You are here: Home> Europe>UK-REACH>CAS 108-78-1> CAS 108-78-1 | Data Package 10 - 100 t/a (Pre-Brexit EU Registrants)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Estimation of the boiling temperature of melamine. | Author: EPA | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Melamine and Guanamines | Author: Ullmann; Chapter prepared by Crews GM et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Vapor Pressure of 2,4,6-Triamino-s-Triazine (Melamine) | Author: HIRT RC; STEGER JE; SIMARD GL | Year: 1960 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Estimation of the vapour pressure of melamine | Author: EPA | Year: 2009 | Guideline: 104 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Prüfbericht | Author: Redlich | Year: 2008 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Prüfbericht | Author: Redlich | Year: 2008 | Guideline: 105 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Melamine and Guanamines | Author: Ullmann; Chapter prepared by Crews GM et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Melamin LHH 01003 - Determination of the partition coefficient between octanol and water (log POW) by the shake flask method | Author: Junghans M | Year: 2009 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Melamin, LHH 01003 - Determination of the partition coefficient between octanol and water (log POW) by the shake flask method | Author: Junghans M | Year: 2009 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Guideline: 107 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Particle size distribution (Granulometry) | Robust Study Summary -- Title: Particle size distribution | Author: Synlab | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Particle size distribution (Granulometry) | Right to refer to study -- Title: Particle size distribution | Author: Synlab | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Explosive properties | Robust Study Summary -- Title: Explosionsschutz - Melamin- und Harnstoffstäube - Auswertung und Diskussion der Untersuchungsergebnisse (Protection against explosion - melamine and urea dust - Evaluation and discussion of results). | Author: Gresslehner G. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Explosive properties | Right to refer to study -- Title: Explosionsschutz - Melamin- und Harnstoffstäube - Auswertung und Diskussion der Untersuchungsergebnisse (Protection against explosion - melamine and urea dust - Evaluation and discussion of results). | Author: Gresslehner G. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: Determination of some physical-chemical properties of Melamine | Author: Reuse P and Holzschuh O | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Primary skin irritation / corrosion study with melamine in the rabbit | Author: Rijcken WRP | Year: 1995 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Primary skin irritation / corrosion study with melamine in the rabbit | Author: Rijcken WRP | Year: 1995 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: MELAMINE: Skin Sensitisation Study (Guinea Pig Maximisation Test) modified according to Maurer & Hess | Author: Weiss-Fuchs U | Year: 2010 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: MELAMINE: Skin Sensitisation Study (Guinea Pig Maximisation Test) modified according to Maurer & Hess | Author: Weiss-Fuchs U | Year: 2010 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: Evaluation of 108 chemicals. | Author: Galloway SM et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro cytogenetics - sister chromatid exchanges | Author: NTP | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Determination of the mutagenic potential of melamine using the plate incorporation method of the Ames Salmonella/microsome mutagenicity test | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Determination of the mutagenic potential of melamine using the plate incorporation method of the Ames Salmonella/microsome mutagenicity test | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity testing of melamine | Author: Mast RW; Friedman MA and Finch RA | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Rat hepatocyte primary culture / DNA repair test | Author: Naismith RW | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Rat hepatocyte primary culture / DNA repair test | Author: Naismith RW | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro sister chromatid exchange in Chinese hamster ovary cells. | Author: Sorg RM | Year: 1982 | Guideline: 479 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: In vitro sister chromatid exchange in Chinese hamster ovary cells. | Author: Sorg RM | Year: 1982 | Guideline: 479 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Determination of the DNA-damaging potential of melamine using the in vitro Chinese hamster ovary cell Sister Chromatid Exchange assay. | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Determination of the DNA-damaging potential of melamine using the in vitro Chinese hamster ovary cell Sister Chromatid Exchange assay. | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Mutagenicity testing of melamine | Author: Mast RW; Friedman MA and Finch RA | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity evaluation of melamine (2,4,6-triamine-s-triazine) | Author: Litton Bionetics Inc. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Mutagenicity evaluation of melamine (2,4,6-triamine-s-triazine) | Author: Litton Bionetics Inc. | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mouse lymphoma Study Details | Author: NTP | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 Coded Chemicals. | Author: McGregor DB et al. | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella: study summary. Salmonella: study details. | Author: NTP | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Salmonella mutagenicity test results for 250 chemicals. | Author: Haworth S et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Mutagenicity Characteristics of 255 Environmental Chemicals. | Author: Kubo T; Urano K; Utsumi H. | Year: 2002 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: Evaluation of 108 chemicals. | Author: Galloway SM et al. | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: In vitro cytogenetics - sister chromatid exchanges | Author: NTP | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Determination of the mutagenic potential of melamine using the CHO/HGPRT Chinese hamster ovary cell forward mutation assay. | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Right to refer to study -- Title: Determination of the mutagenic potential of melamine using the CHO/HGPRT Chinese hamster ovary cell forward mutation assay. | Author: Finch RA | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Mutagenicity testing of melamine | Author: Mast RW; Friedman MA and Finch RA | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Carcinogenesis Bioassay of Melamine (CAS No. 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) | Author: NTP | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Urolithiasis and Bladder Carcinogenicity of Melamine in Rodents | Author: Melnick RL et al. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Carcinogenesis Bioassay of Melamine (CAS No. 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) | Author: NTP | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Urolithiasis and Bladder Carcinogenicity of Melamine in Rodents | Author: Melnick RL et al. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Acute (4-hour) inhalation toxicity study with Melamine in rats | Author: Muijser H | Year: 1998 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Acute (4-hour) inhalation toxicity study with Melamine in rats | Author: Muijser H | Year: 1998 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Characterization of the disposition of melamine in female Sprague-Dawley rats using ultra-performance liquid chromatography-tandem mass spectrometry. | Author: Wu D et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetic study of melamine in rhesus monkey after a single oral administration of a tolerable daily intake dose. | Author: Liu G et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Toxicokinetic study of melamine in the presence and absence of cyanuric acid in rats. | Author: Pang J et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Intestinal Absorption and Urinary Excretion of Melamine in Male Wistar Rats | Author: Sugita T; Ishiwata H and Maekawa A | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Melamine in prenatal and postnatal organs in rats. | Author: Chu CY et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetics of melamine in pigs following intravenous administration. | Author: Baynes RE et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Quantification of melamine absorption distribution to tissues and excretion by sheep. | Author: Cruywagen CW et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Gestational and lactational transfer of melamine following gavage administration of a single dose to rats. | Author: Chan JY et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism disposition and excretion of [14C]Melamine in male Fischer 344 Rats | Author: Mast RW et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism of Hexamethylmelamine-Ring-14C in Rats and Man | Author: Worzalla JF et al. | Year: 1974 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Transplacental transfer of melamine. | Author: Partanen H et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: LC-MS/MS method for the determination of melamine in rat plasma: Toxicokinetic study in Sprague-Dawley rats | Author: Yang F et al. | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Pharmacokinetics of melamine and cyanuric acid and their combinations in F344 rats. | Author: Jacob CC et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Placental transfer of melamine and its effects on rat dams and fetuses | Author: Jingbin W et al. | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Carcinogenesis Bioassay of Melamine (CAS No. 108-78-1) in F344/N Rats and B6C3F1 Mice (Feed Study) | Author: NTP | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Chemical Risk Information Platform (CHRIP) | Author: NITE | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Acute and subacute toxicity to rainbow trout. | Author: Goodrich Lech J | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Acute and subacute toxicity to rainbow trout. | Author: Goodrich Lech J | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Evaluation of the renal effects of experimental feeding of melamine and cyanuric acid to fish and pigs | Author: Reimschuessel R et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: The Pathological Effects of Melamine and Cyanuric Acid in the Diet of Walking Catfish (Clarius batrachus). | Author: Pirarat N et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: The acute and chronic toxicity of melamine (2,4,6-triamino-triazine) to Daphnia magna | Author: Adema DMM | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: The acute and chronic toxicity of melamine (2,4,6-triamino-triazine) to Daphnia magna | Author: Adema DMM | Year: 1978 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Acute Toxicity of CT-338-87 to Daphnia Magna | Author: Frazier S | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Acute Toxicity of CT-338-87 to Daphnia Magna | Author: Frazier S | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: The effect of the product melamine on the growth of the green alga Scenedesmus pannonicus | Author: Oldersma H; Hanstveit AO | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: The effect of the product melamine on the growth of the green alga Scenedesmus pannonicus | Author: Oldersma H; Hanstveit AO | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Algal Growth Inhibition Test (OECD Method) using CT-338-87 | Author: Drozdowski D | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Algal Growth Inhibition Test (OECD Method) using CT-338-87 | Author: Drozdowski D | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Inhibition of nitrification - effects of selected organic compounds. | Author: Hockenbury MR; Grady CPL | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Melamine and Guanamines | Author: Ullmann; Chapter prepared by Crews GM et al. | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Hydrolysis | Robust Study Summary -- Title: Gmelins Handbuch der Anorganischen Chemie | Author: Gmelin | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Prüfung der biologischen Abbaubarkeit bzw. der Eliminierbarkeit von Melamin im Standardversuch nach Zahn-Wellens (Biodegradation of Melamine: Zahn-Wellens test) | Author: Taeger | Year: 1993 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Prüfung der biologischen Abbaubarkeit bzw. der Eliminierbarkeit von Melamin im Standardversuch nach Zahn-Wellens (Biodegradation of Melamine: Zahn-Wellens test) | Author: Taeger | Year: 1993 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Prüfung der biologischen Abbaubarkeit bzw. der Eliminierbarkeit von Melamin im Standardversuch nach Zahn Wellens (biodegradation of Melamine Zahn-Wellens test) | Author: Taeger | Year: 1992 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Prüfung der biologischen Abbaubarkeit bzw. der Eliminierbarkeit von Melamin im Standardversuch nach Zahn Wellens (biodegradation of Melamine Zahn-Wellens test) | Author: Taeger | Year: 1992 | Guideline: 302B | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Chemical Risk Information Platform (CHRIP) | Author: NITE | Year: 2010 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: The Scientific Aspects of the Chemical Substance Control Law in Japan | Author: Sasaki S | Year: 1978 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Technical Guidance Document on Risk Assessment. | Author: ECB | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |
| Environmental | Adsorption/desorption | Robust Study Summary -- Title: Estimation of the adsorption coefficient of melamine. | Author: EPA | Year: 2009 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. | - |