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| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Silan M2 Study of the Mutagenic Potential in strains of Salmonella typhimurium (Ames Test) and Escherichia coli | Author: Wacker | Year: 1987 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: A Four-Week Inhalation Toxicity Study of Dichlorodimethylsilane in the Sprague Dawley Rat | Author: WIL Research | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Dimethyldichlorsilan: Untersuchungen zur akuten oralen toxizität an männlichen und weiblichen Wistar-ratten | Author: Bayer AG | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Dimethyldichlorsilan: Untersuchungen zur akuten oralen toxizität an männlichen und weiblichen Wistar-ratten | Author: Bayer AG | Year: 1990 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: An acute whole body inhalation toxicity study of dimethyldichlorosilane in Fischer 344 rats | Author: Dow Corning Corporation | Year: 1997 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Zündpunktbestimmung von M2 Silan | Author: Bimsner F | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Zündpunktbestimmung von M2 Silan | Author: Bimsner F | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Dampfdruckbestimmung (Vapour Pressure Determiniation) | Author: Haas H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer AG | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Dimethyldichlorosilan: Prüfung auf primär reizende/ätzende wirkung an der kaninchenhaut | Author: Bayer AG | Year: 1984 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Revised report The effect of dimethyldichlorosilane on the incidence of chromosome breaks and aberrations in rat bone marrow cells. | Author: Bioassay systems corporation | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: In vitro percutaneous absorption of 14C-dimethylsilanediol (14C-DMSD) applied in aqueous solution to human skin. | Author: Dow Corning Corporation | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Dermal absorption | Right to refer to study -- Title: In vitro percutaneous absorption of 14C-dimethylsilanediol (14C-DMSD) applied in aqueous solution to human skin. | Author: Dow Corning Corporation | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Dimethylsilanediol (CAS Number 1066-42-8): Freshwater Alga, Pseudokirchneriella subcapitata, Growth Inhibition test | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | trimethoxy(methyl)silane) |
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| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: ACTIVATED SLUDGE RESPIRATION INHIBITION TEST WITH METHYLTRIMETHOXYSILANE | Author: Desmares-Koopmans M J E | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | Trimethoxy(methyl)silane) |
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| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Cladoceran (Daphnia magna) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Dimethylsilanediol: Acute Toxicity to the Rainbow Trout (Oncorhynchus mykiss) Under Static Test Conditions | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol) |
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| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Assessment of Ready Biodegradability | Author: Clarke N | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-40-6 | EC 213-914-1 | Trimethylsilanol) |
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| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: An Oral (Gavage) Prenatal Developmental Toxicity Study of Dimethylsilanediol in Rats | Author: WIL Research | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: An Oral (Gavage) Prenatal Developmental Toxicity Study of Dimethylsilanediol in Rats | Author: WIL Research | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Influence of Silan A1 to Daphnia magna in a reproduction test. | Author: IBACON | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 115-21-9 | EC 204-072-6 | Trichloro(ethyl)silane) |
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| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Influence of Silan A1 to Daphnia magna in a reproduction test. | Author: IBACON | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 115-21-9 | EC 204-072-6 | Trichloro(ethyl)silane) |
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| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Phys-Chem | Density | Robust Study Summary -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions, version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: QSAR Model Reporting Format: Prediction of density based on structural contributions, version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: QSAR Model Reporting Format (Version 1.2): Prediction of the viscosity of chlorosilanes from boiling point | Author: Peter Fisk Associates | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: QSAR Model Reporting Format (Version 1.2): Prediction of the viscosity of chlorosilanes from boiling point | Author: Peter Fisk Associates | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Eco-Tox | Long-term toxicity to fish | Waiver | - |
| Phys-Chem | Oxidising properties | Waiver | - |
| Phys-Chem | Partition coefficient | Waiver | - |
| Toxicological | Repeated dose toxicity: inhalation | Waiver | - |
| Eco-Tox | Sediment toxicity | Waiver | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Phys-Chem | Stability in organic solvents and identity of relevant degradation products | Waiver | - |
| Phys-Chem | Surface tension | Waiver | - |
| Toxicological | Toxicity to reproduction | Waiver | - |
| Eco-Tox | Toxicity to birds | Waiver | - |
| Eco-Tox | Toxicity to soil macro-organisms except arthropods | Waiver | - |
| Eco-Tox | Toxicity to soil microorganisms | Waiver | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Waiver | - |
| Eco-Tox | Toxicity to terrestrial plants | Waiver | - |
| Phys-Chem | Water solubility | Waiver | - |
| Phys-Chem | Flammability | Waiver | - |
| Toxicological | Eye irritation | Waiver | - |
| Phys-Chem | Stability: Dissociation constant | Waiver | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Environmental | Bioaccumulation: aquatic/sediment | Waiver | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Waiver | - |
| Phys-Chem | Explosive properties | Waiver | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Houghton J S | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolytic Stability of Dimethyldichlorosilane Under Conditions Typical of Nose-Only Vapor Inhalation Exposures | Author: Houghton J S | Year: 2013 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: FLAMMABILITY EVALUATIONS OF NINE SELECT SILANE, SILOXANE, AND SILAZANE COMPOUNDS BY ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: ASTM E 681 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Test report | Author: Southwest Research Institute | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies. | Author: Bushy Run Research Center | Year: 1982 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies. | Author: Bushy Run Research Center | Year: 1982 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1987 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: No information | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: No information | Author: Dow Corning Corporation | Year: 1977 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Assessment of the stability of Trimethylchlorosilane and Dimethyldichlorosilane vapour in air | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 75-77-4 | EC 200-900-5 | Chloro(trimethyl)silane) |
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| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Dimethyldichlorsilan salmonella/mikrosomen test zur untersuchung auf punktmutagene wirkung | Author: Bayer | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Dimethyldichlorsilan salmonella/mikrosomen test zur untersuchung auf punktmutagene wirkung | Author: Bayer | Year: 1984 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | other mutagenicity information | Robust Study Summary -- Title: Mutagenicity evaluation of dimethyldichlorosilane Final report revised September 1978 | Author: Litton Bionetics | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Organochlorosilane A-156: Acute toxicity and primary irritancy studies | Author: Bushy Run Research Center | Year: 1982 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: No information | Author: Weast RC | Year: 1969 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Physical Properties Determination of Silanes | Author: Kohn DY | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Safety Data Sheet: Dimethyldichlorosilane | Author: Momentive | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Safety Data Sheet: Wacker Silane M2 version 2.10 | Author: Wacker-Chemie GmbH | Year: 2003 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Safety Data Sheet: Wacker Silane M2 version 2.10 | Author: Wacker-Chemie GmbH | Year: 2003 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. | - |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane) |
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| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of the Explosive Properties of Methyltrichlorosilane | Author: Brekelmans C.J.M | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis of Methyltrimethoxysilane (CAS# 1185-55-3) | Author: Dow Corning Corporation | Year: 2004 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. Read-Across (CAS 1185-55-3 | EC 214-685-0 | Methyltrimethoxysilane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Determination of Dimethoxydimethylsilane at Different pH Values | Author: Weissenfeld, M. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Determination of Dimethoxydimethylsilane at Different pH Values | Author: Weissenfeld, M. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | dimethylsilanediol) |
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| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Combined Repeated Dose Toxicity Study with the Reproductive/Developmental Toxicity Screening Test For Dimethylsilanediol (DMSD), ZMAT 4065555, in Sprague-Dawley Rats via Oral Gavage | Author: Dow Corning Corporation | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 675-62-7 | EC 211-623-4 | Dichloro(methyl)(3,3,3-trifluoropropyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Non-regulated technical study: Hydrolysis screening studies of HPV chlorosilanes- Final report submitted to the Silicones Environmental Health and Safety Council of North America (SEHSC) | Author: Dow Corning | Year: 2001 | Guideline: 111 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 675-62-7 | EC 211-623-4 | Dichloro(methyl)(3,3,3-trifluoropropyl)silane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: DOW Corning non-regulated technical report | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 80-10-4 | EC 201-251-0 | Dichloro(diphenyl)silane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: DOW Corning non-regulated technical report | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 80-10-4 | EC 201-251-0 | Dichloro(diphenyl)silane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of Physico-chemical Properties of Silan CHM (CAS No. 5578-42-7) | Author: Haas H | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 5578-42-7 | EC 226-956-0 | Dichloro(cyclohexyl)methylsilane) |
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| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 75-79-6 | EC 200-902-6 | Trichloro(methyl)silane ) |
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| Environmental | Hydrolysis | Right to refer to study -- Title: Hydrolysis Screening Studies of HPV Chlorosilanes | Author: Dow Corning Corporation | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 75-79-6 | EC 200-902-6 | Trichloro(methyl)silane ) |
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| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: 90-day inhalation toxicity study of hydrogen chloride gas in B6C3F1 mice, Sprague-Dawley rats and Fischer-344 rats. | Author: Toxigenics Inc | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 7647-01-0 | EC 231-595-7 | Hydrogen chloride) |
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| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Study of Biodegradation of Dimethylsilandiol and methylsilanetriol in soil. | Author: Sabourin C L et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in soil | Right to refer to study -- Title: Study of Biodegradation of Dimethylsilandiol and methylsilanetriol in soil. | Author: Sabourin C L et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Biodegradation of Dimethylsilandiol in soils | Author: Sabourin C L et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in soil | Right to refer to study -- Title: Biodegradation of Dimethylsilandiol in soils | Author: Sabourin C L et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Fate of silicone degradation products (silanols) in soil | Author: Lehmann R G, Varaprath S, Frye C L | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Microbial degradation of Dimethylsilanediol in soil | Author: Lehmann R G, Miller J R, Collins H P | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Temperature Dependence of Air/Water, 1-Octanol/Air, 1-Octanol/Water Partitioning Coefficients of Dimethylsilanediol (DMSD) (CAS No: 1066-42-8) | Author: Shihe Xu | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol) |
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| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Temperature Dependence of Air/Water, 1-Octanol/Air, 1-Octanol/Water Partitioning Coefficients of Dimethylsilanediol (DMSD) (CAS No: 1066-42-8) | Author: Shihe Xu | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. Read-Across (CAS 1066-42-8 | EC 213-915-7 | Dimethylsilanediol) |
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| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of MPBPVP v1.42 for the prediction of the vapour pressures of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds | Author: Peter Fisk Associates | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: BEILSTEIN Database | Author: Phys Prop | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physical Properties Database | Author: American Institute of Chemical Engineers (AIChE) | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |