You are here: Home> Turkey>TR-REACH>CAS 111-90-0> CAS 111-90-0 | Data Package 100 - 1000 t/a (Gattefosse studies)
| Study name | Short Description | Data Owner |
|---|---|---|
| Toxicological | Eye irritation | Right to refer to study -- Title: Transcutol. Ocular irritation and reversibility test on the rabbit | Author: Mercier O. | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Transcutol P -Bacterial reverse mutation test (plate incorporation) | Author: Aujoulat M. | Year: 1999 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute toxicity following a single oral administration (limit test) in the rat | Author: Cantor S. | Year: 1994 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | Gattefossé |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Plasma kinetics, absorption and tissue distribution of 14C-diethylene glycol monoethylether administered by intravenous and oral route to the male and female Sprague-Dawley rats and BDIX rats. | Author: Marsili-Guidicelli M.D. | Year: 2002 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolite determination of 14C-diethylene glycol monoethylenether administered by oral route to the male Sprague-Dawley rats | Author: Le Gal A. | Year: 2003 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | Gattefossé |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Metabolism study of diethylene glycol monoethylether administered by oral route to male Sprague-Dawley rats | Author: Le Gal A. | Year: 2003 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | Gattefossé |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: A 13-week oral (gavage) toxicity study of Transcutol HP in Beagle dogs | Author: Padgett E.L. | Year: 2007 | Guideline: 409 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: 28-Day repeat dose dermal toxicity study: rabbits | Author: Wnorowski G. | Year: 1995 | Guideline: 410 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Transcutol HP- Embryo toxicity study by the oral route (gavage) in the rat (Segment II) | Author: Rogissart A. | Year: 2002 | Guideline: 414 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | Gattefossé |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Reproduction/Development Toxicity Test: Fertility Study - Segment I | Author: Rogissart A. | Year: 2001 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | Gattefossé |