Chemicals Data Compilation | Author: DIPPR | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Handbook of Chemistry and Physics | Author: CRC | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Dictionary of Organic Chemicals | Author: Eyre Spottiswood | Year: 1965 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Bisphenol-A: International Chemical Safety Cards | Author: IPCS | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Sax's Dangerous Properties of Industrial Materials 9th Edition 10th Edition | Author: Sax N.I., Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: No information | Author: von Braun | Year: 1925 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: Hawley's Condensed Chemical Dictionary 11th ed. | Author: Hawley | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Boiling point Robust Study Summary -- Title: The Merck Index. An encyclopedia of chemicals drugs and biologicals | Author: Merck Index | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Density Robust Study Summary -- Title: Hawley's Condensed Chemical Dictionary 11th ed. | Author: Hawley | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Density Robust Study Summary -- Title: Sax's Dangerous Properties of Industrial Materials 9th Edition 10th Edition | Author: Sax N.I., Lewis R.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Density Robust Study Summary -- Title: Ullmann's Encyclopedia of Industrial Chemistry | Author: Gerhartz W. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Density Robust Study Summary -- Title: The Heat of Combustion of 2,2'-bis-(4-hydroxyphenyl)-propane | Author: Hubbard W.H,. Knowlton J.W. and Huffman H.M. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Vapor pressure measurements (Dampfdruck) | Author: Bayer AG | Year: 1988 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Right to refer to study -- Title: Vapor pressure measurements (Dampfdruck) | Author: Bayer AG | Year: 1988 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Bisphenol A | Author: American Industrial Hygiene Association | Year: 1967 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Chemical Safety Sheets: Working Safely with Hazardous Chemicals | Author: Kluwer | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Robust Study Summary -- Title: EPISuite v3.12 | Author: EPA | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Grunddatensatz für Altstoffe über 1000 jato | Author: Bayer AG | Year: 1989 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Water solubility Right to refer to study -- Title: Grunddatensatz für Altstoffe über 1000 jato | Author: Bayer AG | Year: 1989 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Aqueous solubilities of estrone 17-β-estradiol 17-α-ethynylestradiol and bisphenol A | Author: Shareef A. et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Degradation of bisphenol A in natural waters | Author: Dorn P.B., Chou C-S, and Gentempo J.J. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Handbook of Environmental Fate and Exposure Data for Organic Chemicals. Volume 1. Large Production and Priority Pollutants | Author: Howard PH et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Bisphenol A | Author: American Industrial Hygiene Association | Year: 1967 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Ullmann's Encyclopedia of Industrial Chemistry | Author: Gerhartz W. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Water solubility | Author: Alexander et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Verteilungskoeffizient Bisphenol A | Author: Bayer AG | Year: 1989 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Partition coefficient Right to refer to study -- Title: Verteilungskoeffizient Bisphenol A | Author: Bayer AG | Year: 1989 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Substituent constants for correlation analysis in chemistry and biology | Author: Hansch C. Leo A. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Handbook of Environmental Fate and Exposure Data for Organic Chemicals. Volume 1. Large Production and Priority Pollutants | Author: Howard P.H. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: No information | Author: Korenman Gorokhov | Year: 1973 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Diphenylol propane: Determination of the n-octanol/water partition coefficient using a reverse-phase HPLC method | Author: Eadsforth C.V. | Year: 1983 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Partition coefficient Right to refer to study -- Title: Diphenylol propane: Determination of the n-octanol/water partition coefficient using a reverse-phase HPLC method | Author: Eadsforth C.V. | Year: 1983 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Stability: thermal, sunlight, metals Robust Study Summary -- Title: Determination of Safety-Relevant Data of Bisphenol A | Author: Heinz U. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Stability: thermal, sunlight, metals Right to refer to study -- Title: Determination of Safety-Relevant Data of Bisphenol A | Author: Heinz U. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Stability: Dissociation constant Robust Study Summary -- Title: Acidity constants of some phenol derivatives in water ethanol and methylene chloride | Author: Zjawiony I., Pasciak J. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Stability: Dissociation constant Robust Study Summary -- Title: ACD Labs software programme, release 7.00, version 7.05, 2003-04-13 | Author: ACD Labs | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Stability: Dissociation constant Right to refer to study -- Title: ACD Labs software programme, release 7.00, version 7.05, 2003-04-13 | Author: ACD Labs | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Stability: Dissociation constant Robust Study Summary -- Title: The aqueous phase in the interfacial synthesis of polycarbonates. 1. Ionic equilibria and experimental solubilities in the BPA-NaOH-H2O system | Author: Kosky P.E., Guggenheim E.A. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Flammability Robust Study Summary -- Title: Determination of Safety-Relevant Data of Bisphenol A | Author: Heinz U. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Flammability Right to refer to study -- Title: Determination of Safety-Relevant Data of Bisphenol A | Author: Heinz U. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Flash point Robust Study Summary -- Title: Ullmann's Encyclopedia of Industrial Chemistry | Author: Gerhartz W. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Ullmann's Encyclopedia of Industrial Chemistry | Author: Gerhartz W. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Safety considerations in conveying of bulk solids and powders | Author: Grossel S.S. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Chemical Safety Sheets: Working Safely with Hazardous Chemicals | Author: Kluwer | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Bisphenol-A (A safety and handling guide) | Author: The Society of the Plastics Industry | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Phys-Chem | Auto-ignition temperature Right to refer to study -- Title: Bisphenol-A (A safety and handling guide) | Author: The Society of the Plastics Industry | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Acute skin irritation test (patch test) of bisphenol A in rabbits | Author: Leuschner P.J. | Year: 2000 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Acute skin irritation test (patch test) of bisphenol A in rabbits | Author: Leuschner P.J. | Year: 2000 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Robust Study Summary -- Title: Acute eye irritation study of bisphenol A by instillation into the conjunctival sac of rabbits | Author: Leuschner P.J. | Year: 2000 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Right to refer to study -- Title: Acute eye irritation study of bisphenol A by instillation into the conjunctival sac of rabbits | Author: Leuschner P.J. | Year: 2000 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Local lymph node assay in mice (LLNA/IMDS) | Author: Vohr H-W | Year: 2002 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Right to refer to study -- Title: Local lymph node assay in mice (LLNA/IMDS) | Author: Vohr H-W | Year: 2002 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Bisphenol A: Study of photoreactive potential in mice (LLNA/IMDS) | Author: Vohr H-W | Year: 2003 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | Skin sensitisation Right to refer to study -- Title: Bisphenol A: Study of photoreactive potential in mice (LLNA/IMDS) | Author: Vohr H-W | Year: 2003 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: 4,4'-Isopropylidenediphenol (bisphenol-A) | Author: EC | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Chromosomal aberrations and sister chromatid exhange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals. | Author: Ivett J.L. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity test data of existing chemical substances | Author: Japan Chemical Industry Ecology-Toxicology & Information Center Japan | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: results for 31 coded compounds in the National Toxicology Program | Author: Myhr B.C.. Caspary W.J. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Mammalian Erythrocyte Micronucleus Test | Author: Gudi R., Krsmanovic L. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Genetic toxicity in vivo Right to refer to study -- Title: Mammalian Erythrocyte Micronucleus Test | Author: Gudi R., Krsmanovic L. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Exposure of mouse oocytes to bisphenol A causes meiotic arrest but not aneuploidy | Author: Eichenlaub-Ritter U. et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Bisphenol A effects on the growing mouse oocyte are influenced by diet | Author: Muhlhauser A. et al. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Genetic toxicity in vivo Robust Study Summary -- Title: Evaluation of aneugenic effects of bisphenol A in somatic and germ cells of the mouse | Author: Pacchierotti F. et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Bisphenol A: Acute oral toxicity study in the rat | Author: Jones J.R. | Year: 1985 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: oral Right to refer to study -- Title: Bisphenol A: Acute oral toxicity study in the rat | Author: Jones J.R. | Year: 1985 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: Carcinogenesis bioassay of bisphenol A (CAS No. 80-05-7) in F344 rats and B6C3F1 mice (feed study) | Author: United States National Toxicology Program | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Bisphenol A: Acute aerosol toxicity study with Fischer 344 rats | Author: Nitschke K.D. et al. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: inhalation Right to refer to study -- Title: Bisphenol A: Acute aerosol toxicity study with Fischer 344 rats | Author: Nitschke K.D. et al. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: The acute and subacute toxicity of diphenylol propane | Author: Carpenter C.P., Weil C.S. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: The acute and subacute toxicity of diphenylol propane | Author: Carpenter C.P., Weil C.S. | Year: 1948 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: Range finding tests on bisphenol A | Author: West J.S., Carpenter C.P. | Year: 1965 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: Range finding tests on bisphenol A | Author: West J.S., Carpenter C.P. | Year: 1965 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: 4,4'-Isopropylidenediphenol (bisphenol-A) | Author: EC | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: 4,4'-Isopropylidenediphenol (bisphenol-A) | Author: EC | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Extrapolation of plasma clearance to understand species differences in toxicokinetics of bisphenol A | Author: Torka Poet & Sean Hays | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Update to Species extrapolation of Clearance of BPA | Author: Sean Hays | Year: 2020 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in humans following a single oral administration. | Author: Thayer K. A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Are typical human serum BPA concentrations measureable and sufficient to be estrogenic in the general population? | Author: Teeguarden J. et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in neonatal and adult rhesus monkeys. | Author: Doerge D.R. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in neonatal and adult Sprague-Dawley rats. | Author: Doerge D.R. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Lactational transfer of bisphenol A in Sprague-Dawley rats. | Author: Doerge D.R. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Distribution of bisphenol A into tissues of adult neonatal and fetal Sprague-Dawley rats. | Author: Doerge D.R. et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in neonatal and adult CD-1 mice: Inter-species comparisons with Sprague-Dawley rats and rhesus monkeys. | Author: Doerge D.R. et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in serum and adipose tissue following intravenous administration to adult female CD-1 mice. | Author: Doerge D.R. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Concurrent determination of bisphenol A pharmacokinetics in maternal and fetal rhesus monkeys. | Author: Patterson T.A. et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetic modeling: Prediction and evaluation of route dependent dosimetry of bisphenol A in monkeys with extrapolation to humans. | Author: Fisher J. et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Prediction and evaluation of route dependent dosimetry of BPA in rats at different life stages using a physiologically based pharmacokinetic model. | Author: Yang X., Doerge D. R. and Fisher J. W. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Unravelling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling. | Author: Yang X. and Fisher J. W. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Development of a physiologically based pharmacokinetic model for assessment of human exposure to bisphenol A. | Author: Yang X. et al. | Year: 2015 | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Quantification of deuterated bisphenol A in serum tissues and excreta from adult Sprague-Dawley rats using liquid chromatography with tandem mass spectrometry. | Author: Twaddle N. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: The contribution of dermal exposure to the internal exposure of bisphenol A in man | Author: H. Mielke F., Partosch U. and Gundert-Remy | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Twenty-four hour human urine and serum profiles of bisphenol A during high-dietary exposure. | Author: Teeguarden J.G. et al. | Year: 2011 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: 24-hour human urine and serum profiles of bisphenol A: Evidence against sublingual absorption following ingestion in soup | Author: Justin G. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: 24-Hour human urine and serum profiles of bisphenol A following ingestion in soup: individual pharmacokinetic data and demographics. | Author: Teeguarden J.G. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women | Author: Justin G. et al. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Pharmacokinetics of bisphenol A in humans following dermal administration | Author: Alan F. et al. | Year: 2020 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Dermal absorption Robust Study Summary -- Title: The In Vitro Percutaneous Absorption and Metabolism of Radiolabelled Bisphenol A (BPA) Through Fresh Human Skin | Author: Toner F. | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Dermal absorption Right to refer to study -- Title: The In Vitro Percutaneous Absorption and Metabolism of Radiolabelled Bisphenol A (BPA) Through Fresh Human Skin | Author: Toner F. | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Dermal penetration of bisphenol A in human skin contributes marginally to total exposure | Author: Anne-Laure Demierre et al. | Year: 2012 | Guideline: 428 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Bisphenol A bisphenol S and 4-hydroxyphenyl 4-isoprooxyphenylsulfone (BPSIP) in urine and blood of cashiers. | Author: Thayer K. A. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Human in vitro percutaneous absorption of bisphenol S and bisphenol A: A comparative study | Author: C. Champmartin et al. | Year: 2020 | Guideline: 428 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Right to refer to study -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Right to refer to study -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Right to refer to study -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. et al. | Year: 2002 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Right to refer to study -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. et al. | Year: 2002 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Subacute oral toxicity study of ethynylestradiol and bisphenol A based on the draft protocol for the 'Enhanced OECD Test Guideline no. 407' | Author: Yamasaki K. et al. | Year: 2002 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Carcinogenesis bioassay of bisphenol A (CAS No. 80-05-7) in F344 rats and B6C3F1 mice (feed study) | Author: United States National Toxicology Program | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs: PART II - Toxicological assessment and risk characterisation | Author: EFSA | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: Assessment of recent developmental immunotoxicity studies with bisphenol A in the context of the 2015 EFSA t-TDI | Author: Ellen V.S. et al. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: A statement on the developmental immunotoxicity of bisphenol A (BPA): answer to the question from the Dutch Ministry of Health Welfare and Sport | Author: EFSA CEF Panel (EFSA Panel on Food Contact Materials Enzymes Flavourings and Processing Aids) | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: oral Robust Study Summary -- Title: A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results | Author: L. Camacho et al. | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Bisphenol A: 13-week aerosol toxicity study with Fischer 344 rats | Author: Nitschke K.D. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: inhalation Right to refer to study -- Title: Bisphenol A: 13-week aerosol toxicity study with Fischer 344 rats | Author: Nitschke K.D. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Recommendation from the Scientific Committee on Occupational Exposure Limits for Bisphenol-A | Author: Scientific Committee on Occupational Exposure Limits | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Inhalation Toxicity of Bisphenol A and Its Effect on Estrous Cycle Spatial Learning and Memory in Rats upon Whole-Body Exposure | Author: Yong Hyun Chung et al. | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Right to refer to study -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Rat two-generation reproductive toxicity study of bisphenol A | Author: Ema M. et al. | Year: 2001 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Teratologic evaluation of bisphenol A (CAS No. 80-05-7) administered to CD rats on gestational days 6 through 15 | Author: George J.D. et al. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Developmental treatment with bisphenol A or ethinyl estradiol causes few alterations on early preweaning measures. | Author: Ferguson S. A., Law C.D., and Abshire J. S. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Erratum: Developmental treatment with bisphenol A or ethinyl estradiol causes few alterations on early preweaning measures. | Author: Ferguson S. A., Law C.D., and Abshire J. S. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Low oral doses of bisphenol A increase volume of the sexually dimorphic nucleus of the preoptic area in male but not female rats at postnatal day 21. | Author: He Z., Paule M.G., and Ferguson S. A. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Developmental treatment with bisphenol A causes few alterations on measures of postweaning activity and learning. | Author: Ferguson S. A., Law C.D., and Abshire J. S. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Developmental treatment with ethinyl estradiol but not bisphenol A causes alterations in sexually dimorphic behaviors in male and female Sprague-Dawley rats. | Author: Ferguson S.A., Law C.D., and Kissling G. E. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Pre- and postnatal bisphenol A treatment does not alter the number of tyrosine hydroxylase-positive cells in the anteroventral periventricular nucleus (AVPV) of weanling male and female rats. | Author: Ferguson S.A. Paule M. G. and He Z. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Lack of effects for dietary exposure of bisphenol A during in utero and lactational periods on reproductive development in rat offspring. | Author: Kobayashi K. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Dietary exposure to low doses of bisphenol A: effects on reproduction and dev elopment in two generations of C57BL/6J mice. | Author: Kobayashi K. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Impact of low dose oral exposure to bisphenol A (BPA) on juvenile and adult rat exploratory and anxiety behavior: A CLARITY-BPA consortium study. | Author: Rebuli M. E. et al. | Year: 2015 | Klimisch score: exploratory study as part of the CLARITY study. | Adequacy: supporting study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Effects of developmental exposure to bisphenol A on spatial navigational learning and memory in rats: A CLARITY-BPA study. | Author: Johnson S. A. et al. | Year: 2015 | Klimisch score: Exploratory study as part of the CLARITY study | Adequacy: supporting study. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study | Author: Sheryl E. et al. | Year: 2016 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study | Author: Sheryl E. Arambula, Dereje Jima, and Heather B. Patisaul | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results | Author: L. Camacho et al. | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Toxicological | Developmental toxicity/teratogenicity Robust Study Summary -- Title: Gene expression and DNA methylation changes in the hypothalamus and hippocampus of adult rats developmentally exposed to bisphenol A or ethinyl estradiol: a CLARITY-BPA consortium study | Author: Ana Cheong et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Right to refer to study -- Title: Two-generation reproductive toxicity evaluation of Bisphenol A (BPA; CAS No. 80-05-7) administered in the feed to CD-1® Swiss mice (modified OECD 416) | Author: Tyl R.W. | Year: 2007 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Right to refer to study -- Title: Two-generation reproductive toxicity study of dietary bisphenol A (BPA) in CD-1® (Swiss) mice | Author: Tyl R. et al. | Year: 2008 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Right to refer to study -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Three-generation reproductive toxicity study of dietary bisphenol A in CD Sprague-Dawley rats | Author: Tyl R.W. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Rat two-generation reproductive toxicity study of bisphenol A | Author: Ema M. et al. | Year: 2001 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Toxicity evaluation of bisphenol A administered by gavage to Sprague-Dawley rats from gestation day 6 through postnatal day 90. | Author: Delclos K. B. et al. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: CORRIGENDUM: Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90 | Author: K. Barry Delclos et al. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Memorandum: Review of a specialized oral developmental toxicity study on bisphenol A (BPA) entitled 'Evaluation of the toxicity of bisphenol A (BPA) in male and female Sprague-Dawley rats exposed orally from gestation day 6 through postnatal day 90' | Author: GuJ. Mitkus R. J. | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Memorandum: Request for CFSAN Pathology comments on mammary gland hyperplasia in the NCTR subchronic (PND 21 and 90) oral rat study with BPA | Author: Mog. S. Francke-Carroll S. | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: NCTR Evaluation of the toxicity of Bisphenol A (BPA) in Male and Female Sprague-Dawley Rats Exposed Orally from Gestation Day 6 through Postnatal Day 90 | Author: Barry Delclos | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results | Author: L. Camacho et al. | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland and uterus of NCTR Sprague-Dawley rats | Author: Luísa Camacho et al. | Year: 2015 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Comparison of lifestage-dependent internal dosimetry for bisphenol A ethinyl estradiol a reference estrogen and endogenous estradiol to test an estrogenic mode of action in Sprague-Dawley rats. | Author: Churchwell M. I. et al. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Response to Hunt et al. Invalid controls undermine conclusions of FDA studies. | Author: Delclos K. B. and Doerge D. R. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: In utero and lactational exposure to bisphenol A in contrast to ethinyl estradiol does not alter sexually dimorphic behavior, puberty, fertility and anatomy of female LE rats. | Author: Ryan B. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Toxicity to reproduction Robust Study Summary -- Title: Gestational and lactational exposure to ethinyl estradiol but not bisphenol A decreases androgen-dependent reproductive organ weights and epididymal sperm abundance in the male Long Evans hooded rat. | Author: Howdeshell K. L. et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: Carcinogenesis bioassay of bisphenol A (CAS No. 80-05-7) in F344 rats and B6C3F1 mice (feed study) | Author: United States National Toxicology Program | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: Toxicity evaluation of bisphenol A administered by gavage to Sprague-Dawley rats from gestation day 6 through postnatal day 90. | Author: Delclos K. B. et al. | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: Memorandum: Review of a specialized oral developmental toxicity study on bisphenol A (BPA) entitled 'Evaluation of the toxicity of bisphenol A (BPA) in male and female Sprague-Dawley rats exposed orally from gestation day 6 through postnatal day 90' | Author: GuJ. Mitkus R. J. | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: Memorandum: Request for CFSAN Pathology comments on mammary gland hyperplasia in the NCTR subchronic (PND 21 and 90) oral rat study with BPA | Author: Mog. S. Francke-Carroll S. | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: NCTR Evaluation of the toxicity of Bisphenol A (BPA) in Male and Female Sprague-Dawley Rats Exposed Orally from Gestation Day 6 through Postnatal Day 90 | Author: Barry Delclos | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: NTP Research Report on the CLARITY-BPA Core Study: A Perinatal and Chronic Extended-Dose-Range Study of Bisphenol A in Rats. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Carcinogenicity Robust Study Summary -- Title: A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results | Author: L. Camacho et al. | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Neurotoxicity Robust Study Summary -- Title: A dietary developmental neurotoxicity study of bisphenol A in rats | Author: Stump D.G. | Year: 2009 | Guideline: 426 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Neurotoxicity Right to refer to study -- Title: A dietary developmental neurotoxicity study of bisphenol A in rats | Author: Stump D.G. | Year: 2009 | Guideline: 426 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Neurotoxicity Robust Study Summary -- Title: Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-BPA consortium study | Author: Arambula S.E. et al. | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Neurotoxicity Robust Study Summary -- Title: Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: A CLARITY-BPA consortium follow-up study | Author: Shannah K Witchey, Joelle Fuchs, and Heather B. Patisaul | Year: 2019 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Endocrine disruptor mammalian screening - In vivo (level 3) Robust Study Summary -- Title: Gene expression changes in the immature rat uterus: Effects of uterotrophic and sub-uterotrophic doses of bisphenol A | Author: Ashby J., Odum J. | Year: 2004 | Guideline: 440 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Endocrine disruptor mammalian screening - In vivo (level 3) Robust Study Summary -- Title: The OECD program to validate the rat uterotrophic bioassay. phase 2: coded single-dose studies | Author: Kanno J. et al. | Year: 2003 | Guideline: 440 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Immunotoxicity Robust Study Summary -- Title: Clarity-BPA: Effects of chronic Bisphenol A exposure on the immune system: Part 1 - Quantification of the relative number and proportion of leukocyte populations in the spleen and thymus | Author: Li J. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Immunotoxicity Robust Study Summary -- Title: CLARITY-BPA: Effects of Chronic Bisphenol A Exposure on the Immune System: Part 2 - Characterization of Lymphoproliferative and Immune Effector Responses by Splenic Leukocytes. | Author: Li J. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: Gene expression changes in the immature rat uterus: Effects of uterotrophic and sub-uterotrophic doses of bisphenol A | Author: Ashby J., Odum J. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: The OECD program to validate the rat uterotrophic bioassay. phase 2: coded single-dose studies | Author: Kanno J. et al. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: The OECD program to validate the rat uterotrophic bioassay. phase 2: dose-response studies | Author: Kanno J. et al. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: Effects of bisphenol A on incidence and severity of cardiac lesions in the NCTR-Sprague-Dawley rat: A CLARITY-BPA study | Author: Gear R., Kendziorski J.A., and Belcher S.M. | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: Effects of continuous bisphenol A exposure from early gestation on 90 day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study. | Author: Dere E. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: Bisphenol A Exposure Ovarian Follicle Numbers and Female Sex Steroid Hormone Levels: Results From a CLARITY-BPA Study | Author: Shreya Patel et al. | Year: 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: CLARITY-BPA: Bisphenol A or Propylthiouracil on Thyroid Function and Effects in the Developing Male and Female Rat Brain | Author: R. Bansal and R. T. Zoeller | Year: 2019 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: Low-Dose Bisphenol A in a Rat Model of Endometrial Cancer: A CLARITY-BPA Study | Author: Yuet-Kin Leung et al. | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Specific investigations: other studies Robust Study Summary -- Title: A Combined Morphometric and Statistical Approach to Assess Nonmonotonicity in the Developing Mammary Gland of Rats in the CLARITY-BPA Study | Author: Maël Montévil et al. | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Bisphenol A: Flow-through acute toxicity to the fathead minnow | Author: Alexander H.C., Bartlett E.A., and Boggs G.U. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Bisphenol A: Flow-through acute toxicity to the fathead minnow | Author: Alexander H.C., Bartlett E.A., and Boggs G.U. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Bisphenol A: Acute aquatic toxicity | Author: Alexander H.C. et al. | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: 96-hr Flow-Through Acute Toxicity Test with the Atlantic Silverside | Author: Springborn Bionomics | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: 96-hr Flow-Through Acute Toxicity Test with the Atlantic Silverside | Author: Springborn Bionomics | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Bisphenol A - Acute toxicity to Sheepshead Minnow (Cyprinodon variegatus) Under Flow-Through Conditions Following OPPTS Draft Guideline 850.1075 and OECD Guideline 203 | Author: Sayers L. | Year: 2009 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Bisphenol A - Acute toxicity to Sheepshead Minnow (Cyprinodon variegatus) Under Flow-Through Conditions Following OPPTS Draft Guideline 850.1075 and OECD Guideline 203 | Author: Sayers L. | Year: 2009 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Fish Prolonged Toxicity Test with Brachydanio rerio 14-day Bisphenol A | Author: Bayer AG | Year: 1998 | Guideline: 204 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Fish Prolonged Toxicity Test with Brachydanio rerio 14-day Bisphenol A | Author: Bayer AG | Year: 1998 | Guideline: 204 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: The acute toxicity of Parabis A and Bisphenol A to the sheepshead minnow cyprinodon variegates | Author: Emmitte J.A. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: The acute toxicity of Parabis A and Bisphenol A to the sheepshead minnow cyprinodon variegates | Author: Emmitte J.A. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: The acute toxicity of diphenylolpropane to rainbow trout (Salmo gairdneri) | Author: Reif B., Phil M. | Year: 1979 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: The acute toxicity of diphenylolpropane to rainbow trout (Salmo gairdneri) | Author: Reif B., Phil M. | Year: 1979 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Letale Wirkung beim Zebrabärbling - Brachydanio rerio - LC0 / LC50 / LC100 48-96 Stunden | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Letale Wirkung beim Zebrabärbling - Brachydanio rerio - LC0 / LC50 / LC100 48-96 Stunden | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Morphometric signatures of exposure to endocrine disrupting chemicals in zebrafish eleutheroembryos. | Author: Martínez Rubén et al. | Year: 2019 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A: Daphnid Static Acute Toxicity Test | Author: Alexander H.C., Milazzo D.P., and Boggs G.U. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A: Daphnid Static Acute Toxicity Test | Author: Alexander H.C., Milazzo D.P., and Boggs G.U. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A: Acute aquatic toxicity | Author: Alexander H.C. et al. | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute Toxicity of Bisphenol A To The Mysid (Mysidopsis bahia) Under Flow-Through Conditions | Author: Springborn Bionomics | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Acute Toxicity of Bisphenol A To The Mysid (Mysidopsis bahia) Under Flow-Through Conditions | Author: Springborn Bionomics | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A (BPA) - Acute Toxicity to Midges (Chironomus tentans) Under Flow-through conditions | Author: Springborn Smithers | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A (BPA) - Acute Toxicity to Midges (Chironomus tentans) Under Flow-through conditions | Author: Springborn Smithers | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute and chronic toxicity testing of bisphenol A with aquatic invertebrates and plants. | Author: Mihaich E.M. et al. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Ecotoxicological evaluation of the risk posed by bisphenol A triclosan and 4-nonylphenol in coastal waters using early life stages of marine organisms (Isochrysis galbana Mytilus galloprovincialis Paracentrotus lividus and Acartia clausi) | Author: Tato T. et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A migration from plastic materials: direct insight of ecotoxicity in Daphnia magna | Author: Catarina Mansilha et al. | Year: 2013 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Covert signal disruption: anti-ecdysteroidal activity of Bisphenol A involves cross-talk between signaling pathways | Author: Mu X et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Multi-generational effects of four selected environmental oestrogens on Daphnia magna | Author: Brennan S.J. et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Diphenylol Propane: Acute Toxicity to Daphnia magna and Selenastrum capricornutum | Author: Stephenson R.R. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Diphenylol Propane: Acute Toxicity to Daphnia magna and Selenastrum capricornutum | Author: Stephenson R.R. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute toxicity mutagenicity and estrogenicity of Bisphenol-A and other Bisphenols | Author: Chen M., Ike M., and Fujita M. | Year: 2002 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Development of Copepod Nauplii to Copepodites - A Parameter For Chronic Toxicity Including Endocrine Disruption | Author: Anderson H.R. et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Fully defined saltwater medium for cultivation of and toxicity testing with marine copepod Acartia Tonsa | Author: Kusk K.O., Wollenberger L. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Estrogenic compounds affect development of harpacticoid copepod Tigriopus japonicus | Author: Marcial H.S., Hagiwara A., and Snell T.W. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: BPA: Acute Toxicity Test (96 hours) with the Giant Ramshorn Snail Marisa cornuarietis determined under static renewal test conditions | Author: Warbritton R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: BPA: Acute Toxicity Test (96 hours) with the Giant Ramshorn Snail Marisa cornuarietis determined under static renewal test conditions | Author: Warbritton R. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A: Acute Toxicity to the Giant Ramshorn Snail Marisa cornuarietis determined under static-renewal test conditions at 22°C | Author: Hughes C. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A: Acute Toxicity to the Giant Ramshorn Snail Marisa cornuarietis determined under static-renewal test conditions at 22°C | Author: Hughes C. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Toxicity of 17-Ethinylestradiol and Bisphenol A to the freshwater cnidarian Hydra vulgaris | Author: Pascoe D. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Survival and precopulatory behaviour of Gammarus pulex (L.) exposed to two xenoestrogens | Author: Watts M.M. Pascoe P. Carroll K. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Toxicity effects of bisphenol A to the nauplii of the brine shrimp Artemia franciscana | Author: Castritsi-Catharios J. et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute toxicity of industrial endocrine-disrupting chemicals natural and synthetic sex hormones to the freshwater planarian Dugesia japonica | Author: Li M.-H. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Bisphenol A: Algal toxicity test | Author: Alexander H.C. et al. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Bisphenol A: Algal toxicity test | Author: Alexander H.C. et al. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Bisphenol A: Acute aquatic toxicity | Author: Alexander H.C. et al. | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Acute Toxicity of Bisphenol A to the Marine Alga Skeletonema costatum | Author: Suprenant D.C. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Acute Toxicity of Bisphenol A to the Marine Alga Skeletonema costatum | Author: Suprenant D.C. | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Diphenylol Propane: Acute Toxicity to Daphnia magna and Selenastrum capricornutum | Author: Stephenson R.R. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Right to refer to study -- Title: Diphenylol Propane: Acute Toxicity to Daphnia magna and Selenastrum capricornutum | Author: Stephenson R.R. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Cellular responses biodegradation and bioaccumulation of endocrine disrupting chemicals in marine diatom Navicula incerta | Author: Liu Y. et al. | Year: 2010 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications | Author: Valéria Gomes Oliveira Falcà et al. | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Analyzing the toxicity of bisphenol-A to microalgae for ecotoxicological applications | Author: Valéria Gomes Oliveira Falcà et al. | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: The effects of bisphenol A F and their mixture on algal and cyanobacterial growth: from additivity to antagonism | Author: Tina Elersek et al. | Year: 2021 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Determination of the acute bacterial toxicity | Author: Fabig W. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. -
Eco-Tox | Toxicity to microorganisms Right to refer to study -- Title: Determination of the acute bacterial toxicity | Author: Fabig W. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Diphenylol Propane: An Assessment of Ready Biodegradability | Author: Stone C.M., Watkinson R.J. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Eco-Tox | Toxicity to microorganisms Right to refer to study -- Title: Diphenylol Propane: An Assessment of Ready Biodegradability | Author: Stone C.M., Watkinson R.J. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Bisphenol A: Partial Life-Cycle Toxicity Test with the Fathead Minnow Pimephales promelas | Author: Rhodes | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Right to refer to study -- Title: Bisphenol A: Partial Life-Cycle Toxicity Test with the Fathead Minnow Pimephales promelas | Author: Rhodes | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Adult fathead minnow Pimephales promelas partial life-cycle reproductive and gonadal histopathology study with bisphenol A. | Author: Mihaich E. et al. | Year: 2012 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Bisphenol A: Effect on the embryo-larval developmental stage of the fathead minnow (Pimephales promelas) | Author: Caunter J.E. et al. | Year: 1999 | Guideline: 210 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Right to refer to study -- Title: Bisphenol A: Effect on the embryo-larval developmental stage of the fathead minnow (Pimephales promelas) | Author: Caunter J.E. et al. | Year: 1999 | Guideline: 210 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Reproductive Effects of Long-Term Exposure to Bisphenol A in the Fathead Minnow (Pimephales promelas) | Author: Sohoni P. et al. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Bisphenol A: Multigeneration study with the Fathead Minnow (Pimephales promelas): a report on the F0 and F1 adult phase | Author: Sumpter J.P., Tyler C.R. Sherazi A. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Right to refer to study -- Title: Bisphenol A: Multigeneration study with the Fathead Minnow (Pimephales promelas): a report on the F0 and F1 adult phase | Author: Sumpter J.P., Tyler C.R. Sherazi A. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Early life-stage and multigeneration toxicity study with bisphenol A and fathead minnows (Pimephales promelas. | Author: Staples C. A. et al. | Year: 2011 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Bisphenol A (BPA) - Full Life-Cycle Toxicity Test with Sheepshead Minnow (Cyprinodon variegatus) Under Flow-Through Conditions Following OPPTS Guideline 850.1500 | Author: York D. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Right to refer to study -- Title: Bisphenol A (BPA) - Full Life-Cycle Toxicity Test with Sheepshead Minnow (Cyprinodon variegatus) Under Flow-Through Conditions Following OPPTS Guideline 850.1500 | Author: York D. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Life-cycle studies with 2 marine species and bisphenol A: The mysid shrimp (Americamysis bahia) and sheepshead minnow (Cyprinodon variegatus) | Author: Mihaich E. et al. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Fish juvenile growth test (Oncorhynchus mykiss) of Bisphenol A | Author: Bayer AG | Year: 1999 | Guideline: 215 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Right to refer to study -- Title: Fish juvenile growth test (Oncorhynchus mykiss) of Bisphenol A | Author: Bayer AG | Year: 1999 | Guideline: 215 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Potencies of estrogenic compounds in in vitro screening assays and in life cycle tests with zebrafish in vivo. | Author: Segner H. et al. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Effect of Bisphenol A on the early life stage in Japanese medaka (Oryzias latipes) | Author: Yokota H. et al. | Year: 2000 | Guideline: 210 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Effects of bisphenol A on the reproduction of Japanese medaka (Oryzias latipes) | Author: Kang I.J. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Estrogenic potency of chemicals detected in sewage treatment plant effluents as determined by in vitro assays with Japanese medaka (Oryzias latipes) | Author: Metcalfe C.D. et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Test Results of Endocrine Disrupting Effects on the Biological System in Fish 37. Bisphenol A Study Results on Medaka (Tentative). July 27 2004 | Author: Japan Ministry of Environment | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Effects of estrogenic and antiandrogenic compounds on the testis structure of the adult guppy (Poecilia reticulata) | Author: Kinnberg K. Toft G. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Bisphenol A induces yolk-sac oedema and other adverse effects in landlocked salmon (Salmo salar m. sebago) yolk-sac fry | Author: Honkanen J.O., Holopainen I.J., and Kukkonen J.V.K. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to fish Robust Study Summary -- Title: Toxic effects of bisphenol A on early life stages of Japanese medaka (Oryzias latipes) | Author: Sun L. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Life-cycle studies with 2 marine species and bisphenol A: The mysid shrimp (Americamysis bahia) and sheepshead minnow (Cyprinodon variegatus) | Author: Mihaich E. et al. | Year: 2018 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A - Life-Cycle Toxicity Test with Mysids (Americamysis bahia) Following Draft OPPTS Guideline 850.1350 | Author: Lee M. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A - Life-Cycle Toxicity Test with Mysids (Americamysis bahia) Following Draft OPPTS Guideline 850.1350 | Author: Lee M. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: No Estrogenic Effects of Bisphenol A in Daphnia magna STRAUS | Author: Caspers N. | Year: 1998 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: No Estrogenic Effects of Bisphenol A in Daphnia magna STRAUS | Author: Caspers N. | Year: 1998 | Guideline: 211 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A: Effects on Fecundity Hatchability and Growth of Marisa cornuarietis under flow-through conditions at twenty-five degrees celsius (Phase III Definitive Toxicity Test) | Author: Warbritton R., Forbes V.E., and Van der Hoeven N. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A: Effects on Fecundity Hatchability and Growth of Marisa cornuarietis under flow-through conditions at twenty-five degrees celsius (Phase III Definitive Toxicity Test) | Author: Warbritton R., Forbes V.E., and Van der Hoeven N. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Effects of bisphenol A on fecundity egg hatchability and juvenile growth of Marisa cornuarietis | Author: Forbes V.E. et al. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Effects of bisphenol A on fecundity egg hatchability and juvenile growth of Marisa cornuarietis | Author: Forbes V.E. et al. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Effects of husbandry parameters on the life-history traits of the apple snail Marisa cornuarietis: effects of temperature photoperiod and population density | Author: Aufderheide J. et al. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Does bisphenol a induce superfeminization in Marisa cornuarietis? Part I: Intra- and inter-laboratory variability in test endpoints | Author: Forbes V.E. et al. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Does bisphenol A induce superfeminization in Marisa cornuarietis? Part II: Toxicity test results and requirements for statistical power analyses | Author: Forbes V.E. et al. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Effects of food type feeding frequency and temperature on juvenile survival and growth of Marisa cornuarietis (Mollusca: Gastropods) | Author: Selck H. et al. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A: Effects on Fecundity Hatchability and Growth of Marisa cornuarietis Under Flow-Through Conditions at Twenty-Five Degrees Celsius | Author: Warbritton R., Forbes V., and van der Hoeven N. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A: Effects on Fecundity Hatchability and Growth of Marisa cornuarietis Under Flow-Through Conditions at Twenty-Five Degrees Celsius | Author: Warbritton R., Forbes V., and van der Hoeven N. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A (BPA) - Chronic Toxicity to Amphipods (Hyalella azteca) Under Flow-Through Conditions | Author: Cafarella M. A. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A (BPA) - Chronic Toxicity to Amphipods (Hyalella azteca) Under Flow-Through Conditions | Author: Cafarella M. A. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute and chronic toxicity testing of bisphenol A with aquatic invertebrates and plants. | Author: Mihaich E.M. et al. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A (BPA) - Chronic Toxicity to Rotifers (Brachionus calyciflorus) Under Static Conditions | Author: Sayers L.E. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Right to refer to study -- Title: Bisphenol A (BPA) - Chronic Toxicity to Rotifers (Brachionus calyciflorus) Under Static Conditions | Author: Sayers L.E. | Year: 2006 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Bisphenol A migration from plastic materials: direct insight of ecotoxicity in Daphnia magna. | Author: Mansilha C. et al. | Year: 2013 | Guideline: 211 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Multi-generational effects of four selected environmental oestrogens on Daphnia magna | Author: Brennan S.J. et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Covert signal disruption: anti-ecdysteroidal activity of Bisphenol A involves cross-talk between signaling pathways | Author: Mu X. et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Toxicity of 17-Ethinylestradiol and Bisphenol A to the freshwater cnidarian Hydra vulgaris | Author: Pascoe D. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Toxic effects of endocrine disrupters on freshwater sponges: common developmental abnormalities | Author: Hill M. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Antioxidant responses and whole-organism changes in Daphnia magna acutely and chronically exposed to endocrine disruptor bisphenol A | Author: Jemec A. et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Exposure to 17[α]-ethinylestradiol and bisphenol A – effects on larval moulting and mouthpart structure of Chironomus riparius | Author: Watts M.M., Pascoe D. and Carroll K. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Reproductive toxicity of bisphenol A and cadmium in Potamopyrgus antipodarum and modulation of bisphenol A effects by different test temperature | Author: Sieratowicz A. et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Adverse effects of bisphenol A on water louse (Asellus aquaticus) | Author: Plahuta M. et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Long-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Chronic toxicity of endocrine disrupting chemicals used in plastic products in Korean resident species: Implications for aquatic ecological risk assessment | Author: Jae-Woong Jung et al. | Year: 2020 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Experiences with the test scheme under the chemical control law of Japan: An approach to structure-activity correlations | Author: Kawasaki M. | Year: 1980 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Data of existing chemicals based on the CSCL Japan: Biodegradation and bioaccumulation | Author: MITI | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Bisphenol A and nonylphenol bioconcentration in spotted halibut Varaspar variegates | Author: Lee H.C. et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Uptake metabolism and excretion of bisphenol A in the rainbow trout (Oncorhynchus mykiss) | Author: Lindholst C., Pedersen S.N., and Bjerregaard P. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Bioconcentration factor of bisphenol A for killifish (Oryzias latipes) | Author: Takino A. et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Bisphenol A accumulation in the freshwater clam Pisidium Amnicum at low temperatures | Author: Heinonen J. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Fish bile used to detect estrogenic substances in treated sewage water | Author: Pettersson M. et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Bioaccumulation: aquatic/sediment Robust Study Summary -- Title: Fates and transport of PPCPs in soil receiving reclaimed water irrigation | Author: Chen W. et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Eco-Tox | Toxicity to other aquatic vertebrates Robust Study Summary -- Title: Bisphenol A: Determination of Effects on Larval Growth Development and Sexual Differentiation of the African Clawed Frog (Xenopus laevis) | Author: Pickford D.B. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to other aquatic vertebrates Right to refer to study -- Title: Bisphenol A: Determination of Effects on Larval Growth Development and Sexual Differentiation of the African Clawed Frog (Xenopus laevis) | Author: Pickford D.B. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to other aquatic vertebrates Robust Study Summary -- Title: Assessing chronic toxicity of bisphenol A to larvae of the African clawed frog (Xenopus laevis) in a flow-through exposure system | Author: Pickford D.B. et al. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to other aquatic vertebrates Robust Study Summary -- Title: Stage-dependent toxicity of bisphenol A on Rhinella arenarum (anura bufonidae) embryos and larvae. | Author: Hutler Wolkowicz I.R., Herkovits J., and Pérez Coll C.S. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Sediment toxicity Robust Study Summary -- Title: CHARACTERIZING THE EFFECTS OF BISPHENOL A ON SEDIMENT DWELLING BENTHIC ORGANISMS | Author: Staples C. et al. | Year: 2016 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Robust Study Summary -- Title: Bisphenol A - 28-Day Toxicity Test Exposing Estuarine Amphipods (Leptocheirus plumulosus) to a Test Substance Applied to Sediment Following EPA Test Methods | Author: Picard C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Right to refer to study -- Title: Bisphenol A - 28-Day Toxicity Test Exposing Estuarine Amphipods (Leptocheirus plumulosus) to a Test Substance Applied to Sediment Following EPA Test Methods | Author: Picard C. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Robust Study Summary -- Title: Bisphenol A - Sediment-Water Lumbriculus Toxicity Test Using Spiked Sediment Following OECD Guideline 225 | Author: Picard C. | Year: 2010 | Guideline: 225 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Right to refer to study -- Title: Bisphenol A - Sediment-Water Lumbriculus Toxicity Test Using Spiked Sediment Following OECD Guideline 225 | Author: Picard C. | Year: 2010 | Guideline: 225 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Robust Study Summary -- Title: Bisphenol A - Toxicity Test with Sediment-Dwelling Midges (Chironomus riparius) Under Static-Renewal Conditions Following OECD Guideline 218 | Author: Picard C. | Year: 2010 | Guideline: 218 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Right to refer to study -- Title: Bisphenol A - Toxicity Test with Sediment-Dwelling Midges (Chironomus riparius) Under Static-Renewal Conditions Following OECD Guideline 218 | Author: Picard C. | Year: 2010 | Guideline: 218 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Sediment toxicity Robust Study Summary -- Title: Bisphenol A: Toxicity in marine sediments to Corophium volutator | Author: Whale G.F., Worden J.R., and Bumpus R.N. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eco-Tox | Sediment toxicity Right to refer to study -- Title: Bisphenol A: Toxicity in marine sediments to Corophium volutator | Author: Whale G.F., Worden J.R., and Bumpus R.N. | Year: 1999 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Eco-Tox | Toxicity to aquatic plants other than algae Robust Study Summary -- Title: Bisphenol A - 7-Day Toxicity To Duckweed Lemna gibba Under Static-Renewal Conditions | Author: Putt A. | Year: 2003 | Guideline: 221 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic plants other than algae Right to refer to study -- Title: Bisphenol A - 7-Day Toxicity To Duckweed Lemna gibba Under Static-Renewal Conditions | Author: Putt A. | Year: 2003 | Guideline: 221 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to aquatic plants other than algae Robust Study Summary -- Title: Acute and chronic toxicity testing of bisphenol A with aquatic invertebrates and plants. | Author: Mihaich E.M. et al. | Year: 2009 | Guideline: 221 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to soil macro-organisms except arthropods Robust Study Summary -- Title: Bisphenol A: Reproduction toxicity to the enchytraeid species Enchytraeus crypticus in artificial soil according to the OECD Guideline No. 220 | Author: Moser T., Egeler P. | Year: 2007 | Guideline: 220 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to soil macro-organisms except arthropods Right to refer to study -- Title: Bisphenol A: Reproduction toxicity to the enchytraeid species Enchytraeus crypticus in artificial soil according to the OECD Guideline No. 220 | Author: Moser T., Egeler P. | Year: 2007 | Guideline: 220 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to soil macro-organisms except arthropods Robust Study Summary -- Title: Estimating potential risks to terrestrial invertebrates and plants exposed to bisphenol A in soil amended with activated sludge biosolids | Author: Staples C.A. et al. | Year: 2010 | Guideline: 220 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial plants Robust Study Summary -- Title: Bisphenol A - Determination of Effects on Seedling Emergence and Seedling Growth (Definitive Tests) | Author: Hoberg J. | Year: 2007 | Guideline: 208 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial plants Right to refer to study -- Title: Bisphenol A - Determination of Effects on Seedling Emergence and Seedling Growth (Definitive Tests) | Author: Hoberg J. | Year: 2007 | Guideline: 208 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial plants Robust Study Summary -- Title: Estimating potential risks to terrestrial invertebrates and plants exposed to bisphenol A in soil amended with activated sludge biosolids | Author: Staples C.A. et al. | Year: 2010 | Guideline: 208 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial plants Robust Study Summary -- Title: Uptake and accumulation of four PPCP/EDCs in two leafy vegetables | Author: Dodgen L.K. et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to soil microorganisms Robust Study Summary -- Title: Bisphenol A: A Reproduction study with the Japanese quail | Author: Frey L.T. et al. | Year: 2010 | Guideline: 206 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to soil microorganisms Robust Study Summary -- Title: Distribution of bisphenol A and tetrabromobisphenol A in quail eggs embryos and laying birds and studies on reproduction variables in adults following in ovo exposure | Author: Halldin K. et al. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to soil microorganisms Robust Study Summary -- Title: Effects of Intrayolk Injection of Bisphenol A on Hatchability and Sex Ratio in Chickens | Author: Sashihara K. et al. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to soil microorganisms Robust Study Summary -- Title: Effects of Bisphenol A and Tetrabromobisphenol A on Sex Organ Development in Quail and Chicken Embryos | Author: Berg C., Halldin K., and Brunstrom B. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Eco-Tox | Toxicity to terrestrial arthropods Robust Study Summary -- Title: Bisphenol A: Reproduction toxicity to the collembolan species Folsomia candida in artificial soil according to the International Standard ISO 11267 (1999) | Author: Moser T., Egeler P. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial arthropods Right to refer to study -- Title: Bisphenol A: Reproduction toxicity to the collembolan species Folsomia candida in artificial soil according to the International Standard ISO 11267 (1999) | Author: Moser T., Egeler P. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Toxicity to terrestrial arthropods Robust Study Summary -- Title: Estimating potential risks to terrestrial invertebrates and plants exposed to bisphenol A in soil amended with activated sludge biosolids | Author: Staples C.A. et al. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Endocrine disrupter testing in aquatic vertebrates - in vivo Robust Study Summary -- Title: Bisphenol A induces a shift in sex differentiation gene expression with testis-ova or sex reversal in Japanese medaka (Oryzias latipes) | Author: Horie Y. et al. | Year: 2019 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Assessment of the ready biodegradability of bisphenol A | Author: West R.J., Goodwin P.A., and Klecka G.M. | Year: 2001 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Assessment of the ready biodegradability of bisphenol A | Author: West R.J., Goodwin P.A., and Klecka G.M. | Year: 2001 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Evaluation of ready biodegradability of bisphenol A using the OECD Method 301D: Manometric Respirometry | Author: West R.J. | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Evaluation of ready biodegradability of bisphenol A using the OECD Method 301D: Manometric Respirometry | Author: West R.J. | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Evaluation of ready biodegradability of bisphenol A using the OECD Method 301D: Manometric Respirometry (22+-1C) | Author: West R.J. | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Evaluation of ready biodegradability of bisphenol A using the OECD Method 301D: Manometric Respirometry (22+-1C) | Author: West R.J. | Year: 1997 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation Study of Bisphenol A by Microorganisms | Author: Katagiri K. | Year: 2004 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Biodegradation Study of Bisphenol A by Microorganisms | Author: Katagiri K. | Year: 2004 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Diphenylol Propane: An Assessment of Ready Biodegradability | Author: Stone C.M., Watkinson R.J. | Year: 1983 | Guideline: 301D | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Diphenylol Propane: An Assessment of Ready Biodegradability | Author: Stone C.M., Watkinson R.J. | Year: 1983 | Guideline: 301D | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation study | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Biodegradation study | Author: Bayer AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Diphenylol propane: an assessment of inherent biodegradability | Author: Turner S.J., Watkinson R.J. | Year: 1986 | Guideline: 302A | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Diphenylol propane: an assessment of inherent biodegradability | Author: Turner S.J., Watkinson R.J. | Year: 1986 | Guideline: 302A | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Fate of 14C-bisphenol A in soils | Author: Fent G. et al. | Year: 2003 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Adsorption/desorption Right to refer to study -- Title: Fate of 14C-bisphenol A in soils | Author: Fent G. et al. | Year: 2003 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Sorption and dialysis experiments to assess the binding of phenolic xenobiotics to dissolved organic matter in soil | Author: Hollringl-Rosta A. et al. | Year: 2003 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Sorption and degradation of estrogen-like-endocrine disrupting chemicals in soil | Author: Ying G-G, Kookana R.S. | Year: 2005 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Sorption and degradation of five selected endocrine disrupting materials in aquifer materials | Author: Ying G-G, Kookana R.S., and Dillon P. | Year: 2003 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Fate of anthropogenic orvanic pollutants in soils with emphasis on adsorption/desorption processes of endocrine disruptor compounds | Author: Loffredo E. Senesi N. | Year: 2006 | Guideline: 106 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Adsorption behavior of bisphenol A on sediments in Xiangjiang RIver south-central China | Author: Zeng G. et al. | Year: 2006 | Guideline: 106 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Adsorption of bisphenol-A 17B-estradiole and 17A-ethinylestradiole to sewage sludge | Author: Clara M. et al. | Year: 2004 | Guideline: 106 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Fates and transport of PPCPs in soil receiving reclaimed water irrigation | Author: Chen W.et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Biodegradation of Bisphenol A in Aquatic Environments - River Die-Away | Author: Klecka G.M. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water and sediment: simulation tests Right to refer to study -- Title: Biodegradation of Bisphenol A in Aquatic Environments - River Die-Away | Author: Klecka G.M. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Biodegradation of bisphenol A in aquatic environments: River die-away | Author: Klecka G.M. et al. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Effects of bacterial counts and temperature on the biodegradation of bisphenol A in river water | Author: Kang J.H., Kondo F. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Degradation of five selected endocrine-disrupting chemicals in seawater and marine sediment | Author: Ying G.G., Kookana R.S. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Laboratory degradation studies of four endocrine disruptors in two environmental media | Author: Sarmah A.K., Northcott G.L. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Degradation of bisphenol A in natural waters | Author: Dorn P.B., Chou C-S, and Gentempo J.J. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Environmental fate of bisphenol A and its biological metabolites in river water and their xeno-estrogenic activity | Author: Suzuki T. et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Biodegradation of bisphenol A in the aquatic environment | Author: Ike M., Jin C.S., and Fujita M. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Biodegradation of a variety of bisphenols under aerobic and anaerobic conditions | Author: Ike M. et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Bisphenol A degradation in seawater is different from that in river water | Author: Kang J-H Kondo F. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Treatment of wastewater containing bisphenol A | Author: Furun L., Boqing L., and Zheyong S. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Experience of 16 years operation and maintenance of the Kashima petrochemical complex. II. Biodegradability of 37 organic substances and 28 process wastewaters. Water Science Technology. 20: 201-210 | Author: Matsui S., Okawa Y., and Ota R. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Streptomyces sp. strain isolated from river water has high bisphenol A degradability | Author: Kang J-H, Ri N., and Kondo F. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Anaerobic biotransformation of tetrabromobisphenol A tetrachlorobisphenol A and bisphenol A in estuarine sediments | Author: Voordeckers J.W. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Enrichment of a microbial culture capable of reductive debromination of the flame retardant tetrabromobisphenol-A and identification of the intermediate metabolites produced in the process | Author: Arbeli Z. Ronen Z. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Biodegradation of bisphenol-A and other bisphenols by a gram-negative aerobic bacterium | Author: Lobos J.H., Leib T.K., and Su T-M | Year: 1992 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Novel pathway for bacterial metabolism of bisphenol A | Author: Spivack J., Leib T.K., and Lobos J.H. | Year: 1994 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Microbial metabolism of the environmental estrogen bisphenol A | Author: Yim S.H., Kim H.J., and Lee I.S. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Metabolic pathway of bisphenol A by Pseudomonas paucimobilis strain FJ-4 | Author: Jin C. Ike M. Fujita M. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Estrogen activity increased in the process of biodegradation of bisphenol A | Author: Ohtani Y. et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Variation of estrogenic activities during the bio-degradation of bisphenol A | Author: Ohtani Y. et al. | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Salt marsh rhizosphere affects microbial biotransformation of the widespread halogenated contaminant tetrabromobisphenol-A (TBBPA) | Author: Ravit B., Ehrenfeld J.G., and Haggblom M.M. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Anaerobic-aerobic process for microbial degradation of tetrabromobisphenol A | Author: Ronen Z. Abeliovich A. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Robust Study Summary -- Title: Bisphenol A: Degradation Kinetics and Removal in a Continuous Activated Sludge (CAS) Simulation Test (OECD 303A) | Author: Hanstveit I.R., Aslderink I.G.H. | Year: 2001 | Guideline: 303A | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Biodegradation in water and sediment: simulation tests Right to refer to study -- Title: Bisphenol A: Degradation Kinetics and Removal in a Continuous Activated Sludge (CAS) Simulation Test (OECD 303A) | Author: Hanstveit I.R., Aslderink I.G.H. | Year: 2001 | Guideline: 303A | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: Fate of 14C-bisphenol A in soils | Author: Fent G. et al. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Other distribution data Robust Study Summary -- Title: Sorption and degradation of estrogen-like-endocrine disrupting chemicals in soil | Author: Ying G-G, Kookana R.S. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: Sorption and degradation of five selected endocrine disrupting materials in aquifer materials | Author: Ying G-G, Kookana R.S., and Dillon P. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: A multimedia assessment of the environmental fate of bisphenol A | Author: Cousins I.T. et al. | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Other distribution data Robust Study Summary -- Title: EPISuite v3.12 | Author: EPA | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: ECOBASE Data collected by den Haan KH and de Snoo TJJ | Author: Shell Group | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Other distribution data Right to refer to study -- Title: ECOBASE Data collected by den Haan KH and de Snoo TJJ | Author: Shell Group | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: Numerical simulation of organic chemicals in a marine environment using a coupled 3D hydrodynamic and ecotoxicological model | Author: Kim D-M et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Other distribution data Robust Study Summary -- Title: Evaluation and comparison of multimedia mass balance models of chemical fate: application of EUSES and ChemCAN to 68 chemicals in Japan | Author: Kawamoto K., MacLeod M., and Mackay D. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Environmental | Phototransformation in air Robust Study Summary -- Title: 4,4'-Isopropylidenediphenol (bisphenol-A) | Author: EC | Year: 2003 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Environmental | Phototransformation in water Robust Study Summary -- Title: Photosensitized degradation of bisphenol A by dissolved organic matter | Author: Chin Y.P. et al. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. -
Environmental | Phototransformation in water Robust Study Summary -- Title: Photosensitized degradation of bisphenol A involving reactive oxygen species in the presence of humic substances | Author: Zhan M. et al. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Phototransformation in water Robust Study Summary -- Title: Photochemical transformations of tetrabromobisphenol A and related phenols in water | Author: Eriksson J. et al. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in soil Robust Study Summary -- Title: Fate of 14C-bisphenol A in soils | Author: Fent G. et al. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in soil Robust Study Summary -- Title: Sorption and degradation of estrogen-like-endocrine disrupting chemicals in soil | Author: Ying G-G, Kookana R.S. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Biodegradation in soil Robust Study Summary -- Title: Sorption and degradation of five selected endocrine disrupting materials in aquifer materials | Author: Ying G-G, Kookana R.S., and Dillon P. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. -
Environmental | Monitoring data Robust Study Summary -- Title: Exposure analysis of bisphenol A in surface water systems in North America and Europe | Author: Klecka G.M. et al. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Right to refer to study -- Title: Exposure analysis of bisphenol A in surface water systems in North America and Europe | Author: Klecka G.M. et al. | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Pharmaceuticals hormones and other organic wastewater contaminants in U.S. streams 1999-2000: A national reconnaissance | Author: Kolpin D.W. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Bisphenol A concentrations in receiving waters near US manufacturing and processing facilities | Author: Staples C.A. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Right to refer to study -- Title: Bisphenol A concentrations in receiving waters near US manufacturing and processing facilities | Author: Staples C.A. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Estrogens and Xenoestrogens in the Aquatic Environment of The Netherlands | Author: Vethaak A.D. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Right to refer to study -- Title: Estrogens and Xenoestrogens in the Aquatic Environment of The Netherlands | Author: Vethaak A.D. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: An integrated assessment of estrogenic contamination and biological effects in the aquatic environment of The Netherlands | Author: Vethaak A.D. et al. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: The occurrence of xenostrogens in the Elbe River and the North Sea | Author: Heemken O.P. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Endocrine disrupters in the aquatic environment: the Austrian approach - ARCEM | Author: Bursch W. et al. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Monitoring of selected estrogenic hormones and industrial chemicals in groundwaters and surface waters in Austria | Author: Hohenblum P. et al. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: The report on monitoring of endocrine distruptors in the environment (The first half of the survey) | Author: Japanese Ministry of Construction | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Identification of organic compounds and ecotoxicological assessment of sewage treatment plants (STP) effluents | Author: Aguayo S. et al. | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Substances with Estrogenic Activity in Effluents of Sewage Treatment Plants in Southwestern Germany. 1. Chemical Analysis | Author: Spengler P., Korner W. And Metzger J.W. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: An Assessment of Endocrine Disrupting Activity Changes during Wastewater Treatment through the Use of Bioassays and Chemical Measurements | Author: Drewes J.E. et al. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Determination of endocrine-disrupting phenols acidic pharmaceuticals and personal-care products in sewage by solid-phase extraction and gas chromatography-mass spectrometry | Author: Lee H-B, Peart T.E., and Svoboda M.L. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Bisphenol A: emissions from point sources | Author: Fuerhacker M., Scharf S., and Weber H. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Input/output balance of estrogenic active compounds in a major municipal sewage plant in Germany | Author: Korner W. et al. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Removal of selected pharmaceuticals fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants | Author: Clara M. et al. | Year: 2005 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Occurrence of phthalates and bisphenol A and F in the environment | Author: Fromme H. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Relevance of drinking water as a source of human exposure to bisphenol A | Author: Arnold S.M. et al. | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Environmental | Monitoring data Robust Study Summary -- Title: Pressurized liquid extraction using water/isopropanol coupled with solid-phase extraction cleanup for industrial and anthropogenic waste-indicator compounds in sediment | Author: Burkhardt M.R. et al. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
RSS and access rights to the underlying studies. The price offered gives restricted access for registration purposes under Turkey REACH only.
The offer does not include the right for sublicensing.
For publicly available studies, no access costs have been included and the buyer needs to ensure that they fulfil the requirements for the use of the publication.