You are here: Home> Turkey>TR-REACH>CAS 123-31-9> CAS 123-31-9 | Data Package 10 - 100 t/a (Affiliates of Eastman)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol. 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: The Merck Index Fourteenth Edition | Author: Merck Index | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals (3rd ed.) | Author: Verschueren K. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of Data on Organic Compounds 3rd Edition Vol. I | Author: Lide DR Milne GWA (Ed.) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: SRC PhysProp-database | Author: Syracuse Research Corporation | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Hazardous Substances Databank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol. 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: The Merck Index Fourteenth Edition | Author: Merck Index | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals (3rd ed.) | Author: Verschueren K. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: PhysProp database | Author: Syracuse Research Corporation | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol. 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: The Merck Index Fourteenth Edition | Author: Merck Index | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Handbook of Data on Organic Compounds 3rd Edition Vol. I | Author: Lide DR Milne GWA (Ed.) | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: The Merck Index Fourteenth Edition | Author: Merck Index | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: PhysProp-database | Author: Syracuse Research Corporation | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals (3rd ed.) | Author: Verschueren K. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation Program Interface (EPI) Suite Version 4.00 | Author: Episuite | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimation Program Interface (EPI) Suite Version 4.00 | Author: Fraunhofer | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Estimating octanol-air partition coefficients with octanol-water partition coefficients and Henry's law constants. | Author: Meylan W.M., Howard P.H. | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Oxidation and reduction of hydroquinone and quinone from the standpoint of electromotive-force measurement | Author: Granger F.S. & Nelson J.M. | Year: 1921 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Library of Medicine | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: PhysProp-database | Author: Syracuse Research Corporation | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: The Merck Index Fourteenth Edition | Author: Merck Index | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Handbook of environmental data on organic chemicals (3rd ed.) | Author: Verschueren K. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Exploring QSAR. Hydrophobic Electronic and Steric Constants. ACS Professional Reference Book | Author: Hansch C. Leo A. & Hoekman D. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Calculation of Hydroquinone properties via EPISUITE 4.00 | Author: Fraunhofer | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Robust Study Summary -- Title: REACH Project: Granulometric characterization of Hydroquinone. | Author: Rhodia | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry)/Fibre length and diameter distribution | Right to refer to study -- Title: REACH Project: Granulometric characterization of Hydroquinone. | Author: Rhodia | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Solubility in organic solvents/fat solubility | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Flammability of solids on Hydroquinone CAS: 123-31-9 | Author: RHODIA | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Flammability of solids on Hydroquinone CAS: 123-31-9 | Author: RHODIA | Year: 2010 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Insitutes of Health | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Encyclopedia of Chemical Technology (3rd ed. Vol 13) | Author: Kirk-Othmer | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Hazardous Substances Data Bank | Author: National Institutes of Health | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: SAX Dangerous Properties of Industrial Materials (8th ed.) | Author: Lewis JR | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Hydroquinone: Acute and subchronic toxicity studies with emphasis on neurobehavioral and nephrotoxic effects. | Author: Topping D.C. et al. | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Hydroquinone: Acute and subchronic toxicity studies with emphasis on neurobehavioral and nephrotoxic effects. | Author: Topping D.C. et al. | Year: 2007 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Hydroquinone. Acute dermal toxicity study in the rat. (Amended final report) | Author: Sheppard K.P. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Hydroquinone. Acute dermal toxicity study in the rat. (Amended final report) | Author: Sheppard K.P. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Phenol (4 030 R.P.), hydroquinone (4 373 R.P.) et pyrocatechine (30 488 R.P.). Toxicite aigue chez le rat par voie percutanee de ces produits on solution aqueuses (in French). | Author: Julou L. Pasquet J. Mazuret M. | Year: 1973 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Phenol (4 030 R.P.), hydroquinone (4 373 R.P.) et pyrocatechine (30 488 R.P.). Toxicite aigue chez le rat par voie percutanee de ces produits on solution aqueuses (in French). | Author: Julou L. Pasquet J. Mazuret M. | Year: 1973 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Assessment of the skin sentisation potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation | Author: Kimber I. et al. | Year: 1998 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay. | Author: Lea L.J. et al. | Year: 1999 | Guideline: 429 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A comparison of three guinea-pig sensitization procedures for the detection of 19 reported human contact sensitizers. | Author: Goodwin B.F.J., Crevel R.W.R., and Johnson A.W. | Year: 1981 | Guideline: 406 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Experimental study on cross-reactivity of α-arbutin toward p-phenylenediamine and hydroquinone in guinea pigs | Author: To-o K. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Concomitant sensitization to hydroquinone and P-methoxyphenol in the guinea-pig; inhibitors in acrylic monomers. | Author: van der Walle H.B., Delbressine L.P.C., and Seutter E. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Investigation of the prohapten concept. | Author: Basketter D.A. Goodwin B.F.J. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Comparison of the Local Lymph Node Assay with the Guinea-Pig Maximization Test for the Detection of a Range of Contact Allergens. | Author: Basketter D.A. Goodwin B.F.J. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: The local lymph node assay: Developments and applications. | Author: Kimber I. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: A comparison of three guinea-pig sensitization procedures for the detection of 19 reported human contact sensitizers. | Author: Goodwin B.F.J., Crevel R.W.R., and Johnson A.W. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity test results for 250 chemicals. | Author: Haworth S. et al. | Year: 1983 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial mutagenicity test on Salmonella typhimurium according to B.N. Ames's technique with liver and kidney S9 fraction. Screening assay performed in micromethod using 4 strains, TA1537, TA98, TA100, and TA102 without repetition with the compound HQ. | Author: Watzinger M. | Year: 2007 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bacterial mutagenicity test on Salmonella typhimurium according to B.N. Ames's technique with liver and kidney S9 fraction. Screening assay performed in micromethod using 4 strains, TA1537, TA98, TA100, and TA102 without repetition with the compound HQ. | Author: Watzinger M. | Year: 2007 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro genetic toxicity | Robust Study Summary -- Title: Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone. | Author: Roza L., de Vogel N., and van Delft J.H.M. | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro genetic toxicity | Right to refer to study -- Title: Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone. | Author: Roza L., de Vogel N., and van Delft J.H.M. | Year: 2003 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosomal aberration test with hydroquinone in cultured human lymphocytes. | Author: de Vogel N. | Year: 2000 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Chromosomal aberration test with hydroquinone in cultured human lymphocytes. | Author: de Vogel N. | Year: 2000 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. | Author: Galloway S.M. et al. | Year: 1987 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Responses of the L1578Y tk+/tk- mouse lymphoma cell forward mutation assay. II. 18 coded chemicals. | Author: McGregor D.B. et al. | Year: 1988 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mechanisms of induction of chromosomal aberrations by hydroquinone in V79 cells. | Author: do Ceu Silva M. et al. | Year: 2003 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: GSTM1, GSTT1 and GSTP1 genotypes and the genotoxicity of hydroquinone in human lymphocytes. | Author: do Ceu Silva M. et al. | Year: 2004 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Role of oxygen radicals in the chromosomal loss and breakage induced by quinone-forming compounds hydroquinone and tert-butylhydroquinone. | Author: Dobo K.L. Eastmond D.A. | Year: 1994 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone. | Author: Doepker C.L. et al. | Year: 2000 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Characterisation of micronuclei induced in human lymphocytes by benzene metabolites. | Author: Yager J.W. et al. | Year: 1990 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Antimutagenicity study with hydroquinone in a chromosomal aberration test with cultured human lymphocytes. | Author: Van Delft J.H.M., and de Vogel N. | Year: 1997 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Antimutagenicity study with hydroquinone in a chromosomal aberration test with cultured human lymphocytes. | Author: Van Delft J.H.M., and de Vogel N. | Year: 1997 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro micronucleus test on mouse lymphoma cells (L5178Y) without metabolic activation and with metabolic activation by liver and kidney S9 fraction. Screening assay performed in micromethod with the compound hydroquinone. | Author: Watzinger M. | Year: 2007 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro micronucleus test on mouse lymphoma cells (L5178Y) without metabolic activation and with metabolic activation by liver and kidney S9 fraction. Screening assay performed in micromethod with the compound hydroquinone. | Author: Watzinger M. | Year: 2007 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: A method for in vitro culture of rat zymbal gland: Use in mechanistic studies of benzene carcinogenesis in combination with 32P-postlabeling. | Author: Reddy M.V. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: DNA adduction by phenol hydroquinone or benzoquinone in vitro but not in vivo: nuclease P1-enhanced 32P-postlabeling of adducts as labeled nucleoside biphosphates, dinucleotides and nucleosides monophosphates. | Author: Reddy M.V. et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Detection of DNA adducts in HL-60 cells treated with hydroquinone and p-benzoquinone by 32P-post labelling. | Author: Levay G., Pongracz K., and Bodel W.J. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Peroxidase activation of hydroquinone results in the formation of DNA adducts in HL-60 cells mouse bone marrow macrophages and human bone marrow. | Author: Levay G., Ross D., and Bodell W.J. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Benzene and its phenolic metabolites produce oxidative DNA damage in HL60 cells in vitro and in the bone marrow in vivo. | Author: Kolachana P. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Hydroquinone: Acute and subchronic toxicity studies with emphasis on neurobehavioral and nephrotoxic effects. | Author: Topping D.C. et al. | Year: 2007 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Hydroquinone. Acute oral toxicity study in the rat. (Final report) | Author: Sheppard K.P. | Year: 2002 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Hydroquinone. Acute oral toxicity study in the rat. (Final report) | Author: Sheppard K.P. | Year: 2002 | Guideline: 401 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Experimental studies on the toxicity of lithographic developer solution. | Author: Saito T., Takeichi S. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: The benzenediols: catechol resorcinol and hydroquinone: a review of the industrial toxicology and current industrial exposure limits. | Author: Flickinger C.W. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Hydroquinone: Acute and subchronic toxicity studies with emphasis on neurobehavioral and nephrotoxic effects. | Author: Topping D.C. et al. | Year: 2007 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Hydroquinone. Acute dermal toxicity study in the rat. (Amended final report) | Author: Sheppard K.P. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Hydroquinone. Acute dermal toxicity study in the rat. (Amended final report) | Author: Sheppard K.P. | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Phenol (4 030 R.P.) hydroquinone (4 373 R.P.) et pyrocatechine (30 488 R.P.). Toxicite aigue chez le rat par voie percutanee de ces produits on solution aqueuses (in French). | Author: Julou L., Pasquet J., and Mazuret M. | Year: 1973 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Phenol (4 030 R.P.) hydroquinone (4 373 R.P.) et pyrocatechine (30 488 R.P.). Toxicite aigue chez le rat par voie percutanee de ces produits on solution aqueuses (in French). | Author: Julou L., Pasquet J., and Mazuret M. | Year: 1973 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and disposition of hydroquinone in Fischer 344 rats after oral or dermal administration. | Author: English J.C., and Deisinger P.J. | Year: 2005 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolism and disposition of hydroquinone in Fischer 344 rats after oral or dermal administration. | Author: English J.C., and Deisinger P.J. | Year: 2005 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicokinetics studies with hydroquinone in male and female Fischer 344 rats. | Author: English J.C. et al. | Year: 1988 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Toxicokinetics studies with hydroquinone in male and female Fischer 344 rats. | Author: English J.C. et al. | Year: 1988 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicokinetics studies with hydroquinone (HQ) in Fischer 344 rats. | Author: English J.C. et al. | Year: 1991 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Development of a physiologically based pharmacokinetic model for hydroquinone. | Author: Corley R.A. et al. | Year: 2000 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Development of a physiologically based pharmacokinetic model for hydroquinone. | Author: Corley R.A. et al. | Year: 2000 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy. | Author: Hill B.A. et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: A physiologically based pharmacokinetic model for hydroquinone. | Author: Corley R.A., English J.C., and Morgott D.A. | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Development of a physiologically based pharmacokinetic model for hydroquinone. | Author: Corley R.A. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Development of a physiologically based pharmacokinetic model for hydroquinone. | Author: Corley R.A. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Tissue-to-plasma partition coefficients (PCS) for hydroquinone (HQ) in male Fischer and Sprague-Dawley rats. | Author: Hill T.S., Morgott D.A.,and English J.C. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The plasma protein binding of hydroquinone (HQ) in rats and humans. | Author: Fiorica L.A. et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolic Rate Constants for Hydroquinone in F344 Rat and Human Liver Isolated Hepatocytes: Application to a PBPK Model. | Author: Poet T.S. et al. | Year: 2004 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Comparison of the rates of interconversion of (L-Cystein-S-yl)-hydroquinone and (N-acetyl-L-cystein-S-yl)-hydroquinone in male and female Fischer 344 rat male Sprague-Dawley rat male B6C3F1 mouse and human kidneys. | Author: Barber E.D., English J.C. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Comparison of the rates of interconversion of (L-Cystein-S-yl)-hydroquinone and (N-acetyl-L-cystein-S-yl)-hydroquinone in male and female Fischer 344 rat male Sprague-Dawley rat male B6C3F1 mouse and human kidneys. | Author: Barber E.D., English J.C. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Hydroquinone PBPK model refinement and application to dermal exposure | Author: Poet T.S. et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Application of physiologically-based toxicokinetic modelling in oral-to-dermal extrapolation of threshold doses of cosmetic ingredients | Author: Gajewska M.A. et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Covalent protein adducts of hydroquinone in tissues from rats: identification and quantitation of sulfhydryl-bound forms. | Author: Boatman R.J. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Covalent protein adducts of hydroquinone in tissues from rats: quantitation of sulfhydryl-bound forms following single gavage or intraperitoneal administration or repetitive gavage administration. | Author: Boatman R.J. et al. | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Quantification of covalent protein adducts of hydroquinone in the blood and kidneys of rats. | Author: Boatman R.J. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Human exposure to naturally occurring hydroquinone. | Author: Deisinger P.J. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Human exposure to naturally occurring hydroquinone. | Author: Deisinger P.J., Hill T.S., and English J.C. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Bioavailability and metabolism of Hydroquinone after intratracheal instillation in male rats. | Author: Deisinger P.J. and English J.C. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism as a determinant of species susceptibility to 2,3,5- (triglutathion-S-yl)hydroquinone-mediated nephrotoxicity. The role of N- acetylation and N-deacetylation. | Author: Lau S.S., Kleiner H.E., and Monks T.J. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolic fate and disposition of [14C]hydroquinone given orally to Sprague-Dawley rats. | Author: Di Vincenzo et al. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Fate and disposition of [U-14C]hydroquinone in rats. | Author: Di Vincenzo et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Fate and disposition of [U-14C]hydroquinone in rats. | Author: Di Vincenzo et al. | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The metabolic fate of [U-14C] hydroquinone administered by gavage to male Fischer 344 rats. | Author: Lockhart H.B., Fox J.A., Di Vincenzo G.D. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: The metabolic fate of [U-14C] hydroquinone administered by gavage to male Fischer 344 rats. | Author: Lockhart H.B., Fox J.A., Di Vincenzo G.D. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The metabolic fate of [U-14C] hydroquinone administered by gavage to female Fischer 344 rats. | Author: Lockhart H.B. Fox J.A. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: The metabolic fate of [U-14C] hydroquinone administered by gavage to female Fischer 344 rats. | Author: Lockhart H.B. Fox J.A. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Blood elimination kinetics of [U-14C]hydroquinone administered by intragastric intubation intratracheal instillation or intravenous injection to male Fischer 344 rats. | Author: Fox J.A., English J.C., and Lockhart Jr. J.B. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Blood elimination kinetics of [U-14C]hydroquinone administered by intragastric intubation intratracheal instillation or intravenous injection to male Fischer 344 rats. | Author: Fox J.A., English J.C., and Lockhart Jr. J.B. | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Detection of hydroquinone in a poisoning case. | Author: Saito T. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In vitro conjugation of benzene metabolites by human liver: potential influence of interindividual variability on benzene toxicity. | Author: Seaton M.J., Schlosser P.M., and Medinsky M.A. | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetic interaction between benzene metabolites phenol and hydroquinone in B6C3F1 mice | Author: Legathe A., Hoener B.A., and Tozer T.N. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: Metabolism and disposition of hydroquinone in Fischer 344 rats after oral or dermal administration. | Author: English J.C. Deisinger P.J. | Year: 2005 | Guideline: 427 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice. | Author: Kari F.W. et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Subchronic oral toxicity study of hydroquinone in rats utilizing a functional observational battery and neuropathology to detect neurotoxicity. | Author: Topping D.C. | Year: 1988 | Guideline: 424 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: Subchronic oral toxicity study of hydroquinone in rats utilizing a functional observational battery and neuropathology to detect neurotoxicity. | Author: Topping D.C. | Year: 1988 | Guideline: 424 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Guideline: 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Relationship of hydroquinone-associated rat renal tumors with spontaneous chronic progressive nephropathy. | Author: Hard G.C. et al. | Year: 1997 | Guideline: 453 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicity and carcinogenicity of hydroquinone in F344/N rats and B6C3F1 mice. | Author: Kari F.W. et al. | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Toxicology and carcinogenesis studies of hydroquinone (CAS No. 123-31-9) in F344/N rats and B6C3F1 mice (gavage studies). | Author: NTP | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Corneal and conjunctival pigmentation among workers engaged in manufacture of hydroquinone. | Author: Anderson B. | Year: 1947 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Quinone vapors and their harmful effects. I. Corneal and conjunctival injury. | Author: Sterner J.H., Oglesby F.L., and Anderson B. | Year: 1947 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Quinone vapors and their harmful effects. II. Plant exposures associated with eye injuries. | Author: Oglesby F.L., Sterner J.H., & Anderson B. | Year: 1947 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Hydroquinone. | Author: Grant W.M. Schuman J.S. (Eds.) | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Corneal changes from quinone-hydroquinone exposure. | Author: Anderson B. Oglesby F. | Year: 1958 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Measurement of median lethal dose as a rapid indication of contaminant toxicity to fish. | Author: Hodson P.V., Dixon D.G., and Kaiser K.L.E. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Daphnia acute immobilization test (Daphnia magna) by hydroquinone. | Author: IDEA Consultants Inc. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Cyst-based ecotoxicological tests using Anostracans: Comparison of two species of Streptocephalus. | Author: Crisinel A. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Results of the harmful effects of selected water pollutants (anilines phenols aliphatic compounds) to Daphnia magna. | Author: Kühn R. et al. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Befunde der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna. | Author: Bringmann G. Kühn R. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Algal growth inhibition test (Pseudokirchneriella subcapitata) by hydroquinone. | Author: IDEA Consultants Inc. | Year: 2008 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Monitoring the toxicity of phenolic chemicals to activated sludge using a novel optical scanning respirometer. | Author: Chan C.M. et al. | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Comparison of the toxicity thresholds of water pollutants to bacteria algae and protozoa in the cell multiplication inhibition test. | Author: Bringmann G. Kühn R. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Testing for substances their toxicity threshold: Model organisms Microcystis (Diplocystis) aeruginosa and Scendesmus quadricauda. | Author: Bringmann G. Kühn R. | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation and bioaccumulation - Data of existing chemicals based on the CSCL Japan. | Author: MITI | Year: 1992 | Guideline: 301C | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: A correlation study of biodegradability determinations with various chemicals in various tests | Author: Gerike P. & Fischer W.K. | Year: 1979 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methanogenic degradation of four phenolic compounds | Author: Young L.Y. & Rivera M.D. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methanogenic degradation of hydroquinone in an anaerobic fixed-bed reactor | Author: Szewzyk U. & Schink B. | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: The biodegradation of hydroquinone | Author: Harbison K.G. & Belly R.T. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Adsorption coefficient for soils and sediment. In: Handbook of Chemical Property Estimation Methods. Lyman WJ Reehl WF & Rosenblatt DH (eds.) | Author: Lyman W.J. | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Schutz vor weiteren anthropogenen Organika-Eintraegen. In: Handbuch des Bodenschutzes. Bodenoekologie und -belastung. Vorbeugende und abwehrende Schutzmassnahmen. Blume HP (ed.) | Author: Litz N. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Calculation of Hydroquinone properties via EPISUITE 4.00 | Author: Fraunhofer | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Schutz vor weiteren anthropogenen Organika-Eintraegen. In: Handbuch des Bodenschutzes. Bodenoekologie und -belastung. Vorbeugende und abwehrende Schutzmassnahmen. Blume HP (ed.) | Author: Litz N. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |