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CAS 108-10-1 | Data Package 10 - 100 t/a

Price: POA
All endpoints used in the EU REACH dossier and needed in the Turkey REACH dossier.
Note: some studies cannot be sold as part of this Data Package, and you will need to contact other organisations to get access to the following endpoints:
  • ACC - Ketones Panel : in vitro gene mutation study in bacteria (Ames); in vitro genetic toxicity; in vitro gene mutation study in mammalian cells
  • Lesser Ketones Manufacturing Association : Basic toxicokinetics

Product Features:

  • CAS 108-10-1

  • EC 203-550-1

  • 4-methylpentan-2-one

  • Methylisobutyl ketone

  • MiBK

Includes:

Study name Short Description Data Owner
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (89th Ed) | Author: Lide DR | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Appearance/physical state/colour Robust Study Summary -- Title: The Condensed Chemical Dictionary (10th Ed) | Author: Hawley G | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Melting point/freezing point Robust Study Summary -- Title: Directory of Solvents Blackie Academic & Professional | Author: B.P. Whim and P.G. Johnson | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Boiling point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Boiling point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Density Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: Directory of Solvents Blackie Academic & Professional | Author: B.P. Whim and P.G. Johnson | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Vapour pressure Robust Study Summary -- Title: The Condensed Chemical Dictionary (10th Ed) | Author: Hawley G | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Environmental | Henry's law constant Robust Study Summary -- Title: Henry's constant Law calculation | Author: Guidance on information requirements and chemical safety assessment (IR & CSA) Chapter 16 "Environmental exposure estimate" | Year: 2010 | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Phys-Chem | Water solubility Robust Study Summary -- Title: Determination of the Water Solubility of 4-methylpentan-2-one | Author: Mollandin G | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Water solubility Right to refer to study -- Title: Determination of the Water Solubility of 4-methylpentan-2-one | Author: Mollandin G | Year: 2010 | Guideline: 105 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Phys-Chem | Partition coefficient Robust Study Summary -- Title: Methyl Isobutyl Ketone: Determination of the n-Octanol/Water Partition Coefficient Using a Reverse-Phase HPLC Method (1983) | Author: Eadsforth CV | Year: 1983 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Partition coefficient Right to refer to study -- Title: Methyl Isobutyl Ketone: Determination of the n-Octanol/Water Partition Coefficient Using a Reverse-Phase HPLC Method (1983) | Author: Eadsforth CV | Year: 1983 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Phys-Chem | Flash point Robust Study Summary -- Title: Directory of Solvents Blackie Academic & Professional | Author: B.P. Whim and P.G. Johnson | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Flash point Robust Study Summary -- Title: The Merck Index: An Encyclopedia of Chemicals Drugs and Biologicals (14th Edition) | Author: O'Neil MJ | Year: 2006 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Flash point Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: The Condensed Chemical Dictionary (10th Ed) | Author: Hawley G | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Phys-Chem | Auto-ignition temperature Robust Study Summary -- Title: Directory of Solvents Blackie Academic & Professional | Author: B.P. Whim and P.G. Johnson | Year: 1996 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence. -
Phys-Chem | Flammability Robust Study Summary -- Title: CRC Handbook of Chemistry and Physics (81st Ed) | Author: Lide DR | Year: 2000 | Klimisch score: 2 - Reliable with restrictions | Adequacy: other information | GLP: N. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: METHYL ISO BUTYL KETONE : SKIN IRRITATION IN THE RABBIT | Author: Gardner JR | Year: 1996 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: METHYL ISO BUTYL KETONE : SKIN IRRITATION IN THE RABBIT | Author: Gardner JR | Year: 1996 | Guideline: 404 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Skin irritation / corrosion Robust Study Summary -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Klimisch score: 4 - Not assignable. -
Toxicological | Skin irritation / corrosion Right to refer to study -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Klimisch score: 4 - Not assignable. -
Toxicological | Eye irritation Robust Study Summary -- Title: METHYL ISO BUTYL KETONE : EYE IRRITATION IN THE RABBIT | Author: Gardner JR | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Right to refer to study -- Title: METHYL ISO BUTYL KETONE : EYE IRRITATION IN THE RABBIT | Author: Gardner JR | Year: 1996 | Guideline: 405 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Eye irritation Robust Study Summary -- Title: Methyl isobutyl ketone EEC study, BCO-P assay no. 30 | Author: Giroux J | Year: 1992 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Eye irritation Right to refer to study -- Title: Methyl isobutyl ketone EEC study, BCO-P assay no. 30 | Author: Giroux J | Year: 1992 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Eye irritation Robust Study Summary -- Title: Interlaboratory assessment of the bovine corneal opacity and permeability (BCOP) assay | Author: Gautheron P. et al. | Year: 1994 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Eye irritation Robust Study Summary -- Title: Technical report no. 48. Eye irritation : reference chemical data bank | Author: ECETOC | Year: 1992 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Eye irritation Robust Study Summary -- Title: Eye irritation: Reference chemicals data bank | Author: Bagley D.M. et al. | Year: 1992 | Guideline: 405 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Skin sensitisation Robust Study Summary -- Title: Prüfung auf hautsensibilisierende Wirkung am Meerschweinchen von Methylisobutylketon | Author: Mürmann P | Year: 1989 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | Skin sensitisation Right to refer to study -- Title: Prüfung auf hautsensibilisierende Wirkung am Meerschweinchen von Methylisobutylketon | Author: Mürmann P | Year: 1989 | Guideline: 406 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Right to refer to study -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks TM, Meyer AL, and Hutson DH | Year: 1988 | Guideline: 471 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity studies on ketone solvents: methyl ethyl ketone, methyl isobutyl ketone and isophorone | Author: O'Donoghue J.L. et al. | Year: 1988 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | in vitro gene mutation study in bacteria (Ames) Robust Study Summary -- Title: Mutagenicity studies on ketone solvents: methyl ethyl ketone, methyl isobutyl ketone and isophorone | Author: O'Donoghue J.L. et al. | Year: 1988 | Guideline: 482 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 480 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in mammalian cells Right to refer to study -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 480 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks TM, Meyer AL, and Hutson DH | Year: 1988 | Guideline: 480 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | in vitro gene mutation study in mammalian cells Robust Study Summary -- Title: Mutagenicity studies on ketone solvents: methyl ethyl ketone, methyl isobutyl ketone and isophorone | Author: O'Donoghue J.L. et al. | Year: 1988 | Guideline: 476 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Right to refer to study -- Title: Toxicity Studies with chemical solvents: short-term in vitro tests for genotoxic activity with methyl isobutyl ketone | Author: Thorpe E | Year: 1982 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | in vitro cytogenicity study in mammalian cells (CA) Robust Study Summary -- Title: The genetic toxicology of some hydrocarbon and oxygenated solvents | Author: Brooks T.M., Meyer A.L. and Hutson D.H. | Year: 1988 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: oral Robust Study Summary -- Title: RANGE-FINDING TOXICITY DATA: LIST IV | Author: Smyth H.F., Carpenter C.P. and Weil C.S. | Year: 1951 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Year: 1976 | Klimisch score: 4 - Not assignable. -
Toxicological | Dermal absorption Right to refer to study -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Year: 1976 | Klimisch score: 4 - Not assignable. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: RANGE-FINDING TOXICITY DATA: LIST IV | Author: Smyth H.F., Carpenter C.P. and Weil C.S. | Year: 1951 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Acute response of guinea pigs to inhalation of methyl isobutyl ketone | Author: Specht H | Year: 1938 | Klimisch score: 4 - Not assignable. -
Toxicological | Acute toxicity: inhalation Robust Study Summary -- Title: Acute response of guinea pigs to the inhalation of ketone vapors | Author: Specht H. et al. | Year: 1940 | Klimisch score: 4 - Not assignable. -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: METHYL ISO BUTYL KETONE : ACUTE DERMAL TOXICITY IN THE RAT | Author: Gardner JR | Year: 1996 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: METHYL ISO BUTYL KETONE : ACUTE DERMAL TOXICITY IN THE RAT | Author: Gardner JR | Year: 1996 | Guideline: 402 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Acute toxicity: dermal Robust Study Summary -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Year: 1976 | Klimisch score: 4 - Not assignable. -
Toxicological | Acute toxicity: dermal Right to refer to study -- Title: Toxicity and Irritation Assay Results of Some Food, Drug or Cosmetic Product Chemicals | Author: UCC | Year: 1976 | Klimisch score: 4 - Not assignable. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Tissue concentrations of methyl isobutyl ketone methyl nbutyl ketone and their metabolites after oral and inhalation exposure | Author: Duguay AB and Plaa GL | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Plasma concentrations in methyl isobutyl ketone-potentiated experimental cholestasis after inhalation or oral administration | Author: Duguay AB and Plaa GL | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Characterization of the Metabolites of Methyl n-Butyl Ketone Methyl iso-Butyl Ketone and Methyl Ethyl Ketone in Guinea Pig and their Clearance | Author: DiVincenzo GD, Kaplan CJ, and Dedinas J | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Metabolic fate of methyl n-butyl ketone methyl isobutyl ketone and their metabolites in mice | Author: Granvil CP, Aharkawi M, and Plaa GL | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study.
Read-Across (4-hydroxy-4 methyl-2-pentanone (HMP); 4-methyl-2-pentanol (4-MPOL MIBC); methyl isobutyl ketone (MIBK))
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Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Mechanism of Transport and Distribution of Organic Solvents in Blood | Author: Lam C. et al. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: Comparative metabolism of methyl isobutyl carbinol and methyl isobutyl ketone in male rats | Author: Gingell R. et al. | Year: 2003 | Guideline: 417 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: The metabolism of methyl isobutyl ketone and its biological monitoring: Part 1. Qualitative and quantitative studies of methyl isobutyl ketone exhaled from the lungs and excreted in the urine and the metabolites in the urine of rats injected with MIBK | Author: Hirota N | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Basic toxicokinetics Robust Study Summary -- Title: The Transplacental Migration and Accumulation in Blood of Volatile Organic constituents | Author: Dowty BJ, Laseter JL and Storer J | Year: 1976 | Klimisch score: 2 - Reliable with restrictions. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Dermal Absorption Potential of Industrial Chemicals: Criteria for Skin Notation | Author: Fiserova-Bergerova V, Pierce JT, and Droz PO | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. -
Toxicological | Dermal absorption Robust Study Summary -- Title: Percutaneous uptake and kinetics of methyl isobutyl ketone (MIBK) in the guinea pig | Author: Hjelm E.W. et al. | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: 14-week inhalation toxicity study of methyl isobutyl ketone | Author: Phillips R.D. et al. | Year: 1987 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: N. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Effect of 90-day continuous exposure to methylisobutylketone on dogs monkeys and rats | Author: Mac Ewen JD, Vernot EH and Haun CC | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Continuous exposure of animals to methyl isobutyl ketone | Author: Vernot EH, MacEwen JD, and Harris ES | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: Pathological lesions caused by methylisobutylketone | Author: MacKenzie WF | Year: 1971 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Toxicological | Repeated dose toxicity: inhalation Robust Study Summary -- Title: 14-week inhalation toxicity study of methyl isobutyl ketone | Author: Phillips RD et al. | Year: 1987 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Acute Toxicity of 4-methylpentan-2-one to Zebrafish (Danio rerio) in a 96-hour Static Limit-Test in Closed Vessel Design | Author: Kuhl R & Deierling T | Year: 2010 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Acute Toxicity of 4-methylpentan-2-one to Zebrafish (Danio rerio) in a 96-hour Static Limit-Test in Closed Vessel Design | Author: Kuhl R & Deierling T | Year: 2010 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Ergebnisse der Untersuchung von 200 chemischen Verbindungen auf aktue Fischtoxizität mit den Goldenorfentest | Author: Juhnke I, Lüdemann D | Year: 1978 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Short-term toxicity to fish Robust Study Summary -- Title: Determination of Acute toxicity to Fish of Shell Chemials | Author: Bridié AL, Winter M, Wolff CJM | Year: 1973 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Short-term toxicity to fish Right to refer to study -- Title: Determination of Acute toxicity to Fish of Shell Chemials | Author: Bridié AL, Winter M, Wolff CJM | Year: 1973 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Acute Toxicity of 4-methylpentan-2-one to Daphnia magna in a Static 48-hour Immobilisation Limit-Test in Closed Vessel Design | Author: Kuhl R & Wydra V | Year: 2009 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Right to refer to study -- Title: Acute Toxicity of 4-methylpentan-2-one to Daphnia magna in a Static 48-hour Immobilisation Limit-Test in Closed Vessel Design | Author: Kuhl R & Wydra V | Year: 2009 | Guideline: 202 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Befunde der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna | Author: Bringmann G and Kühn R | Year: 1977 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Short-term toxicity to aquatic invertebrates Robust Study Summary -- Title: Ergebnisse der Schadwirkung wassergefährdender Stoffe gegen Daphnia magna in einem weiterentwickel standardisierten Testverfahren | Author: Bringmann G and Kühn R | Year: 1981 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. I. Bakterienfressende Flagellaten (Modellorganismus: Entosiphon sulcatum Stein) | Author: Bringmann G. | Year: 1978 | Guideline: 209 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. II. Bakterienfressende Ciliaten | Author: Bringmann G. and Kühn R. | Year: 1980 | Guideline: 209 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Bestimmung der biologischen Schadwirkung wassergefährdender Stoffe gegen Protozoen. III. Saprozoische Flagellaten | Author: Bringmann G., Kühn R. and Winter A. | Year: 1980 | Guideline: 209 | Klimisch score: 4 - Not assignable | Adequacy: weight of evidence | GLP: N. -
Eco-Tox | Toxicity to microorganisms Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Bakterien (Pseudomonas putida) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G and Kühn R | Year: 1977 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Blaualgen (Microcystis aeruginosa) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G and Kühn R | Year: 1978 | Klimisch score: 3 - Not reliable. -
Eco-Tox | Toxicity to aquatic algae and cyanobacteria Robust Study Summary -- Title: Grenzwerte der Schadwirkung wassergefährdender Stoffe gegen Bakterien (Pseudomonas putida) und Grünalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest | Author: Bringmann G and Kühn R | Year: 1977 | Klimisch score: 3 - Not reliable. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Ready Biodegradability of Methylisobutylcetone in a Manometric Respirometry Test | Author: Feil N | Year: 2009 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Right to refer to study -- Title: Ready Biodegradability of Methylisobutylcetone in a Manometric Respirometry Test | Author: Feil N | Year: 2009 | Guideline: 301F | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan | Author: Chemicals Inspection & Testing Institute Japan | Year: 1992 | Guideline: 301C | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. -
Environmental | Biodegradation in water: screening tests Robust Study Summary -- Title: BOD and COD of Some Petrochemicals | Author: Bridié AL, Wolff CJM, Winter M | Year: 1979 | Klimisch score: 4 - Not assignable | Adequacy: other information | GLP: N. -
Environmental | Adsorption/desorption Robust Study Summary -- Title: Non hydrophobic equation | Author: Guidance on information requirements and chemical safety assessment (IR & CSA) Chapter 16 "Environmental exposure estimate" | Year: 2010 | Klimisch score: 2 - Reliable with restrictions | Adequacy: weight of evidence | GLP: N. -
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