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| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | Carcinogenicity | Right to refer to study -- Title: Toxicology and carcinogenesis studies of dichloromethane (methylene chloride) (CAS No. 75-09-2) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of dichloromethane (methylene chloride) (CAS No. 75-09-2) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Carcinogenicity | Right to refer to study -- Title: Toxicology and carcinogenesis studies of dichloromethane (methylene chloride) (CAS No. 75-09-2) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Carcinogenicity | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of dichloromethane (methylene chloride) (CAS No. 75-09-2) in F344/N rats and B6C3F1 mice (inhalation studies) | Author: NTP | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Right to refer to study -- Title: Introductory study of the biodegradation of the chlorinated methane, ethane, and ethene compounds. Progress Report | Author: Wood PR et al. | Year: 1980 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Biodegradation in water and sediment: simulation tests | Robust Study Summary -- Title: Introductory study of the biodegradation of the chlorinated methane, ethane, and ethene compounds. Progress Report | Author: Wood PR et al. | Year: 1980 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Biodegradation in soil | Right to refer to study -- Title: The biodegradation of methylene chloride in soils | Author: Davis JW, Madsen SS | Year: 1991 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: The biodegradation of methylene chloride in soils | Author: Davis JW, Madsen SS | Year: 1991 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Bioaccumulation: aquatic / sediment | Right to refer to study -- Title: Bio-accumulation study on dichloromethane | Author: Chemicals Inspection and Testing Institute, Japan | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Bioaccumulation: aquatic / sediment | Robust Study Summary -- Title: Bio-accumulation study on dichloromethane | Author: Chemicals Inspection and Testing Institute, Japan | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Distribution modelling | Right to refer to study -- Title: EPISUITE Level III fugacity model, US Environmental Protection Agency | Author: USEPA | Year: 2008 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Distribution modelling | Robust Study Summary -- Title: EPISUITE Level III fugacity model, US Environmental Protection Agency | Author: USEPA | Year: 2008 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: A two-year drinking-water study of dichloromethane in rodents I. Rats | Author: Serota DG et al. | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: A two-year drinking-water study of dichloromethane in rodents I. Rats | Author: Serota DG et al. | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Methylene chloride: A 2-year inhalation toxicity and oncogenicity study in rats. | Author: Nitschke KD et al. | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Methylene chloride: A 2-year inhalation toxicity and oncogenicity study in rats. | Author: Nitschke KD et al. | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Developmental toxicity / teratogenicity | Right to refer to study -- Title: Absence of dichloromethane teratogenicity with inhalation exposure in rats | Author: Hardin BD, Manson JM | Year: 1980 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Developmental toxicity / teratogenicity | Robust Study Summary -- Title: Absence of dichloromethane teratogenicity with inhalation exposure in rats | Author: Hardin BD, Manson JM | Year: 1980 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Developmental toxicity / teratogenicity | Right to refer to study -- Title: The effect of maternally inhaled trichloroethylene, perchloroethylene, methylene chloroform, methylene chloride on embryonal and fetal development in mice and rats | Author: Dow Chemical Company | Year: 1974 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Developmental toxicity / teratogenicity | Robust Study Summary -- Title: The effect of maternally inhaled trichloroethylene, perchloroethylene, methylene chloroform, methylene chloride on embryonal and fetal development in mice and rats | Author: Dow Chemical Company | Year: 1974 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: CRC Handbook of chemistry and physics | Author: Lide DR | Year: 1994 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of chemistry and physics | Author: Lide DR | Year: 1994 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: CRC handbook of chemistry and physics | Author: Lide DR | Year: 1994 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC handbook of chemistry and physics | Author: Lide DR | Year: 1994 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Density | Right to refer to study -- Author: Weast RC, Astle MJ, Beyer WH | Year: 1988 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Density | Robust Study Summary -- Author: Weast RC, Astle MJ, Beyer WH | Year: 1988 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Estimation of log Kow for dichloromethane (CAS 75-09-2 ) using EPISUITE 4.0 | Author: Zvinavashe E | Year: 2012 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation of log Kow for dichloromethane (CAS 75-09-2 ) using EPISUITE 4.0 | Author: Zvinavashe E | Year: 2012 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Illustrated Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals | Author: Mackay D, Shiu WY, Ma KC | Year: 1993 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradability of dichloromethane (CAS 75-09-2) in the closed bottle test (OECD TG 301D) | Author: Ginkel van CG | Year: 2012 | Guideline: 301D | Klimisch score: 1 (reliable without restriction) | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradability of dichloromethane (CAS 75-09-2) in the closed bottle test (OECD TG 301D) | Author: Ginkel van CG | Year: 2012 | Guideline: 301D | Klimisch score: 1 (reliable without restriction). | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Toxicity of perchloroethane, and methylene chloride to fathead minnows | Author: Alexander HC, McCarty WM, Bartlett EA | Year: 1978 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Toxicity of perchloroethane, and methylene chloride to fathead minnows | Author: Alexander HC, McCarty WM, Bartlett EA | Year: 1978 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Toxicity of methylene chloride to daphnids | Author: McCarty WM | Year: 1979 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Toxicity of methylene chloride to daphnids | Author: McCarty WM | Year: 1979 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute Toxicity of Cadmium, Copper, Zinc, Ammonia, 3,3'Dichlorobenzidine, 2,6-Dichloro-4-Nitroaniline, Methylene Chloride and 2,4,6- Trichlorophenol to Juvenile Grass Shrimp and Kilifish | Author: Burton DT, Fisher DJ | Year: 1990 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Toxicity of Cadmium, Copper, Zinc, Ammonia, 3,3'Dichlorobenzidine, 2,6-Dichloro-4-Nitroaniline, Methylene Chloride and 2,4,6- Trichlorophenol to Juvenile Grass Shrimp and Kilifish | Author: Burton DT, Fisher DJ | Year: 1990 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity study with dichloromethane in rats. | Author: Janssen PJM, Pot TE | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity study with dichloromethane in rats. | Author: Janssen PJM, Pot TE | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane, trichloroethylene, tetrachloroethylene and 1,1,1-trichloroethane | Author: Beek van L | Year: 1990 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Investigation of a possibility to reduce the use of rabbits in skin irritation tests; experiments with dichloromethane, trichloroethylene, tetrachloroethylene and 1,1,1-trichloroethane | Author: Beek van L | Year: 1990 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Assessment of contact hypersensitivity to Dichloromethane in the mouse (Local Lymph Node Assay) | Author: Huygevoort AHBM | Year: 2010 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of contact hypersensitivity to Dichloromethane in the mouse (Local Lymph Node Assay) | Author: Huygevoort AHBM | Year: 2010 | Klimisch score: 1 (reliable without restriction) | - |
| Phys-Chem | Flash point | Right to refer to study -- Author: Nabert K, Schön G | Year: 1963 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Flash point | Robust Study Summary -- Author: Nabert K, Schön G | Year: 1963 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Auto flammability | Right to refer to study -- Author: Nabert K, Schön G | Year: 1963 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Auto flammability | Robust Study Summary -- Author: Nabert K, Schön G | Year: 1963 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Evaporation rates of methyl chloride, chloroform, 1,1,1-trichloroethane, trichloroethylene, tetrachloroethylene, and other chlorinated compounds in dilute aqueous solutions | Author: Dilling WL, Tefertiller NB, & Kallos GJ | Year: 1975 | Klimisch score: 2 (reliable with restrictions) | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Evaporation rates of methyl chloride, chloroform, 1,1,1-trichloroethane, trichloroethylene, tetrachloroethylene, and other chlorinated compounds in dilute aqueous solutions | Author: Dilling WL, Tefertiller NB, & Kallos GJ | Year: 1975 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: The toxicity and narcotic action of mono-chloromono- bromo-methane with special reference to inorganic and volatile bromide in blood, urine and brain. | Author: Svirbely JL, Highman B, Alford WF, et al. | Year: 1947 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: The toxicity and narcotic action of mono-chloromono- bromo-methane with special reference to inorganic and volatile bromide in blood, urine and brain. | Author: Svirbely JL, Highman B, Alford WF, et al. | Year: 1947 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Acute dermal toxicity study with dichloromethane in rats | Author: Janssen PJM, Pot TE | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Acute dermal toxicity study with dichloromethane in rats | Author: Janssen PJM, Pot TE | Year: 1988 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Ophthalmic toxicology of dichloromethane | Author: Ballantyne B, Gazzard MF, Swanson DW | Year: 1976 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Ophthalmic toxicology of dichloromethane | Author: Ballantyne B, Gazzard MF, Swanson DW | Year: 1976 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Genetic toxicity in vitro | Right to refer to study -- Title: Induction of chromosome damage by methylene chloride in CHO cells | Author: Thilagar AK, Kumaroo PV | Year: 1983 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Genetic toxicity in vitro | Robust Study Summary -- Title: Induction of chromosome damage by methylene chloride in CHO cells | Author: Thilagar AK, Kumaroo PV | Year: 1983 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Methylene Chloride: Two generation inhalation reproduction study in fischer 344 rats | Author: Dow Chemical Company | Year: 1985 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Methylene Chloride: Two generation inhalation reproduction study in fischer 344 rats | Author: Dow Chemical Company | Year: 1985 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Genetic toxicity in vitro | Right to refer to study -- Title: Mutagenicity of cosmetic ingredients licensed by the European Communities | Author: Gocke E, King M-T, Eckhardt K, Wild D | Year: 1981 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Genetic toxicity in vitro | Robust Study Summary -- Title: Mutagenicity of cosmetic ingredients licensed by the European Communities | Author: Gocke E, King M-T, Eckhardt K, Wild D | Year: 1981 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Excess molar volumes and excess viscosities of 2-propanol + methylacetate + dichloromethane at 298.15 K | Author: Acevedo IL, Postigo MA, Katz M | Year: 1988 | Klimisch score: 2 (reliable with restrictions) | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Excess molar volumes and excess viscosities of 2-propanol + methylacetate + dichloromethane at 298.15 K | Author: Acevedo IL, Postigo MA, Katz M | Year: 1988 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Long-term toxicity to fish | Right to refer to study -- Title: Toxicity of Methylene Chloride to Life Stages of the Fathead Minnow | Author: Dill DC, Murphy PG, Mayes MA | Year: 1987 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Toxicity of Methylene Chloride to Life Stages of the Fathead Minnow | Author: Dill DC, Murphy PG, Mayes MA | Year: 1987 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Toxicity assessment of common xenobiotic compounds on municipal activated sludge: comparison between respirometry and Microtoxs | Author: Ricco G, Tomei MC, Ramadori R, Laer R | Year: 2004 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Toxicity assessment of common xenobiotic compounds on municipal activated sludge: comparison between respirometry and Microtoxs | Author: Ricco G, Tomei MC, Ramadori R, Laer R | Year: 2004 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Toxicity to soil microorganisms | Right to refer to study -- Title: Effect of trichloroethylene, tetrachloroethylene and dichloromethane on enzymatic activities in soil. | Author: Kanazawa S, Filip Z | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Eco-Tox | Toxicity to soil microorganisms | Robust Study Summary -- Title: Effect of trichloroethylene, tetrachloroethylene and dichloromethane on enzymatic activities in soil. | Author: Kanazawa S, Filip Z | Year: 1986 | Klimisch score: 2 (reliable with restrictions) | - |
| Toxicological | Genetic toxicity in vivo | Right to refer to study -- Title: Methylene chloride (dichloromethane): An evaluation in the mouse micronucleus test | Author: Sheldon T, Richardson CR, Hamilton K, Randall V, Hart D, Hollis K | Year: 1986 | Klimisch score: 1 (reliable without restriction) | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Methylene chloride (dichloromethane): An evaluation in the mouse micronucleus test | Author: Sheldon T, Richardson CR, Hamilton K, Randall V, Hart D, Hollis K | Year: 1986 | Klimisch score: 1 (reliable without restriction) | - |