You are here: Home> Turkey>TR-REACH>CAS 75-79-6> CAS 75-79-6 | Data Package 10 - 100 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Stability: thermal, sunlight, metals | Robust Study Summary -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Author: CHILWORTH TECHNOLOGY, INC. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Stability: thermal, sunlight, metals | Right to refer to study -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Author: CHILWORTH TECHNOLOGY, INC. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Waiver | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Organochlorosilane A-154 Primary Skin Irritancy Study in the Rabbit. | Author: Bushy Run Research Center | Year: 1989 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Organochlorosilane A-154 Primary Skin Irritancy Study in the Rabbit. | Author: Bushy Run Research Center | Year: 1989 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Flash point test on Trichloromethylsilane | Author: DEFITRACES | Year: 2015 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Flash point test on Trichloromethylsilane | Author: DEFITRACES | Year: 2015 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish); Handbook of Environmental Chemistry. | Author: Hazleton; Chandra, G. | Year: 1994; 1997 | Guideline: C.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Brachydanio rerio (Zebra fish); Handbook of Environmental Chemistry. | Author: Hazleton; Chandra, G. | Year: 1994; 1997 | Guideline: C.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton | Year: 1994 | Guideline: C.2 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Silane MI-Triethoxy: Acute Toxicity to Daphnia magna | Author: Hazleton | Year: 1994 | Guideline: C.2 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Silane Ml-Triethoxy: Inhibition of growth to the alga, Selenastrum capricomutum. | Author: Wacker | Year: 1994 | Guideline: C.3 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Silane Ml-Triethoxy: Inhibition of growth to the alga, Selenastrum capricomutum. | Author: Wacker | Year: 1994 | Guideline: C.3 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Guideline: 209 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Waiver | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Test Report | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E659 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Test Report | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E659 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies. | Author: Bushy Run Research Center | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies. | Author: Bushy Run Research Center | Year: 1981 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation; | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation; | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: An Acute Whole Body Inhalation Toxicity Study of Methyltrichlorosilane in Fischer 344 Rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: An Acute Whole Body Inhalation Toxicity Study of Methyltrichlorosilane in Fischer 344 Rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Evaluation of methyltrichlorosilane MeSiCl3 | Author: Litton Bonetics Inc. | Year: 1978 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: NOTOX B.V | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: NOTOX B.V | Year: 2009 | Guideline: A.14 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Vapor Pressures of Silicon Compounds | Author: Jenkins A. C., Chambers G. F. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: (Internal notice) Mitteilung an Abt. E. HRN. J. DICKER: Damfdruckbestimmung | Author: Wacker | Year: 1995 | Guideline: A.4 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: (Internal notice) Mitteilung an Abt. E. HRN. J. DICKER: Damfdruckbestimmung | Author: Wacker | Year: 1995 | Guideline: A.4 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the density of trichloro(methyl)silane; QSAR Model Reporting Format: Prediction of density based on structural contributions Version 3 | Author: Peter Fisk Associates | Year: 2022; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the density of trichloro(methyl)silane; QSAR Model Reporting Format: Prediction of density based on structural contributions Version 3 | Author: Peter Fisk Associates | Year: 2022; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Design Institute for Physical Property Data (DIPPR) ; Methyl Trichlorosilane and its Fluorination Products. | Author: American Institute of Chemical Engineers (AIChE); Booth H S, Martin W F III | Year: 1946 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Flash point test on Trichloromethylsilane | Author: DEFITRACES | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Flash point test on Trichloromethylsilane | Author: DEFITRACES | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Additional physico-chemical information | Robust Study Summary -- Title: MINIMUM IGNITION ENERGY DETERMINATION FOR SEHSC | Author: Chilworth Technology, Inc. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Additional physico-chemical information | Right to refer to study -- Title: MINIMUM IGNITION ENERGY DETERMINATION FOR SEHSC | Author: Chilworth Technology, Inc. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Waiver | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Data on Organic Compounds | Author: Weast R C, Astle M J, eds. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Weast, R. C. (ed.) | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow of methylsilanetriol; QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2. | Author: Peter Fisk Associates | Year: 2015; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow of methylsilanetriol; QSAR Model Reporting Format: KOWWIN v 1.68 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (log Kow) of organosilicon compounds. Version 2. | Author: Peter Fisk Associates | Year: 2015; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor Pressures of Silicon Compounds | Author: Jenkins A. C., Chambers G. F. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Additional physico-chemical information | Robust Study Summary -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Additional physico-chemical information | Right to refer to study -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Trichloromethylsilane salmonella/microsome test to evaluate for point mutagenic effects | Author: Bayer AG | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Trichloromethylsilane salmonella/microsome test to evaluate for point mutagenic effects | Author: Bayer AG | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the water solubility of methylsilanetriol; QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2016; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the water solubility of methylsilanetriol; QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2016; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Assessment of Ready Biodegradability; CO2 in Sealed Vessels (CO2 Headspace Test) | Author: Clarke N. | Year: 2008 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Assessment of Ready Biodegradability; CO2 in Sealed Vessels (CO2 Headspace Test) | Author: Clarke N. | Year: 2008 | Guideline: 310 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Chemical Safety Data Booklet Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silicones Health Council | Year: 1987 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1992 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1992 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Flash point and autoignition temperature of 9 silanes | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM D56 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Flash point and autoignition temperature of 9 silanes | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM D56 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Methyltrichlorosilane CASNR: 75-79-6 | Author: HSDB; | Year: 1981 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
- |
| Environmental | Hydrolysis | Right to refer to study -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
- |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Author: CHILWORTH TECHNOLOGY, INC. | Year: 2001 | Guideline: Carius tube | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: PHYSICAL PROPERTIES DETERMINATION of SILANES | Author: CHILWORTH TECHNOLOGY, INC. | Year: 2001 | Guideline: Carius tube | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1989 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1989 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined repeated dose and reproductive/developmental toxicity screening test of triethoxy(methyl)silane by oral administration in rats | Author: Bozo Research Center | Year: 2012 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Chemical Rubber Company Atlas of Spectral Data and Physical Constants for Organic Compounds | Author: Grasselli J. G., Ritchey W. M. | Year: 1975 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Waiver | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Evaluation of Dow Corning Z-1211 Methyltrichlorosilane in the Ames Bacterial Assay System | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity Evaluation of Dow Corning Z-1211 Methyltrichlorosilane in the Ames Bacterial Assay System | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Design Institute for Physical Property Data (DIPPR) | Author: American Institute of Chemical Engineers (AIChE) | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Eye irritation | Waiver | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Organochlorosilane A-154: Acute Toxicity and Primary Irritancy Studies | Author: Bushy Run Research Center | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physicochemical Properties of Methyl- and Ethlhalosilanes | Author: I. B. Sladkov | Year: 2001 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A two-week repeated dose inhalation toxicity study of hydrogen chloride and selected chlorosilanes in albino rats. | Author: Dow Corning Corporation | Year: 1993 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A two-week repeated dose inhalation toxicity study of hydrogen chloride and selected chlorosilanes in albino rats. | Author: Dow Corning Corporation | Year: 1993 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity evaluation of Methyltrichlorosilane | Author: Litton Bionetics Inc. | Year: 1978 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Guideline: ASTM 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Guideline: ASTM 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Dow Corning Corporation | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. Read-Across (CAS 75-78-5 | EC 200-901-0 | Dichloro(dimethyl)silane) |
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| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Combined repeated dose and reproductive/developmental toxicity screening test of triethoxy(methyl)silane by oral administration in rats | Author: Bozo Research Center | Year: 2012 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Chemical Safety Data Booklet Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silicones Health Council | Year: 1987 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Design Institute for Physical Property Data (DIPPR) | Author: American Institute of Chemical Engineers (AIChE) | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: The Sigma Aldrich Library of Chemical Safety Data, | Author: Sigma Aldrich | Year: 1988 | Guideline: DIN 51755 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Certain Physiochemical Properties of Trichloromethysilane. | Author: Sokolova T D, Prokof'eva N K, Nisel'son L A | Year: 1973 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test for Methyltrimethoxysilane in Sprague-Dawley Rats | Author: Dow Corning Corporation | Year: 2005 | Guideline: 422 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: CRC Press Inc. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: Rhone-Poulenc Chemie | Guideline: DIN 51794 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: No information | Author: Rhone-Poulenc Chemie | Guideline: DIN 51794 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Waiver | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity Evaluation of Hexamethylcyclotrisiloxane (Me2SiO)3: An in vitro cytogenetic assay measuring sister chromatid exchange and chromome aberrations | Author: Litton Bionetics Inc. | Year: 1979 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Fire Protection Guide to Hazardous Materials | Author: National Fire Protection Association | Year: 1997 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mutagenicity evaluation of Methyltrichlorosilane | Author: Litton Bionetics Inc. | Year: 1978 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined repeated dose and reproductive/developmental toxicity screening test of triethoxy(methyl)silane by oral administration in rats | Author: Bozo Research Center | Year: 2012 | Guideline: 422 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Methyltrimethoxysilane: Simulated Rat Gastric Hydrolysis Study | Author: CRL | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Methyltrimethoxysilane: Simulated Rat Gastric Hydrolysis Study | Author: CRL | Year: 2017 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Chemical Safety Data Booklet Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silicones Health Council | Year: 1987 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Vapor Pressure of Pure Substances. | Author: Stull D R | Year: 1947 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Stability Studies of Alkoxysilanes in Aqueous Media | Author: Kallos G J et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Organic Solvents: Physical Properties and Methods of Purification | Author: Riddick, J.A., Bunger, W.B., Sankano, T.K. | Year: 1986 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: SouthWest Research Institutes | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Final Report for|FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681. | Author: SRI | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Final Report for|FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681. | Author: SRI | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of triethoxy(methyl)silane; Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of triethoxy(methyl)silane | Author: Peter Fisk Associates | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of the Hydrolysis Half Life at pH 7 for Di- and Trialkoxysilane Version 2; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 7 of triethoxy(methyl)silane; Prediction of hydrolysis for Si-containing compounds at pH 4, 5 and 9; QSAR Prediction Reporting Format (QPRF) for the hydrolysis at pH 4, pH 5 and pH 9 of triethoxy(methyl)silane | Author: Peter Fisk Associates | Year: 2014; 2017 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Handbook of Fine Chemicals. | Author: Aldrich Chemical Co. | Year: 1988 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | other mutagenicity information | Robust Study Summary -- Title: Mutagenicity evaluation of Methyltrichlorosilane | Author: Litton Bionetics Inc. | Year: 1978 | Guideline: 482 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: CHRIS - Hazardous Chemical Data. Volume II. | Author: U.S. Coast Guard, Department of Transportation | Year: 1984 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Organic Solvents | Author: Riddick J A et al | Year: 1986 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Toxicity and Safe Handling of Liquid Chlorosilanes | Author: Dow Corning Corporation | Year: 1968 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Toxicity and Safe Handling of Liquid Chlorosilanes | Author: Dow Corning Corporation | Year: 1968 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the vapour pressure of methylsilanetriol; QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2021; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the vapour pressure of methylsilanetriol; QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2021; 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: (Internal memo) Zündpunktbestimmung und Flammpunktbestimmung von M1 Silan | Author: Wacker | Year: 2000 | Guideline: A.4 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: (Internal memo) Zündpunktbestimmung und Flammpunktbestimmung von M1 Silan | Author: Wacker | Year: 2000 | Guideline: A.4 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Methyltrichlorosilane and its Fluorination Products. | Author: Booth H S, Martin W F III | Year: 1946 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Chemical Safety Data Booklet Properties and Essential Information for Handling and Use of CHLOROSILANES | Author: Silicones Health Council | Year: 1987 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |