You are here: Home> Taiwan>TW-REACH>CAS 75-56-9> CAS 75-56-9 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Low-Temperature Heat Capacity and Related Thermodynamic Functions of Propylene Oxide | Author: Oetting FL | Year: 1964 | Guideline: 102 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Propylene Oxide: Acute toxicity (Salmo Gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Propylene Oxide: Acute toxicity (Salmo Gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Medchem Project | Author: Hansch C and Leo AJ | Year: 1989 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Quantitative Structure-Activity Relationship for the Acute Toxicity of Some Epoxy Compounds to the Guppy. | Author: Deneer JW Sinnige TL Seinen W and Hermens JLM | Year: 1988 | Guideline: 107/117/122/123 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of general physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: A.15-16 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of hazardous physico-chemical properties | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: A.15-16 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and bioaccumulation testing results on existing chemical substances. | Author: MITI (Ministry of International Trade and Industry) Japan | Year: 1988 | Guideline: 301 A-F | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Propylene oxide: an assessment of ready biodegradability | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Propylene oxide: an assessment of ready biodegradability | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301 A-F | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Propylene oxide: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Propylene oxide: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Propylene oxide: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Propylene oxide: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Ltd. | Year: 1986 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: A collaborative exercise in acute oral toxicity testing | Author: Shell Research Ltd. | Year: 1968 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: A collaborative exercise in acute oral toxicity testing | Author: Shell Research Ltd. | Year: 1968 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Toxicity studies on propyle oxide: acute inhalation toxicity and 10 day repeated exposure study | Author: Shell Research Ltd. | Year: 1977 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Toxicity studies on propyle oxide: acute inhalation toxicity and 10 day repeated exposure study | Author: Shell Research Ltd. | Year: 1977 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Range finding toxicity data. (List VII). | Author: Smyth HF et al. | Year: 1969 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute dermal irritation in the rabbit | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute dermal irritation in the rabbit | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: propylene oxide: in vitro skin corrosion in the Episkin reconstituted human epidermis model | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: propylene oxide: in vitro skin corrosion in the Episkin reconstituted human epidermis model | Author: Harlan Laboratories Ltd. | Year: 2010 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Propylene Oxide: Skin Sensitization Potential | Author: Dow Chemical Company | Year: 1982 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Propylene Oxide: Skin Sensitization Potential | Author: Dow Chemical Company | Year: 1982 | Guideline: 406, 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Short-term mutation test with industrial chemicals: propylene oxide. | Author: Shell Research Ltd. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Short-term mutation test with industrial chemicals: propylene oxide. | Author: Shell Research Ltd. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Comparative mutagenicity of aliphatic epoxides in Salmonella | Author: Canter DA et al. | Year: 1986 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Short-term mutation test with industrial chemicals: propylene oxide. | Author: Shell Research Ltd. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro genetic toxicity | Right to refer to study -- Title: Short-term mutation test with industrial chemicals: propylene oxide. | Author: Shell Research Ltd. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapours. | Author: McGregor D et al. | Year: 1991 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro III: results with 27 chemicals. | Author: Gulati DK; Witt K; Anderson B; Zeiger E; Shelby MD | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: DNA Adducts Hemoglobin Adducts Abasic Sites and Cell Proliferation in Rats and Mice Exposed to Propylene Oxide by Inhalation. | Author: Swenberg JA et al. I Nakamura J Schoonhoven R and Upton PB | Year: 2006 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Mutagenic activity of propylene oxide in bacterial and mammalian systems | Author: Bootman J Lodge DC and Whalley HE | Year: 1979 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Propylene oxide: Genotoxicity profile of a rodent nasal carcinogen | Author: Albertini RJ and Sweeney LM | Year: 2007 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: The response of germ cell s to Ethylene oxide propylene oxide propylene imine and methyl methanesulfonate is a matter of cell stage-related DNArepair. | Author: Vogel EW and Nivard MJ | Year: 1997 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Sister-chromatid exchanges and chromosome aberrations in lymphocytes from monkeys exposed to ethylene oxide and propylene oxide by inhalation. | Author: Lynch DW et al. | Year: 1984 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Genotoxic effects of inhaled ethylene oxide propylene oxide and butylene oxide on germ cells: sensitivity of genetic endpoints in relation to dose and repair status | Author: Vogel EW and Nivard MJ | Year: 1998 | Guideline: 483 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |