CAS 75-35-4 | TR-REACH

Includes:

Study name	Short Description	Data Owner
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Budavari S \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Budavari S \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Lewis R.J. Sr (Ed.) \| Year: 1997 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: No information \| Author: ECHA \| Year: 2012 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: HENRYWIN v3.20 \| Author: HENRYWIN \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: Interphase transfer processes. II. Evaporation rates of Chloro Methanes Ethanes Ethylenes Propanes and Propylenes from dilute aqueous solutions. Comparaison with theorical predctions. \| Author: Dilling W.L. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: WVOLNT.EXE \| Author: WVOLNT \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Solubilities of Vinyl Chloride and Vinylidene Chloride in Water \| Author: DeLassus P. and Schmidt D.D. \| Year: 1981 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Octanol-water Partition coefficients \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Viscosity of Liquid \| Author: Yaws Carl L. \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Table 5.16 Viscosity and Surface Tension of Various Organic Substances \| Author: Dean J.A. \| Year: 1999 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Solubility in organic solvents/fat solubility	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Solubility in organic solvents/fat solubility	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Flammability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: vinylidene chloride \| Author: Lewis Richard J. Sr. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Flammability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Flamability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Skin irritation / corrosion	*Robust Study Summary* -- Title: IN VITRO SKIN CORROSION: HUMAN SKIN MODEL TEST WITH 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Right to refer to study* -- Title: IN VITRO SKIN CORROSION: HUMAN SKIN MODEL TEST WITH 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Robust Study Summary* -- Title: In vitro skin irritation test:human skin model test with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Right to refer to study* -- Title: In vitro skin irritation test:human skin model test with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Eye irritation	*Robust Study Summary* -- Title: Bovine Corneal Opacity and Permeability Assay (BCOP) with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Eye irritation	*Right to refer to study* -- Title: Bovine Corneal Opacity and Permeability Assay (BCOP) with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin sensitisation	*Robust Study Summary* -- Title: Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay \| Author: Warbrick E.V. et al. \| Year: 2001 \| Guideline: 429 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium \| Author: Bartsch H. et al. \| Year: 1975 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Validation and comparative studies on 180 chemicals with S. thyphimurium strains and V79 chinese hamster cells in the presence of various metabolizing systems \| Author: Bartsch H. et al. \| Year: 1980 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in mammalian cells	*Robust Study Summary* -- Title: Responses of the L5178Y Mouse Lymphoma Forward Mutation Assay: V. Gases and Vapors \| Author: Mc Gregor D. et al. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in mammalian cells	*Robust Study Summary* -- Title: Validation and comparative studies on 180 chemicals with S. thyphimurium strains and V79 chinese hamster cells in the presence of various metabolizing systems \| Author: Bartsch H. et al. \| Year: 1980 \| Guideline: 476 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodents for 16 halogenated aliphatic hydrocarbons \| Author: Roldan-Arjona T. et al. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation \| Author: Greim H. et al. \| Year: 1975 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Genetic effects of chlorinated ethylenes in the yeast Saccharomyces cerevisiae \| Author: Koch R., Schlegelmich R. and Wolf H.U. \| Year: 1988 \| Guideline: 481 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: The induction of mitotic chromosome malsegregation in Aspergillus nidulans. Quantitative structure activity relationship (QSAR) analysis with chlorinated aliphatic hydrocarbons \| Author: Crebelli R. et al. \| Year: 1992 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro cytogenicity study in mammalian cells (CA)	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 473 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro cytogenicity study in mammalian cells (CA)	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 479 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 474 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2013 \| Guideline: 474 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: A dominant lethal study in male rats after repeated exposures to vinyl chloride or vinylidene chloride \| Author: Short R.D. et al. \| Year: 1977 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Current status of bioassays in genetic toxicology - the dominant lethal assay \| Author: Green S. et al. \| Year: 1985 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Dominant Lethal Studies with the Halogenated Olefins Vinyl Chloride and Vinylidene Dichloride in Male CD-1 Mice \| Author: Anderson D, Hodge M.C.E., and Purchase I.F.H. \| Year: 1977 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 Coded Compounds Tested for the National Toxicology Program \| Author: Foureman P. et al. \| Year: 1994 \| Guideline: 477 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Effects of Vinylidene Chloride on DNA Synthesis and DNA Repair in the Rat and Mouse: A Comparative Study with Dimethylnitrosamine \| Author: Reitz R.H. et al. \| Year: 1980 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2013 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: The alkaline in vivo comet assay with 1,1-dichloroethylene in lung liver kidney and bone marrow of Wistar Han rats after nose only inhalation exposure \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Genetic toxicity in vivo	*Right to refer to study* -- Title: The alkaline in vivo comet assay with 1,1-dichloroethylene in lung liver kidney and bone marrow of Wistar Han rats after nose only inhalation exposure \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Acute toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylchlorid bei 4 stüdiger Exposition an NMRI-Mäusen (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylchlorid bei 4 stüdiger Exposition an NMRI-Mäusen (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4 stündiger Exposition an chinesischen Streifenhamstern (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4 stündiger Exposition an chinesischen Streifenhamstern (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4stündiger Exposition an chinesischen Streifenhamstern (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4-stündiger Exposition an chinesischen Streifenhamstern (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: The biological fate of vinylidene chloride in rats \| Author: Jones B.K. and Hathway D.E. \| Year: 1978 \| Guideline: 417 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene \| Author: Dowsley T.F. et al. \| Year: 1995 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Metabolism and Pharmacokinetic Profile of Vinylidene Chloride in Rats following Oral Administration \| Author: Mckenna M.J. et al. \| Year: 1978 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: The Pharmacokinetics of [14C] Vinylidene Chloride in Rats Following Inhalation Exposure \| Author: McKenna M.J. et al. \| Year: 1978 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes \| Author: Simmonds A.C. et al. \| Year: 2004 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Differential metabolism of 1,1-dichloroethylene in livers of A/J CD-1 and C57BL/6 mice \| Author: Forkert Poh-Gek and Boyd S.M. \| Year: 2001 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Differences in metabolism of vinylidene chloride between mice and rats \| Author: Jones B.K. and Hathway D.E. \| Year: 1977 \| Guideline: 417 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Cytochrome P-450-Dependent Bioactivation of 1,1-dichloroethylene to a Reactive Epoxide in Human Lung and Liver Microsomes \| Author: Dowsley T.F. et al. \| Year: 1998 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Physiologically Based Pharmacokinetic Model for Vinylidene Chloride \| Author: D'Souza R.W. Andersen M.E. \| Year: 1988 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Dermal absorption	*Robust Study Summary* -- Title: In vitro dermal absorption rate testing of certain chemicals of interest to the Occupational Safety and Health Administration: Summary and evaluation of USEPA's mandated testing \| Author: Fasano W.J. and McDougal J.N. \| Year: 2008 \| Guideline: 428 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: A chronic toxicity and oncogenicity study in rats and subchronic toxicity study in dogs on ingested vinylidene chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: 11-DICHLOROETHENE (VINYLIDENE CHLORIDE) \| Author: Benson B \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 453 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 408 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: A chronic toxicity and oncogenicity study in rats and subchronic toxicity study in dogs on ingested vinylidene chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Guideline: 409 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Inhalation Toxicity of Vinyl Chloride and Vinylidene Chloride \| Author: Lee C.C. et al. \| Year: 1977 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Right to refer to study* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Effects on experimental animals of long-term inhalation of trichloroethylene, carbon tetrachloride, 1,1,1-trichloroethane, dichlorodifluoromethane, and 1,1-dichloroethylene \| Author: Prendergast J.A. et al. \| Year: 1967 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 412 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 412 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Range finding and maximul tolerated dose (MTD) study with 1,1-dichloroethylene after a 3-day nose-only inhalation procedure in wistar rats. \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: inhalation	*Right to refer to study* -- Title: Range finding and maximul tolerated dose (MTD) study with 1,1-dichloroethylene after a 3-day nose-only inhalation procedure in wistar rats. \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Developmental toxicity/teratogenicity	*Robust Study Summary* -- Title: Embriotoxicity and Fetotoxicity of inhaled or ingested vinylidene chloride in rats and rabbits \| Author: Murray F.J. et al. \| Year: 1979 \| Guideline: 414 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Developmental toxicity/teratogenicity	*Robust Study Summary* -- Title: The developmental toxicity of vinylidene chloride inhaled by rats and mice during gestation \| Author: Short R.D. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Toxicity to reproduction	*Robust Study Summary* -- Title: A three-generation rat reproductive toxicity study of vinylidene chloride in the drinking water \| Author: Nitschke K.D. et al. \| Year: 1983 \| Guideline: 416 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Toxicity to reproduction	*Robust Study Summary* -- Title: NTP. (2015). NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Inhalation Toxicity of Vinyl Chloride and Vinylidene Chloride \| Author: Lee C.C. et al. \| Year: 1977 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Carcinogenicity of Halogenated Olefinic and Aliphatic Hydrocarbons in Mice \| Author: Van Duuren B.L. et al. \| Year: 1979 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: A Chronic Toxicity and Oncogenicity Study in RAts and Subchronic Toxicity Study in Dogs on Ingested Vinylidene Chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1997 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Robust Study Summary* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 424 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Right to refer to study* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 424 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Robust Study Summary* -- Title: The developmental toxicity of vinylidene chloride inhaled by rats and mice during gestation \| Author: Short R.D. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Eco-Tox \| Short-term toxicity to fish	*Robust Study Summary* -- Title: Vinylidene chloride toxicity to fathead minnows in a flow-through system \| Author: Dill A.C. McCarty W.M Bartlett E.A. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Eco-Tox \| Short-term toxicity to fish	*Right to refer to study* -- Title: Vinylidene chloride toxicity to fathead minnows in a flow-through system \| Author: Dill A.C., McCarty W.M., Bartlett E.A. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Eco-Tox \| Short-term toxicity to aquatic invertebrates	*Robust Study Summary* -- Title: 1,1-DICHLOROETHENE - Daphnia sp. Acute Immobilisation Test \| Author: Gancet C. \| Year: 2010 \| Guideline: 202 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Eco-Tox \| Short-term toxicity to aquatic invertebrates	*Right to refer to study* -- Title: 1,1-DICHLOROETHENE - Daphnia sp. Acute Immobilisation Test \| Author: Gancet C. \| Year: 2010 \| Guideline: 202 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Eco-Tox \| Toxicity to aquatic algae and cyanobacteria	*Robust Study Summary* -- Title: Toxicity Testing of Highly Volatile Chemicals with Green Algae \| Author: Brack W. and Rottler H. \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Eco-Tox \| Toxicity to microorganisms	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Bioaccumulation: aquatic/sediment	*Robust Study Summary* -- Title: Bioconcentration Study of 11-Dichloroethene (Test Substance No. K-876) in Carp \| Author: NITE National Institute of Technology and Evaluation \| Year: 1991 \| Guideline: 305 C \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: Y.	-
Environmental \| Hydrolysis	*Robust Study Summary* -- Title: Homogeneous Hydrolysis Rate Constant for Selected Chlorinated Methanes Ethanes Ethenes and Propanes \| Author: Jeffers P.M. et al. \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradation Study of 1,1-dichloroethylene (Test Substance No. K-876) in Microorganisms [Original title in Japanese] \| Author: NITE National Institute of Technology and Evaluation \| Year: 1989 \| Guideline: 301D \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradability studies with organic priority pollutant compounds. \| Author: Tabak H. et al. \| Year: 1981 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradation of chlorinated ethenes by a methane-utilizing mixed culture. \| Author: Fogel & al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Estimation Programs Interface Suite™ for Microsoft® Windows v 4.1: BIOWIN v4.10 \| Author: US EPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Environmental \| Adsorption/desorption	*Robust Study Summary* -- Title: QSAR: Adsorption-desorption LogKoc - KOCWIN v.2.0 \| Author: USEPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Environmental \| Adsorption/desorption	*Robust Study Summary* -- Title: QSAR: Adsorption-desorption LogKoc- KOCWIN v.2.0 \| Author: USEPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Environmental \| Biodegradation in water and sediment: simulation tests	*Robust Study Summary* -- Title: Biotransformation of Select Alkylbenzenes and Halogenated Aliphatic Hydrocabons in Methanogenic Aquifer Material: A Microcosm Study \| Author: Wilson B.H. et al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Distribution modelling	*Robust Study Summary* -- Title: EQC Model: Fugacity-Based EQC-Equilibrium Criterion Model (Version 2.02 - May 2003) \| Author: The Canadian Centre for Environmental Modelling and Chemistry \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: AOPWIN v1.92a \| Author: AOPWIN \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Atmospheric Chemistry of Several Toxic Compounds \| Author: Edward Edney, Steven Mitchell and Joseph Bufalini \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Atmospheric chemistry of toxic contaminants. 5. Unsaturated halogenated aliphatics: allyl chloride chloroprene hexachlorocyclopentadiene Vinylidene chloride \| Author: Grosjean D. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Monitoring data	*Robust Study Summary* -- Title: State-of-the-art of gas chromatography-based methods for analysis of anthropogenic volatile organic compounds in estuarine waters illustrated with the river Scheldt as an example. \| Author: Huybrechts T., Dewulf J., and Van Langenhove H. \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Monitoring data	*Robust Study Summary* -- Title: Organic trace compounds in the water of the River Elbe near Hamburg. Part I. \| Author: Götz R. et al. \| Year: 1998 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-

Study name	Short Description	Data Owner
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Budavari S \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Budavari S \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: No information \| Author: Lewis R.J. Sr (Ed.) \| Year: 1997 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Appearance/physical state/colour	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Melting point/freezing point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Boiling point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: 9798 Vinylidene Chloride \| Author: Windholz (Ed) \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Density	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Vapour pressure	*Robust Study Summary* -- Title: Physical constants of organic compounds \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: No information \| Author: ECHA \| Year: 2012 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: HENRYWIN v3.20 \| Author: HENRYWIN \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: Interphase transfer processes. II. Evaporation rates of Chloro Methanes Ethanes Ethylenes Propanes and Propylenes from dilute aqueous solutions. Comparaison with theorical predctions. \| Author: Dilling W.L. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Henry's law constant	*Robust Study Summary* -- Title: WVOLNT.EXE \| Author: WVOLNT \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Solubilities of Vinyl Chloride and Vinylidene Chloride in Water \| Author: DeLassus P. and Schmidt D.D. \| Year: 1981 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Water solubility	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Partition coefficient	*Robust Study Summary* -- Title: Octanol-water Partition coefficients \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Viscosity of Liquid \| Author: Yaws Carl L. \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Viscosity	*Robust Study Summary* -- Title: Table 5.16 Viscosity and Surface Tension of Various Organic Substances \| Author: Dean J.A. \| Year: 1999 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Solubility in organic solvents/fat solubility	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Solubility in organic solvents/fat solubility	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Flammability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flammability	*Robust Study Summary* -- Title: vinylidene chloride \| Author: Lewis Richard J. Sr. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Flammability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Chapter 38, Halogenated Aliphatic Hydrocarbons containing Chlorine, Bromine, and Iodine \| Author: T.R. Torkelson \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Flash point	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Flamability of chemical substances \| Author: Lide D.R. (ed.) \| Year: 2000 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Vinylidene chloride polymers \| Author: R. A. Wessling et al. \| Year: 2002 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Phys-Chem \| Auto-ignition temperature	*Robust Study Summary* -- Title: Chlorinated Hydrocarbons \| Author: Manfred Rossberg et al. \| Year: 2006 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Skin irritation / corrosion	*Robust Study Summary* -- Title: IN VITRO SKIN CORROSION: HUMAN SKIN MODEL TEST WITH 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Right to refer to study* -- Title: IN VITRO SKIN CORROSION: HUMAN SKIN MODEL TEST WITH 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Robust Study Summary* -- Title: In vitro skin irritation test:human skin model test with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin irritation / corrosion	*Right to refer to study* -- Title: In vitro skin irritation test:human skin model test with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Eye irritation	*Robust Study Summary* -- Title: Bovine Corneal Opacity and Permeability Assay (BCOP) with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Eye irritation	*Right to refer to study* -- Title: Bovine Corneal Opacity and Permeability Assay (BCOP) with 1,1-dichloroethylene \| Author: Andreas Heppenheimer \| Year: 2010 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Skin sensitisation	*Robust Study Summary* -- Title: Preliminary assessment of the skin sensitizing activity of selected rodent carcinogens using the local lymph node assay \| Author: Warbrick E.V. et al. \| Year: 2001 \| Guideline: 429 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Tissue-mediated mutagenicity of vinylidene chloride and 2-chlorobutadiene in Salmonella typhimurium \| Author: Bartsch H. et al. \| Year: 1975 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Validation and comparative studies on 180 chemicals with S. thyphimurium strains and V79 chinese hamster cells in the presence of various metabolizing systems \| Author: Bartsch H. et al. \| Year: 1980 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in mammalian cells	*Robust Study Summary* -- Title: Responses of the L5178Y Mouse Lymphoma Forward Mutation Assay: V. Gases and Vapors \| Author: Mc Gregor D. et al. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in mammalian cells	*Robust Study Summary* -- Title: Validation and comparative studies on 180 chemicals with S. thyphimurium strains and V79 chinese hamster cells in the presence of various metabolizing systems \| Author: Bartsch H. et al. \| Year: 1980 \| Guideline: 476 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: An association between mutagenicity of the Ara test of Salmonella typhimurium and carcinogenicity in rodents for 16 halogenated aliphatic hydrocarbons \| Author: Roldan-Arjona T. et al. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation \| Author: Greim H. et al. \| Year: 1975 \| Guideline: 471 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: Genetic effects of chlorinated ethylenes in the yeast Saccharomyces cerevisiae \| Author: Koch R., Schlegelmich R. and Wolf H.U. \| Year: 1988 \| Guideline: 481 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro gene mutation study in bacteria (Ames)	*Robust Study Summary* -- Title: The induction of mitotic chromosome malsegregation in Aspergillus nidulans. Quantitative structure activity relationship (QSAR) analysis with chlorinated aliphatic hydrocarbons \| Author: Crebelli R. et al. \| Year: 1992 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro cytogenicity study in mammalian cells (CA)	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 473 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| in vitro cytogenicity study in mammalian cells (CA)	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 479 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Cytogenetic studies on 1,1-dichloroethylene and its two isomers in mammalian cells in vitro and in vivo \| Author: Sawada M., Sofuni T. and Ishidate Jr. M. \| Year: 1987 \| Guideline: 474 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2013 \| Guideline: 474 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: A dominant lethal study in male rats after repeated exposures to vinyl chloride or vinylidene chloride \| Author: Short R.D. et al. \| Year: 1977 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Current status of bioassays in genetic toxicology - the dominant lethal assay \| Author: Green S. et al. \| Year: 1985 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Dominant Lethal Studies with the Halogenated Olefins Vinyl Chloride and Vinylidene Dichloride in Male CD-1 Mice \| Author: Anderson D, Hodge M.C.E., and Purchase I.F.H. \| Year: 1977 \| Guideline: 478 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Chemical Mutagenesis Testing in Drosophila. IX. Results of 50 Coded Compounds Tested for the National Toxicology Program \| Author: Foureman P. et al. \| Year: 1994 \| Guideline: 477 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: Effects of Vinylidene Chloride on DNA Synthesis and DNA Repair in the Rat and Mouse: A Comparative Study with Dimethylnitrosamine \| Author: Reitz R.H. et al. \| Year: 1980 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2013 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Genetic toxicity in vivo	*Robust Study Summary* -- Title: The alkaline in vivo comet assay with 1,1-dichloroethylene in lung liver kidney and bone marrow of Wistar Han rats after nose only inhalation exposure \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Genetic toxicity in vivo	*Right to refer to study* -- Title: The alkaline in vivo comet assay with 1,1-dichloroethylene in lung liver kidney and bone marrow of Wistar Han rats after nose only inhalation exposure \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Toxicological \| Acute toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid als Dampf bei 4-Stündiger Exposition an Sprague-Dawley Ratten (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylchlorid bei 4 stüdiger Exposition an NMRI-Mäusen (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylchlorid bei 4 stüdiger Exposition an NMRI-Mäusen (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4 stündiger Exposition an chinesischen Streifenhamstern (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4 stündiger Exposition an chinesischen Streifenhamstern (nüchtern) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Robust Study Summary* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4stündiger Exposition an chinesischen Streifenhamstern (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Acute toxicity: inhalation	*Right to refer to study* -- Title: Bericht über die Bestimmung der akuten Inhalationstoxizität LC50 von Vinylidenchlorid bei 4-stündiger Exposition an chinesischen Streifenhamstern (gefüttert) \| Author: Zeller H. and Klimish H.J. \| Year: 1979 \| Guideline: 403 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: The biological fate of vinylidene chloride in rats \| Author: Jones B.K. and Hathway D.E. \| Year: 1978 \| Guideline: 417 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene \| Author: Dowsley T.F. et al. \| Year: 1995 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Metabolism and Pharmacokinetic Profile of Vinylidene Chloride in Rats following Oral Administration \| Author: Mckenna M.J. et al. \| Year: 1978 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: The Pharmacokinetics of [14C] Vinylidene Chloride in Rats Following Inhalation Exposure \| Author: McKenna M.J. et al. \| Year: 1978 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Bioactivation of 1,1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes \| Author: Simmonds A.C. et al. \| Year: 2004 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Differential metabolism of 1,1-dichloroethylene in livers of A/J CD-1 and C57BL/6 mice \| Author: Forkert Poh-Gek and Boyd S.M. \| Year: 2001 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Differences in metabolism of vinylidene chloride between mice and rats \| Author: Jones B.K. and Hathway D.E. \| Year: 1977 \| Guideline: 417 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Cytochrome P-450-Dependent Bioactivation of 1,1-dichloroethylene to a Reactive Epoxide in Human Lung and Liver Microsomes \| Author: Dowsley T.F. et al. \| Year: 1998 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Basic toxicokinetics	*Robust Study Summary* -- Title: Physiologically Based Pharmacokinetic Model for Vinylidene Chloride \| Author: D'Souza R.W. Andersen M.E. \| Year: 1988 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Dermal absorption	*Robust Study Summary* -- Title: In vitro dermal absorption rate testing of certain chemicals of interest to the Occupational Safety and Health Administration: Summary and evaluation of USEPA's mandated testing \| Author: Fasano W.J. and McDougal J.N. \| Year: 2008 \| Guideline: 428 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: A chronic toxicity and oncogenicity study in rats and subchronic toxicity study in dogs on ingested vinylidene chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: 11-DICHLOROETHENE (VINYLIDENE CHLORIDE) \| Author: Benson B \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 453 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 408 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: oral	*Robust Study Summary* -- Title: A chronic toxicity and oncogenicity study in rats and subchronic toxicity study in dogs on ingested vinylidene chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Guideline: 409 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Inhalation Toxicity of Vinyl Chloride and Vinylidene Chloride \| Author: Lee C.C. et al. \| Year: 1977 \| Guideline: 452 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Right to refer to study* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Effects on experimental animals of long-term inhalation of trichloroethylene, carbon tetrachloride, 1,1,1-trichloroethane, dichlorodifluoromethane, and 1,1-dichloroethylene \| Author: Prendergast J.A. et al. \| Year: 1967 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 412 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 413 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Guideline: 412 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: Y.	-
Toxicological \| Repeated dose toxicity: inhalation	*Robust Study Summary* -- Title: Range finding and maximul tolerated dose (MTD) study with 1,1-dichloroethylene after a 3-day nose-only inhalation procedure in wistar rats. \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Repeated dose toxicity: inhalation	*Right to refer to study* -- Title: Range finding and maximul tolerated dose (MTD) study with 1,1-dichloroethylene after a 3-day nose-only inhalation procedure in wistar rats. \| Author: van Huygevoort A.H.B.M. \| Year: 2016 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: supporting study \| GLP: N.	-
Toxicological \| Developmental toxicity/teratogenicity	*Robust Study Summary* -- Title: Embriotoxicity and Fetotoxicity of inhaled or ingested vinylidene chloride in rats and rabbits \| Author: Murray F.J. et al. \| Year: 1979 \| Guideline: 414 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Toxicological \| Developmental toxicity/teratogenicity	*Robust Study Summary* -- Title: The developmental toxicity of vinylidene chloride inhaled by rats and mice during gestation \| Author: Short R.D. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Toxicological \| Toxicity to reproduction	*Robust Study Summary* -- Title: A three-generation rat reproductive toxicity study of vinylidene chloride in the drinking water \| Author: Nitschke K.D. et al. \| Year: 1983 \| Guideline: 416 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Toxicity to reproduction	*Robust Study Summary* -- Title: NTP. (2015). NTP technical report on the toxicology and carcinogenesis of vinylidene chloride (CAS No. 75-35-4) in F344/N rats and B6C3F1/N mice (inhalation studies) DRAFT REPORT \| Author: NTP \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Inhalation Toxicity of Vinyl Chloride and Vinylidene Chloride \| Author: Lee C.C. et al. \| Year: 1977 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Carcinogenicity of Halogenated Olefinic and Aliphatic Hydrocarbons in Mice \| Author: Van Duuren B.L. et al. \| Year: 1979 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Carcinogenesis bioassay of Vinylidene chloride (CAS NO. 75-35-4) in F344 rats and B6C3F1 mice (gavage study) \| Author: National Toxicology Program \| Year: 1982 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: A Chronic Toxicity and Oncogenicity Study in RAts and Subchronic Toxicity Study in Dogs on Ingested Vinylidene Chloride \| Author: Quast J.F. et al. \| Year: 1983 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1997 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Chronic toxicity and oncogenicity study on inhaled vinylidene chloride in rats \| Author: Quast J.F. et al. \| Year: 1986 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Interim Results of Two-Year Toxicological Studies in Rats of Vinylidene Chloride Incorporated in the Drinking Water or Administered by Repeated Inhalation \| Author: Rampy L. W. et al. \| Year: 1977 \| Guideline: 451 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Carcinogenicity	*Robust Study Summary* -- Title: Toxicology and carcinogenesis studies of vinylidene chloride (CAS NO. 75-35-4) IN F344/N rats and B6C3F1/N mice (inhalation studies) \| Author: National Toxicology Program \| Year: 2015 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Robust Study Summary* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 424 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Right to refer to study* -- Title: Repeated (90-day) inhalation neurotoxicity study with Vinylidene Chloride in rats \| Author: Dr D.M.G. de Groot and Dr J.C.H.M. Lammers \| Year: 2004 \| Guideline: 424 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: Y.	-
Toxicological \| Neurotoxicity	*Robust Study Summary* -- Title: The developmental toxicity of vinylidene chloride inhaled by rats and mice during gestation \| Author: Short R.D. et al. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Eco-Tox \| Short-term toxicity to fish	*Robust Study Summary* -- Title: Vinylidene chloride toxicity to fathead minnows in a flow-through system \| Author: Dill A.C. McCarty W.M Bartlett E.A. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Eco-Tox \| Short-term toxicity to fish	*Right to refer to study* -- Title: Vinylidene chloride toxicity to fathead minnows in a flow-through system \| Author: Dill A.C., McCarty W.M., Bartlett E.A. \| Year: 1977 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: N.	-
Eco-Tox \| Short-term toxicity to aquatic invertebrates	*Robust Study Summary* -- Title: 1,1-DICHLOROETHENE - Daphnia sp. Acute Immobilisation Test \| Author: Gancet C. \| Year: 2010 \| Guideline: 202 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Eco-Tox \| Short-term toxicity to aquatic invertebrates	*Right to refer to study* -- Title: 1,1-DICHLOROETHENE - Daphnia sp. Acute Immobilisation Test \| Author: Gancet C. \| Year: 2010 \| Guideline: 202 \| Klimisch score: 1 - Reliable without restriction \| Adequacy: key study \| GLP: Y.	-
Eco-Tox \| Toxicity to aquatic algae and cyanobacteria	*Robust Study Summary* -- Title: Toxicity Testing of Highly Volatile Chemicals with Green Algae \| Author: Brack W. and Rottler H. \| Year: 1994 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Eco-Tox \| Toxicity to microorganisms	*Robust Study Summary* -- Title: 1,1-dichloroethylene \| Author: Verschueren K. \| Year: 1996 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Bioaccumulation: aquatic/sediment	*Robust Study Summary* -- Title: Bioconcentration Study of 11-Dichloroethene (Test Substance No. K-876) in Carp \| Author: NITE National Institute of Technology and Evaluation \| Year: 1991 \| Guideline: 305 C \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study \| GLP: Y.	-
Environmental \| Hydrolysis	*Robust Study Summary* -- Title: Homogeneous Hydrolysis Rate Constant for Selected Chlorinated Methanes Ethanes Ethenes and Propanes \| Author: Jeffers P.M. et al. \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradation Study of 1,1-dichloroethylene (Test Substance No. K-876) in Microorganisms [Original title in Japanese] \| Author: NITE National Institute of Technology and Evaluation \| Year: 1989 \| Guideline: 301D \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradability studies with organic priority pollutant compounds. \| Author: Tabak H. et al. \| Year: 1981 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Biodegradation of chlorinated ethenes by a methane-utilizing mixed culture. \| Author: Fogel & al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Biodegradation in water: screening tests	*Robust Study Summary* -- Title: Estimation Programs Interface Suite™ for Microsoft® Windows v 4.1: BIOWIN v4.10 \| Author: US EPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence \| GLP: N.	-
Environmental \| Adsorption/desorption	*Robust Study Summary* -- Title: QSAR: Adsorption-desorption LogKoc - KOCWIN v.2.0 \| Author: USEPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Environmental \| Adsorption/desorption	*Robust Study Summary* -- Title: QSAR: Adsorption-desorption LogKoc- KOCWIN v.2.0 \| Author: USEPA \| Year: 2010 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study \| GLP: N.	-
Environmental \| Biodegradation in water and sediment: simulation tests	*Robust Study Summary* -- Title: Biotransformation of Select Alkylbenzenes and Halogenated Aliphatic Hydrocabons in Methanogenic Aquifer Material: A Microcosm Study \| Author: Wilson B.H. et al. \| Year: 1986 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Distribution modelling	*Robust Study Summary* -- Title: EQC Model: Fugacity-Based EQC-Equilibrium Criterion Model (Version 2.02 - May 2003) \| Author: The Canadian Centre for Environmental Modelling and Chemistry \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: key study.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: AOPWIN v1.92a \| Author: AOPWIN \| Year: 2008 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Atmospheric Chemistry of Several Toxic Compounds \| Author: Edward Edney, Steven Mitchell and Joseph Bufalini \| Year: 1983 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Vinylidene Chloride \| Author: P.H. Howard (Ed.) \| Year: 1989 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Phototransformation in air	*Robust Study Summary* -- Title: Atmospheric chemistry of toxic contaminants. 5. Unsaturated halogenated aliphatics: allyl chloride chloroprene hexachlorocyclopentadiene Vinylidene chloride \| Author: Grosjean D. \| Year: 1991 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: weight of evidence.	-
Environmental \| Monitoring data	*Robust Study Summary* -- Title: State-of-the-art of gas chromatography-based methods for analysis of anthropogenic volatile organic compounds in estuarine waters illustrated with the river Scheldt as an example. \| Author: Huybrechts T., Dewulf J., and Van Langenhove H. \| Year: 2003 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-
Environmental \| Monitoring data	*Robust Study Summary* -- Title: Organic trace compounds in the water of the River Elbe near Hamburg. Part I. \| Author: Götz R. et al. \| Year: 1998 \| Klimisch score: 2 - Reliable with restrictions \| Adequacy: supporting study.	-

CAS 75-35-4 | Data Package > 1000 t/a

Includes: