You are here: Home> South Korea>K-REACH>CAS 681-84-5> CAS 681-84-5 | Data Package 1 - 10 t/a
| Study name | Short Description | Data Owner |
|---|---|---|
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1). | Author: Hüls AG | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Determination of the acute effects of DYNASIL A On fish (in accordance with EG 92/69 C 1). | Author: Hüls AG | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Ethyl Silicate -Acute Toxicity to Water Fleas, (Daphnia magna) Under Flow-Through Conditions. | Author: Springborn Smithers Laboratories | Year: 2006 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Ethyl Silicate -Acute Toxicity to Water Fleas, (Daphnia magna) Under Flow-Through Conditions. | Author: Springborn Smithers Laboratories | Year: 2006 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CorrectionTest Report No. A110011975 according to DIN EN ISO/IEC 17025 | Author: AQura GmbH | Year: 2011 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: CorrectionTest Report No. A110011975 according to DIN EN ISO/IEC 17025 | Author: AQura GmbH | Year: 2011 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Test for skin sensitization by DYNASIL A In guinea pigs. | Author: Degussa-Huls AG | Year: 1993 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Test for skin sensitization by DYNASIL A In guinea pigs. | Author: Degussa-Huls AG | Year: 1993 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Determination of the Flash Point of Tetramethyl orthosilicate | Author: AQura GmbH | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Determination of the Flash Point of Tetramethyl orthosilicate | Author: AQura GmbH | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute dermal irritation in the rabbit | Author: SafePharm Laboratories Ltd | Year: 2001 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute dermal irritation in the rabbit | Author: SafePharm Laboratories Ltd | Year: 2001 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Waiver | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide, D. R. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: DETERMINATION OF THE VAPOUR PRESSURE OF TETRAMETHYL ORTHOSILICATE | Author: NOTOX B.V. | Year: 2012 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: DETERMINATION OF THE VAPOUR PRESSURE OF TETRAMETHYL ORTHOSILICATE | Author: NOTOX B.V. | Year: 2012 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Waiver | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity in the rat acute toxic class method | Author: SafePharm laboratories | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity in the rat acute toxic class method | Author: SafePharm laboratories | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: KBM-04: Reverse mutation assay 'Ames Test' using Salmonella typhimurium and Escherichia coli | Author: Safepharm | Year: 2001 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: KBM-04: Reverse mutation assay 'Ames Test' using Salmonella typhimurium and Escherichia coli | Author: Safepharm | Year: 2001 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics | Author: Lide, D. R. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Waiver | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazleton Laboratories | Year: 1966 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazleton Laboratories | Year: 1966 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazleton Laboratories | Year: 1966 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Acute Oral Administration - Rats, Primary Skin Irritation - Rabbits; Acute Eye Irritation - Rabbits - Methyltrimethoxysilane, Triethoxysilane, Trimethoxysilane, Tetramethoxysilane | Author: Hazleton Laboratories | Year: 1966 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the water solubility of tetramethyl orthosilicate | Author: Vitis Regulatory | Year: 2025 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the water solubility of tetramethyl orthosilicate | Author: Vitis Regulatory | Year: 2025 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of WaterNT v 1.01 (EPI Suite) for the calculation of the water solubility of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Chemistry and Physics | Author: Weast, R. C. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow of tetramethyl orthosilicate | Author: Vitis Regulatory | Year: 2025 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Prediction Reporting Format (QPRF) for the log Kow of tetramethyl orthosilicate | Author: Vitis Regulatory | Year: 2025 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: QSAR Model Reporting Format: Adaptation of KOWWIN v1.67 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (Log Kow) of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: QSAR Model Reporting Format: Adaptation of KOWWIN v1.67 (EPI Suite) for the calculation of the n-octanol-water partition coefficient (Log Kow) of organosilicon compounds Version 3 | Author: Peter Fisk Associates | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Physical Properties Determination of Silanes | Author: Chilworth Technology Inc. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Physical Properties Determination of Silanes | Author: Chilworth Technology Inc. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Determination of the acute effects of DYNASIL A On the swimming behaviour of Daphnia magna (in accordance with EC 84/449, Nov. 1989) | Author: Hüls AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Determination of the acute effects of DYNASIL A On the swimming behaviour of Daphnia magna (in accordance with EC 84/449, Nov. 1989) | Author: Hüls AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Test for skin irritation by DYNASYL A In rabbits. | Author: Degussa-Huls AG | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Test for skin irritation by DYNASYL A In rabbits. | Author: Degussa-Huls AG | Year: 1992 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Safety Data Sheet for Dynasylan M | Author: Evonik | Year: 2007 | Guideline: 103 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Methyl Silicate from Silicon and Methanol | Author: Rochow, E. G. | Year: 1948 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Critcial Point and Vapor Pressure Measurements on Tetramethoxysilane by Means of a Flow Method with Ulta-low Residence Times | Author: Wiltec Research Company | Year: 2003 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Critcial Point and Vapor Pressure Measurements on Tetramethoxysilane by Means of a Flow Method with Ulta-low Residence Times | Author: Wiltec Research Company | Year: 2003 | Klimisch score: 3 - Not reliable | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Safety Data Sheet for Dynasylan M | Author: Evonik | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Safety Data Sheet for Dynasylan M | Author: Evonik | Year: 2007 | Guideline: 109 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Safety Data Sheet for Dynasylan M | Author: Evonik | Year: 2007 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Determination of the biodegradability of DYNASIL A In DOC-DIE AWAY TEST. | Author: Huls Stock Corp., | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Determination of the biodegradability of DYNASIL A In DOC-DIE AWAY TEST. | Author: Huls Stock Corp., | Year: 1993 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Genetic evaluation of Tetramethoxy-silane in bacterial reverse mutation assays | Author: Dow Corning Corporation | Year: 1987 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Genetic evaluation of Tetramethoxy-silane in bacterial reverse mutation assays | Author: Dow Corning Corporation | Year: 1987 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: The 2000-2001 Aldrich Handbook of Fine Chemicals and Laboratory Equipment | Author: Aldrich Chemical Co. | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: The 2000-2001 Aldrich Handbook of Fine Chemicals and Laboratory Equipment | Author: Aldrich Chemical Co. | Year: 2000 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Transport Properties of Liquids. I. Self-Diffusion, Viscosity and Density of Nearly Spherical and Disk Like Molecules in the Pure Liquid Phase | Author: Vogel, H., Weiss, A. | Year: 1981 | Guideline: 102 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Safety Data Sheet for Dynasylan M | Author: Evonik | Year: 2007 | Guideline: 104 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Final Report for Flammability Evaluations of Nine Select Silane, Siloxane, and Silazane Compounds by ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: 103 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Final Report for Flammability Evaluations of Nine Select Silane, Siloxane, and Silazane Compounds by ASTM E 681 | Author: Southwest Research Institute | Year: 2000 | Guideline: 103 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Organosilicon materials | Author: Spivack JL et al | Year: 1997 | Guideline: 103 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: SPLG 396 Acute oral toxicity study in male and female Wistar rats | Author: Bayer AG | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: SPLG 396 Acute oral toxicity study in male and female Wistar rats | Author: Bayer AG | Year: 2001 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |