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| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Handbook of vapour pressures and heats of vapourisation of hydrocarbons and related compounds | Author: Zwolinski B.J and Wilhoit R.C | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Solubility in water of Paraffin Cycloparaffin Olefin Acetylene Cycloolefin and Aromatic Hydrocarbons | Author: McAuliffe C | Year: 1966 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics 89th ed. | Author: Lide et al (Ed) | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary dermal irritation study in the rabbit | Author: Trimmer G.W. | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary dermal irritation study in the rabbit | Author: Trimmer G.W. | Year: 1990 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.W. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Dermal sensitization test in the guinea pig | Author: Trimmer G.W. | Year: 1991 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: In vitro microbiological mutagenicity studies of hydrocarbon propellants | Author: Kirwin C.J. et al. | Year: 1980 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Detection of chemical mutagens by the dominant lethal assay in the mouse | Author: Epstein S.S. et al. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Acute oral toxicity study in rats. Cyclopentane. | Author: Pence D.H. | Year: 1982 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Acute oral toxicity study in rats. Cyclopentane. | Author: Pence D.H. | Year: 1982 | Guideline: 423 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Relative acute neurotoxicity of solvents: Isoeffective air concentrations of 48 compounds evaluated in rats and mice | Author: Frantik E. et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute inhalation toxicology of volatile hydrocarbons | Author: Swann Jr. H.E. et al. | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: The relative anaesthetic activity of the butanes and pentanes | Author: Stoughton R.; Lamson P. | Year: 1936 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism of ethane and pentane to carbon dioxide by the rat | Author: Daugherty M.S. et al. | Year: 1988 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Partition coefficients of some industrial aliphatic hydrocarbons (C5-C7) in blood and human tissues | Author: Perbellini L. et al. | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Uptake of 19 hydrocarbon vapors inhaled by F344 rats | Author: Dahl A.R. et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: The pharmacokinetics of pentane a by-product of lipid peroxidation | Author: Allerheiligen S.R.B. et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Quantitative evaluation to ethane and n-pentane as indicators of lipid peroxidation in vivo | Author: Filser J.G. et al. | Year: 1983 | Guideline: 417 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Experimental neurotoxicity and urinary metabolites of the C5-C7 aliphatic hydrocarbons used as glue solvents in shoe manufacture | Author: Frontali N. et al. | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicity evaluation of petroleum blending streams: Inhalation subchronic toxicity/neurotoxicity study of a light alkylate naphtha distillate in rats | Author: Schreiner C. | Year: 1998 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Repeated exposure inhalation study of pentane in rats | Author: Stadler J.C. et al. | Year: 2001 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Inhalation developmental toxicity and reproduction studies with cyclohexane | Author: Kreckmann K. et al. | Year: 2000 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Assessment in rats of the reproductive toxicity of gasoline from a gasoline vapor recovery unit | Author: McKee R. H. et al. | Year: 2000 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: One-generation reproductive toxicity study of 2-methylbutane in Sprague-Dawley rats | Author: Yu Wook-Joon et al. | Year: 2011 | Guideline: 415 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic toxicity of compounds that may be carried by ships (MARPOL 1973 Annex II). A progress report for 1986 | Author: Adema D.M.M and van den Bos Baker G.H | Year: 1987 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Predictions of the Aquatic Toxicity of High- Production Volume Chemicals Part A and B. | Author: Bol J Verhaar et al. | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to fish | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to fish | Right to refer to study -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Long-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Aquatic Toxicity Predictions Obtained Using the Petrotox Model for Hydrocarbons | Author: Concawe | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Bioaccumulation: aquatic/sediment | Robust Study Summary -- Title: Structure-toxicity relationships for industrial chemicals causing type (II)Narcosis Syndrome | Author: Veith GD and Broderius SJ. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Sediment toxicity | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Sediment toxicity | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath JA et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Sediment toxicity | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman AD et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except anthropods | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath JA et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except anthropods | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman AD et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to soil macro-organisms except anthropods | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial plants | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath JA et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial plants | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman AD et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial plants | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Extension and validation of the target lipid model for deriving predicted no-effect concentrations for soils and sediments | Author: Redman AD et al. | Year: 2014 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Refinement and validation of TLM-derived HC5 values. Independent review. | Author: McGrath JA et al. | Year: 2015 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Toxicity to terrestrial arthropods | Robust Study Summary -- Title: Technical basis for establishing sediment quality criteria for nonionic organic chemicals using equilibrium partitioning | Author: Di Toro D.M. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Mechanism and Structure | Author: Gould E | Year: 1959 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Chapter 7: Rate of Hydrolysis | Author: Harris J | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Hydrolysis | Author: Neely W | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ready biodegradability: 'manometric respirometry test' | Author: ExxonMobil Chemical | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ready biodegradability: 'manometric respirometry test' | Author: ExxonMobil Chemical | Year: 1996 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: QSARs for soil sorption. In: Overview of Structure-Activity Relationships for Environmental Endpoints. Hermens JLM (ed.) | Author: Sabljic A and Güsten H | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Environmental | Phototransformation in air | Robust Study Summary -- Title: Kinetics and mechanisms of gas-phase reactions with the hydroxyl radical with organic compounds under atmospheric conditions | Author: Atkinson R | Year: 1985 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Environmental | Phototransformation in water | Robust Study Summary -- Title: EPIWIN Estimation Program Interface for Windows version 3.04 | Author: US EPA - OPPT | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in water | Robust Study Summary -- Title: Chapter 8: Rate of Aqueous Photolysis. | Author: Harris JC | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in water | Robust Study Summary -- Title: Rates of Direct Photolysis in the Aqueous Environment | Author: Zepp RG and Cline DM. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in water | Robust Study Summary -- Title: Photoreactivity of Selected Aromatic Hydrocarbons in Water | Author: Zepp RG and Schlotzhauer PF. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in soil | Robust Study Summary -- Title: Rates of direct photolysis in the aqueous environment | Author: Zepp R. and Cline D | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in soil | Robust Study Summary -- Title: Chapter 8: Rate of Aqueous Photolysis | Author: Harris JC | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Phototransformation in soil | Robust Study Summary -- Title: Handbook of Property Estimation Methods for Chemicals | Author: Boethling R and Mackay D | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: Evaluation of primary irritation potential in humans (single 24-hour application) | Author: Rue B. and Plaza M.E. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Right to refer to study -- Title: Evaluation of primary irritation potential in humans (single 24-hour application) | Author: Rue B. and Plaza M.E. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: Odor intensity and symptoms produced by commercial propane butane pentane hexane and heptane vapor | Author: Patty F.A. and Yant W.P. | Year: 1929 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Neurotoxicity | Robust Study Summary -- Title: The relative anaesthetic activity of the butanes and pentanes | Author: Stoughton R. and Lamson P. | Year: 1936 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Neurotoxicity | Robust Study Summary -- Title: A comparative study on the neurotoxicity of n-pentane n-hexane and n-heptane in the rat | Author: Takeuchi Y. et al. | Year: 1980 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Specific investigations: other studies | Robust Study Summary -- Title: Behavioral toxicology of volatile organic solvents v. comparisons of the behavioral and neuroendocrine effects among n-alkanes | Author: Glowa J.R. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |