You are here: Home> Turkey>TR-REACH>CAS 50586-59-9> CAS 50586-59-9 | Data Package 10 - 100 t/a (Affiliates of Polyether Polyols Consortium members)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Identity Appearance State of the substance | Author: Currenta | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Identity Appearance State of the substance | Author: Currenta | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Determination of the melting point of Lupranol VP 9236 according to OECD 102 resp. EU A.1 | Author: LAUS GmbH | Year: 2007 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Determination of the melting point of Lupranol VP 9236 according to OECD 102 resp. EU A.1 | Author: LAUS GmbH | Year: 2007 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 102 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Determination of the boiling point of Lupranol VP 9236 according to OECD 103 resp. EU A.2 | Author: LAUS GmbH | Year: 2007 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Determination of the boiling point of Lupranol VP 9236 according to OECD 103 resp. EU A.2 | Author: LAUS GmbH | Year: 2007 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Physicochemical Properties of POLYETHER V 531 | Author: Currenta | Year: 2009 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Physicochemical Properties of POLYETHER V 531 | Author: Currenta | Year: 2009 | Guideline: 103 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Determination of the density of Lupranol VP 9236 according to OECD 109 resp. EU A.3 | Author: LAUS GmbH | Year: 2007 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Determination of the density of Lupranol VP 9236 according to OECD 109 resp. EU A.3 | Author: LAUS GmbH | Year: 2007 | Guideline: 109 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Waiver | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Determination of the Vapour Pressure of Lupranol VP 9236 according to OECD 104 resp. EU A.4 | Author: LAUS GmbH | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Determination of the Vapour Pressure of Lupranol VP 9236 according to OECD 104 resp. EU A.4 | Author: LAUS GmbH | Year: 2008 | Guideline: 104 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation of key physical-chemical properties for fifteen No-Longer-Polymer (NLP) polyether polyol substances | Author: West RJ | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Estimation of key physical-chemical properties for fifteen No-Longer-Polymer (NLP) polyether polyol substances | Author: West RJ | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the logPow of Lupranol VP 9236 using the HPLC method according to OECD 117 resp. EU A.8 | Author: LAUS GmbH | Year: 2008 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of the logPow of Lupranol VP 9236 using the HPLC method according to OECD 117 resp. EU A.8 | Author: LAUS GmbH | Year: 2008 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of the Partition Coefficient (Pow) by High Perfomance Liquid Chromatography (HPLC) method of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 117 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of the Partition Coefficient (Pow) by High Perfomance Liquid Chromatography (HPLC) method of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 117 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of the solubility in water of Lupranol VP 9236 according to OECD 105 resp. EU A.6 | Author: LAUS GmbH | Year: 2007 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of the solubility in water of Lupranol VP 9236 according to OECD 105 resp. EU A.6 | Author: LAUS GmbH | Year: 2007 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Water Solubility (Flask method) of POLYETHER V 531 at 20°C | Author: Currenta | Year: 2009 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Water Solubility (Flask method) of POLYETHER V 531 at 20°C | Author: Currenta | Year: 2009 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Guideline: 115 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Guideline: 115 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Physicochemical Properties of POLYETHER V531 | Author: Currenta | Year: 2009 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: R&D Report Polyol R3600 | Author: Perstorp | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.9 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Determination of the flash point of Lupranol VP 9236 according to EU A.9 | Author: LAUS GmbH | Year: 2007 | Guideline: EU Method A.9 (Flash-Point) | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: Determination of the flash point of Lupranol VP 9236 according to EU A.9 | Author: LAUS GmbH | Year: 2007 | Guideline: EU Method A.9 (Flash-Point) | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.15 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Determination of Safety-Relevant Data of POLYETHER V 531 | Author: Currenta | Year: 2009 | Guideline: A.12 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Determination of Safety-Relevant Data of POLYETHER V 531 | Author: Currenta | Year: 2009 | Guideline: A.12 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Flammability | Waiver | - |
| Phys-Chem | Oxidising properties | Robust Study Summary -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Oxidising properties | Right to refer to study -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.21 | Adequacy: other information | GLP: Y. | - |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Determination of Safety-Relevant Data of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: A.21 | Adequacy: other information | GLP: Y. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Determination of the Hydrolysis of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Hydrolysis | Right to refer to study -- Title: Determination of the Hydrolysis of Polyether V 531 | Author: Currenta | Year: 2009 | Guideline: 111 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: POLYETHER V 533 - Biodegradation | Author: Bayer Industry Services | Year: 2007 | Guideline: C.4-D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: POLYETHER V 533 - Biodegradation | Author: Bayer Industry Services | Year: 2007 | Guideline: C.4-D | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Adsorption/desorption | Waiver | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute Toxicity for Fish with POLYETHER V 533. | Author: Bayer Industry Services | Year: 2007 | Guideline: C.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute Toxicity for Fish with POLYETHER V 533. | Author: Bayer Industry Services | Year: 2007 | Guideline: C.1 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Polyether V 533 - Acute Daphnia Toxicity. | Author: Bayer Industry Services | Year: 2007 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Polyether V 533 - Acute Daphnia Toxicity. | Author: Bayer Industry Services | Year: 2007 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Polyether V 533 - Alga Growth Inhibition Test | Author: Bayer Industry Services | Year: 2007 | Guideline: equivalent to OECD TG 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Polyether V 533 - Alga Growth Inhibition Test | Author: Bayer Industry Services | Year: 2007 | Guideline: equivalent to OECD TG 201 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Polyether V 533 - Toxicity to Bacteria | Author: Bayer Industry Services | Year: 2007 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Polyether V 533 - Toxicity to Bacteria | Author: Bayer Industry Services | Year: 2007 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Grouping of additional NLP 'Polyols' and their Toxicokinetics Assessments | Author: Paul Illing Consultancy Services Ltd. and Marlin Consultancy | Year: 2010 | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Grouping of additional NLP 'Polyols' and their Toxicokinetics Assessments | Author: Paul Illing Consultancy Services Ltd. and Marlin Consultancy | Year: 2010 | Adequacy: weight of evidence. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity to rats of Polyol TP 30 | Author: Gardner JR | Year: 1988 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity to rats of Polyol TP 30 | Author: Gardner JR | Year: 1988 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Polyether V 533 Acute toxicity in the rat after oral administration | Author: Schüngel M | Year: 2007 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Polyether V 533 Acute toxicity in the rat after oral administration | Author: Schüngel M | Year: 2007 | Guideline: 423 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Waiver | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Polyether V 531 Acute toxicity in the rat after dermal application | Author: Gillissen U | Year: 2009 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Polyether V 531 Acute toxicity in the rat after dermal application | Author: Gillissen U | Year: 2009 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Evaluation of corrosive properties by using an artifical 3D-Skin model | Author: Vohr H-W | Year: 2007 | Guideline: B.40 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Evaluation of corrosive properties by using an artifical 3D-Skin model | Author: Vohr H-W | Year: 2007 | Guideline: B.40 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Polyether V 533: Acute skin irritation/corrosion on rabbits | Author: Gmelin C | Year: 2007 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Polyether V 533: Acute skin irritation/corrosion on rabbits | Author: Gmelin C | Year: 2007 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Irritant effects on rabbit skin of polyol TP30 | Author: Liggett MP | Year: 1988 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Irritant effects on rabbit skin of polyol TP30 | Author: Liggett MP | Year: 1988 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Waiver | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Polyether V 533: Acute eye irritation on rabbits | Author: Gmelin C | Year: 2009 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Polyether V 533: Acute eye irritation on rabbits | Author: Gmelin C | Year: 2009 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Irritant effects on the rabbit eye of Polyol TP30 | Author: Liggett | Year: 1988 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Irritant effects on the rabbit eye of Polyol TP30 | Author: Liggett | Year: 1988 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Waiver | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Polyether V 533: Local lymph node assay in mice (LLNA/IMDS) | Author: Vohr HW | Year: 2007 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Polyether V 533: Local lymph node assay in mice (LLNA/IMDS) | Author: Vohr HW | Year: 2007 | Guideline: 429 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Waiver | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Lupranol VP 9236 - Repeated dose 28-day oral toxicity study in Wistar rats; Administration by gavage) | Author: Kaspers U | Year: 2009 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Lupranol VP 9236 - Repeated dose 28-day oral toxicity study in Wistar rats; Administration by gavage) | Author: Kaspers U | Year: 2009 | Guideline: 407 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Waiver | - |
| Toxicological | Repeated dose toxicity: dermal | Waiver | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: In Vitro Chromosome Aberration Test with Chinese Hamster V79 Cells | Author: Nern M | Year: 2010 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro genetic toxicity | Right to refer to study -- Title: In Vitro Chromosome Aberration Test with Chinese Hamster V79 Cells | Author: Nern M | Year: 2010 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Polyol TP30: Ames Salmonella test Screening design | Author: Jensen | Year: 1995 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Polyol TP30: Ames Salmonella test Screening design | Author: Jensen | Year: 1995 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Polyether V 531: V79/HPRT-Test in vitro for the detection of induced forward mutations | Author: Entian G | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Polyether V 531: V79/HPRT-Test in vitro for the detection of induced forward mutations | Author: Entian G | Year: 2010 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Lupranol VP 9236 In vitro gene mutation test in L5178Y Mouse Lymphoma Cells (TK+/- locus assay microwell version) | Author: Schulz m & Landsiedel R | Year: 2008 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Lupranol VP 9236 In vitro gene mutation test in L5178Y Mouse Lymphoma Cells (TK+/- locus assay microwell version) | Author: Schulz m & Landsiedel R | Year: 2008 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Amendment No. 1 to the report - Lupranol VP 9236 In vitro gene mutation test in L5178Y Mouse Lymphoma Cells (TK+/- Locus Assay Microwell version) | Author: Schulz M | Year: 2009 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Amendment No. 1 to the report - Lupranol VP 9236 In vitro gene mutation test in L5178Y Mouse Lymphoma Cells (TK+/- Locus Assay Microwell version) | Author: Schulz M | Year: 2009 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Polyether V 533: Salmonella/Microsome Test Plate Incorporation and Preincubation Method | Author: Herbold B | Year: 2007 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Polyether V 533: Salmonella/Microsome Test Plate Incorporation and Preincubation Method | Author: Herbold B | Year: 2007 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Lupranol VP 9236 - Reproduction/Developmental Toxicity Screening Test in Wistar Rats - Oral Administration by gavage | Author: Buesen R | Year: 2010 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Lupranol VP 9236 - Reproduction/Developmental Toxicity Screening Test in Wistar Rats - Oral Administration by gavage | Author: Buesen R | Year: 2010 | Guideline: 421 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |