You are here: Home> Turkey>TR-REACH>CAS 107-98-2> CAS 107-98-2 | Data Package > 1000 t/a (Affiliates of Member 0947)
| Study name | Short Description | Data Owner |
|---|---|---|
| Phys-Chem | Appearance/physical state/colour | Robust Study Summary -- Title: No information | Author: The Dow Chemical Company | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Appearance/physical state/colour | Right to refer to study -- Title: No information | Author: The Dow Chemical Company | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Melting point/freezing point | Robust Study Summary -- Title: Solvents | Author: Dieter Stoye | Year: 1993 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Derivatives of Glycols | Author: V. K. Rowe M. A. Wolf | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Boiling point | Robust Study Summary -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Boiling point | Right to refer to study -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Guideline: 103 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Right to refer to study -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Density | Robust Study Summary -- Title: Derivatives of Glycols | Author: V. K. Rowe M. A. Wolf | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Right to refer to study -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Vapour pressure | Robust Study Summary -- Title: Derivatives of Glycols | Author: V. K. Rowe M. A. Wolf | Year: 1982 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Determination of the surface tension of an aqueous solution of propylene glycol methyl ether | Author: NOTOX B.V. | Year: 2010 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Determination of the surface tension of an aqueous solution of propylene glycol methyl ether | Author: NOTOX B.V. | Year: 2010 | Guideline: 115 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Phys-Chem | Surface tension | Robust Study Summary -- Title: Dowanol-P Propylene Glycol Ether Physical Data Base | Author: The Dow Chemical Company | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Surface tension | Right to refer to study -- Title: Dowanol-P Propylene Glycol Ether Physical Data Base | Author: The Dow Chemical Company | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Water solubility | Robust Study Summary -- Title: Environmental Assessment for Glycol Ethers | Author: The Dow Chemical Company | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Water solubility | Right to refer to study -- Title: Environmental Assessment for Glycol Ethers | Author: The Dow Chemical Company | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: An examination of the physical properties fate ecotoxicity and potential environmental risks for a series of propylene glycol ethers | Author: Charles A. Staples John W. Davis | Year: 2002 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri, Daphnia magna, and Selenastrum capricornutum) and n-octanol/water partition coefficient. | Author: Shell Research Limited | Year: 1986 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri, Daphnia magna, and Selenastrum capricornutum) and n-octanol/water partition coefficient. | Author: Shell Research Limited | Year: 1986 | Guideline: 117 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Phys-Chem | Partition coefficient | Robust Study Summary -- Title: Environmental assessment for glycol ethers | Author: The Dow Chemical Company | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Partition coefficient | Right to refer to study -- Title: Environmental assessment for glycol ethers | Author: The Dow Chemical Company | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Right to refer to study -- Title: Density, Viscosity, and Vapor Pressure Data for DOWANOL PnB Glycol Ether Product and DOWANOL PM Glycol Ether | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Viscosity | Robust Study Summary -- Title: Solvents | Author: Dieter Stoye | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flammability | Robust Study Summary -- Title: No information | Author: The Dow Chemical Company | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flammability | Right to refer to study -- Title: No information | Author: The Dow Chemical Company | Year: 1987 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: Solvents | Author: Dieter Stoye | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Phys-Chem | Flash point | Robust Study Summary -- Title: No information | Author: The Dow Chemical Company | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Flash point | Right to refer to study -- Title: No information | Author: The Dow Chemical Company | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Robust Study Summary -- Title: No information | Author: The Dow Chemical Company | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Phys-Chem | Auto-ignition temperature | Right to refer to study -- Title: No information | Author: The Dow Chemical Company | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Experimental study of cutaneous tolerance to glycol ethers | Author: Zissu.D | Year: 1995 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth et al. (1962) | Year: 1962 | Guideline: 404 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Robust Study Summary -- Title: unpublished report No. 78/186; May 28 1979 | Author: BASF Aktiengesellschaft | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin irritation / corrosion | Right to refer to study -- Title: unpublished report No. 78/186; May 28 1979 | Author: BASF Aktiengesellschaft | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Industrial Hygiene Orientating Investigation | Author: BASF AG Department of toxicology | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Industrial Hygiene Orientating Investigation | Author: BASF AG Department of toxicology | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth et al. (1962) | Year: 1962 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: No information | Author: BASF AG Abt. Toxikologie. | Year: 1979 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: No information | Author: BASF AG Abt. Toxikologie. | Year: 1979 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Klimisch score: 3 - Not reliable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Right to refer to study -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Eye irritation | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe V.K. McCollister D.D. Spencer H.C. et al. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Propylene glycol monomethyl ether: Skin sensitization potential in the guinea pig | Author: The Dow Chemical Company | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Propylene glycol monomethyl ether: Skin sensitization potential in the guinea pig | Author: The Dow Chemical Company | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Skin sensitisation | Robust Study Summary -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Skin sensitisation | Right to refer to study -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Genotoxic and/or epigenetic effects of some glycol ethers: results of different short-term tests | Author: Elias Z. et al. (1996) | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Metaphase analysis of Chinese hamster ovary (CHO) cells treated with DOWANOL™ PM | Author: The Dow Chemical Company | Year: 1983 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Right to refer to study -- Title: Metaphase analysis of Chinese hamster ovary (CHO) cells treated with DOWANOL™ PM | Author: The Dow Chemical Company | Year: 1983 | Guideline: 473 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | other mutagenicity information | Robust Study Summary -- Title: Evaluation of DOWANOL™ PM in the rat hepatocyte unscheduled DNA synthesis assay | Author: The Dow Chemical Company | Year: 1983 | Guideline: 482 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | other mutagenicity information | Right to refer to study -- Title: Evaluation of DOWANOL™ PM in the rat hepatocyte unscheduled DNA synthesis assay | Author: The Dow Chemical Company | Year: 1983 | Guideline: 482 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | other mutagenicity information | Robust Study Summary -- Title: Genotoxic and/or epigenetic effects of some glycol ethers: results of different short-term tests | Author: Elias Z. et al. | Year: 1996 | Guideline: 479 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Genotoxic and/or epigenetic effects of some glycol ethers: results of different short-term tests | Author: Elias Z. et al. (1996) | Year: 1996 | Guideline: 476 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bacterial mutagenicity tests on Dowanol PM | Author: The Dow Chemical Company | Year: 1983 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bacterial mutagenicity tests on Dowanol PM | Author: The Dow Chemical Company | Year: 1983 | Guideline: 471 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | in vitro gene mutation study in mammalian cells | Robust Study Summary -- Title: Genotoxic and/or Epigenetic Effects of some Glycol Ethers: Results of different short-term tests | Author: Elias Z. et al. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Robust Study Summary -- Title: Bericht über die Prüfung von Lösungsmittel PM (ZNT Substanz-Nr.: 82/322) im Ames test (Standard plate test with Salmonella typhimurium) | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro gene mutation study in bacteria (Ames) | Right to refer to study -- Title: Bericht über die Prüfung von Lösungsmittel PM (ZNT Substanz-Nr.: 82/322) im Ames test (Standard plate test with Salmonella typhimurium) | Author: BASF AG | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | in vitro cytogenicity study in mammalian cells (CA) | Robust Study Summary -- Title: Genotoxic and/or epigenetic effects of some glycol ethers: results of different short-term tests | Author: Elias Z. et al. (1996) | Year: 1996 | Guideline: 473 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Genetic toxicity in vivo | Robust Study Summary -- Title: Genotoxic and/or Epigenetic Effects of some Glycol Ethers: Results of different short-term tests | Author: Elias Z. et al. | Year: 1996 | Guideline: 474 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe V.K. McCollister D.D. Spencer H.C. et al. | Year: 1954 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The single dose toxicity of some glycols and derivatives | Author: Smyth et al. (1941) | Year: 1941 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: No information | Author: BASF AB Abt. Toxikologie. | Year: 1964 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: No information | Author: BASF AB Abt. Toxikologie. | Year: 1964 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: The Pharmacology of the Mono Methyl Ethers of Mono- Di- and Tripropylene Glycol in the dog with observations on the auricular fibrillation produced by these compounds | Author: Shideman F.E. and Procita L. | Year: 1951 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: unpublished data (78/186) July 19 1979 | Author: BASF AG | Year: 1979 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: unpublished data (78/186) July 19 1979 | Author: BASF AG | Year: 1979 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range Finding Tests on UCAR Solvent LM (Monomethyl Ether of Propylene Glycol) | Author: Union Carbide Corporation | Year: 1961 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: Range Finding Tests on UCAR Solvent LM (Monomethyl Ether of Propylene Glycol) | Author: Union Carbide Corporation | Year: 1961 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth et al. | Year: 1962 | Guideline: 401 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: No information | Author: BASF AG | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Right to refer to study -- Title: No information | Author: BASF AG | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: oral | Robust Study Summary -- Title: Zur Toxizität des Propzlenglykol-monomethylaethers | Author: Stenger E.G. Aeppli L. Macheiner J. Müller D. Trokan J. | Year: 1972 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: unpublished data (78/186) | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: unpublished data (78/186) | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Dowanol* PM Glycol Ether: An Acute Vapor Inhalation Study in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Dowanol* PM Glycol Ether: An Acute Vapor Inhalation Study in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe V.K. McCollister D.D. Spencer H.C. et al. | Year: 1954 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Range Finding Tests on UCAR Solvent LM | Author: Union Carbide Chemicals/The Dow Chemical Company | Year: 1961 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth et al. (1962) | Year: 1962 | Guideline: 403 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: Dowanol* PM Glycol Ether: An Acute Vapor Inhalation Study in B6C3F1 mice. | Author: The Dow Chemical Company | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: Dowanol* PM Glycol Ether: An Acute Vapor Inhalation Study in B6C3F1 mice. | Author: The Dow Chemical Company | Year: 1991 | Guideline: 403 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: inhalation | Robust Study Summary -- Title: No information | Author: BASF AB Abt. Toxikologie | Year: 1964 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: inhalation | Right to refer to study -- Title: No information | Author: BASF AB Abt. Toxikologie | Year: 1964 | Klimisch score: 4 - Not assignable | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Toxicology of Industrial Chemicals: The Acute Oral and Percutaneous Toxicity, Skin and Eye Irritancy, and Skin Sensitizing Potential of Methyl Proxitol | Author: Shell Research Limited | Year: 1985 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Range Finding Tests on UCAR Solvent LM (Monomethyl Ether of Propylene Glycol) | Author: Union Carbide Corporation | Year: 1961 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Range Finding Tests on UCAR Solvent LM (Monomethyl Ether of Propylene Glycol) | Author: Union Carbide Corporation | Year: 1961 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Range-Finding Toxicity Data: List VI | Author: Smyth et al. | Year: 1962 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: Toxicological Properties and industrial Handling Hazards of new DowTherm 209 Formulation containing 98% Dowanol PM (Propylene Glycol Methyl Ether) | Author: The Dow Chemical Company | Year: 1966 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Right to refer to study -- Title: The Toxicology of Propylene Glycole Methyl Ether (Dowanol 33B), Dipropylene Glycole Methyl Ether (Dowanol 50B), and TriPropylene Glycole Methyl Ether (Dowanol 62B) | Author: The Dow Chemical Company | Year: 1953 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: dermal | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe V.K. McCollister D.D. Spencer H.C. et al. | Year: 1954 | Guideline: 402 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Effect of age on toxicokinetics among human volunteers exposed to propylene glycol methyl ether (PGME) | Author: Hopf N et al. | Year: 2012 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether (PGME) and Propylene Glycol Monomethyl Ether Acetate (PGMEA) - A: In vitro hydrolysis of PGMEA in rat and human blood and liver homogenate B: Kinetics of PGME and PGMEA following intravenous administration to Fischer 344 Rats | Author: The Dow Chemical Company | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether (PGME) and Propylene Glycol Monomethyl Ether Acetate (PGMEA) - A: In vitro hydrolysis of PGMEA in rat and human blood and liver homogenate B: Kinetics of PGME and PGMEA following intravenous administration to Fischer 344 Rats | Author: The Dow Chemical Company | Year: 2001 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In-vitro Metabolism of Propylene Glycol Ethers | Author: The Dow Chemical Company | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In-vitro Metabolism of Propylene Glycol Ethers | Author: The Dow Chemical Company | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Comparative Metabolism and Disposition of Ethylene Glycol Monomethyl Ether (EGME) and Propylene Glycol Monomethyl Ether (PGME) in male rats | Author: The Dow Chemical Company | Year: 1982 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Comparative Metabolism and Disposition of Ethylene Glycol Monomethyl Ether and Propylene Glycol Monomethyl Ether in male rats | Author: Miller et al. | Year: 1983 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Metabolism and Disposition of Propylene Glycol Monomethyl Ether (PGME) Beta Isomer in Male Rats | Author: Miller et al. | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Nonlinear Kinetics of Inhaled Propylene Glycol Monometyl Ether in Fischer 344 Rats following single and repeated exposures | Author: The Dow Chemical Company | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Nonlinear Kinetics of Inhaled Propylene Glycol Monometyl Ether in Fischer 344 Rats following single and repeated exposures | Author: The Dow Chemical Company | Year: 1986 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Nonlinear Kinetics of Inhaled Propylene Glycol Monometyl Ether in Fischer 344 Rats following single and repeated exposures | Author: Morgott D.A. and Nolan R.J. | Year: 1987 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Blood Pharmcokinetics of Propylene Glycol Methyl Ether (PGME) and Propylene Glycol Methyl Ether Acetate (PGMEA) in male F-344 rats after dermal application | Author: Chemical Manufacturers Association | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: Blood Pharmcokinetics of Propylene Glycol Methyl Ether (PGME) and Propylene Glycol Methyl Ether Acetate (PGMEA) in male F-344 rats after dermal application | Author: Chemical Manufacturers Association | Year: 1999 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Determination of 1-methoxy-2-propanol and its metabolite 1,2-propanediol in rat and mouse plasma by gas chromatography. | Author: Ferrala NF et al. | Year: 1994 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: Development of a physiologically based pharmacokinetic model for propylene glycol monomethyl ether and its acetate in rats and humans | Author: Corley et al | Year: 2005 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In Vitro Metabolism of Propylene Glycol Monomethyl Ether isomers, Dipropylene Glycol Monomethyl Ether, and Tripropylene Glycol Monomethyl Ether in rat, rabbit, and human liver hepatocytes | Author: The Dow Chemical Company | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In Vitro Metabolism of Propylene Glycol Monomethyl Ether isomers, Dipropylene Glycol Monomethyl Ether, and Tripropylene Glycol Monomethyl Ether in rat, rabbit, and human liver hepatocytes | Author: The Dow Chemical Company | Year: 2004 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Basic toxicokinetics | Robust Study Summary -- Title: In-vitro Studies to evaluate Glycol Ethers as substrates for Alcohol Dehydrogenase | Author: The Dow Chemical Company | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Basic toxicokinetics | Right to refer to study -- Title: In-vitro Studies to evaluate Glycol Ethers as substrates for Alcohol Dehydrogenase | Author: The Dow Chemical Company | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: Absorption of some Glycol Ethers through Human Skin in-vitro | Author: Dugard P.H. et al | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Dermal absorption | Robust Study Summary -- Title: Percutaneous absorption of thirty-eight organic solvents in vitro using pig skin | Author: Linda Schenk et al. | Year: 2018 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: The Toxicology Of Propylene Glycol Methyl Ether, Dipropylene Glycol Methyl Ether, and Tripropylene Glycol Methyl Ether | Author: The Dow Chemical Company | Year: 1953 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: The Toxicology Of Propylene Glycol Methyl Ether, Dipropylene Glycol Methyl Ether, and Tripropylene Glycol Methyl Ether | Author: The Dow Chemical Company | Year: 1953 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Toxicology Of Mono Di Tripropylene Glycol Methyl Ethers | Author: Rowe et al. (1954) | Year: 1954 | Guideline: 407 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: No information | Author: BASF AG Abt. Toxikologie | Year: 1965 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Right to refer to study -- Title: No information | Author: BASF AG Abt. Toxikologie | Year: 1965 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: oral | Robust Study Summary -- Title: Zur Toxizität des Propylenglykol-monomethylaethers | Author: Stenger E.G. Aeppli L. Macheiner J. Müller D. Trokan J. | Year: 1972 | Guideline: 408 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: DOWANOL PM: Results of a 9 Day Vapor Inhalation Study with Rat and Mice | Author: The Dow Chemical Company | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: DOWANOL PM: Results of a 9 Day Vapor Inhalation Study with Rat and Mice | Author: The Dow Chemical Company | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Comparative Short-Term Inhalation Toxicity of Ethylene Glycol Monomethyl Ether and Propylene Glycol Monomethyl Ether in Rats and Mice | Author: Miller et al. | Year: 1981 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The evaluation of hepatic cellular proliferation and P450 induction in B6C3F1 mice and Fischer 344 rats exposed to Propylene glycol monomethyl ether. | Author: The Dow Chemical Company | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The evaluation of hepatic cellular proliferation and P450 induction in B6C3F1 mice and Fischer 344 rats exposed to Propylene glycol monomethyl ether. | Author: The Dow Chemical Company | Year: 1992 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Adaptive Metabolic and Pathologic Changes following Chronic Inhalation of Propylene Glycol Monomethyl Ether in rats and mice | Author: Corley R.A. et al | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: DOWANOL PM: Results of a 9 Day Vapor Inhalation Study With Rat and Mice | Author: The Dow Chemical Company | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: DOWANOL PM: Results of a 9 Day Vapor Inhalation Study With Rat and Mice | Author: The Dow Chemical Company | Year: 1980 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe et al. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether: A 2-year vapor inhalation chronic toxicity/oncogenicity study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction in B6C3F1 Mice | Author: The Dow Chemical Company | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene glycol monomethyl ether: A 2-year vapor inhalation chronic toxicity/oncogenicity study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction in B6C3F1 Mice | Author: The Dow Chemical Company | Year: 1998 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether (PGME): Inhalation toxicity carcinogenicity and mode of action in Fischer 344 rats B6C3F1 mice. | Author: Spencer P.J. Crissman J.W. et al. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether: A 13-week vapor inhalation study to evaluate hepatic and renal cellular proliferation P450 enzyme induction and protein droplet nephropathy in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene glycol monomethyl ether: A 13-week vapor inhalation study to evaluate hepatic and renal cellular proliferation P450 enzyme induction and protein droplet nephropathy in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: 2-Week Vapor Inhalation Study in Rats and Mice | Author: The Dow Chemical Company | Year: 1983 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether: 2-Week Vapor Inhalation Study in Rats and Mice | Author: The Dow Chemical Company | Year: 1983 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: A 13 Week Inhalation Toxicity Study In Rats and Rabbits | Author: The Dow Chemical Company | Year: 1982 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether: A 13 Week Inhalation Toxicity Study In Rats and Rabbits | Author: The Dow Chemical Company | Year: 1982 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: A 13 Week Inhalation Toxicity Study In Rats and Rabbits | Author: The Dow Chemical Company | Year: 1982 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether: A 13 Week Inhalation Toxicity Study In Rats and Rabbits | Author: The Dow Chemical Company | Year: 1982 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: A 13 Week Inhalation Toxicity Study In Rats and Rabbits | Author: Landry et al. (1983) | Year: 1983 | Guideline: 413 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe et al. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether:2-Week vapor Inhalation study in rats and mice | Author: The Dow Chemical Company | Year: 1983 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene glycol monomethyl ether:2-Week vapor Inhalation study in rats and mice | Author: The Dow Chemical Company | Year: 1983 | Guideline: 412 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Effect of Repeated Inhalation of Vapors of Industrial Solvents on Animal Bahavior | Author: Goldberg et al. | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether: A 13-week vapor inhalation study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction in B6C3F1 Mice | Author: The Dow Chemical Company | Year: 1996 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: Propylene glycol monomethyl ether: A 13-week vapor inhalation study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction in B6C3F1 Mice | Author: The Dow Chemical Company | Year: 1996 | Guideline: 413 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: A 2-year vapor inhalation chronic toxicity/oncogenicity study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction and protein droplet nephropathy in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1998 | Guideline: 453 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: A 2-year vapor inhalation chronic toxicity/oncogenicity study and evaluation of hepatic and renal cellular proliferation P450 enzyme induction and protein droplet nephropathy in Fischer 344 rats | Author: The Dow Chemical Company | Year: 1998 | Guideline: 453 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Propylene glycol monomethyl ether (PGME): Inhalation toxicity carcinogenicity and mode of action in Fischer 344 rats B6C3F1 mice | Author: Spencer P.J. Crissman J.W. et al | Year: 2002 | Guideline: 453 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Toxicology of Mono- Di- and Tri-Propylene Glycol Methyl Ethers | Author: Rowe et al. | Year: 1954 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: Comparative Aspects of the Reproductive Toxicology by Inhalation in rats of Ethylene Glycol Monomethyl Ether and Propylene Glycol Monomethyl Ether | Author: Doe et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Robust Study Summary -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: inhalation | Right to refer to study -- Title: The Toxicology of Propylene Glycol Methyl Ether (DOWANOL 33B), Dipropylene Glycol Methyl Ether (DOWANOL 50B), and Tripropylene Glycol Methyl Ether (DOWANOL 62B) | Author: The Dow Chemical Company | Year: 1953 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether (PGME): 21- Day Dermal Study In New Zealand White Rabbits | Author: The Dow Chemical Company | Year: 1984 | Guideline: 410 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether (PGME): 21- Day Dermal Study In New Zealand White Rabbits | Author: The Dow Chemical Company | Year: 1984 | Guideline: 410 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: The Toxicology of Propylene Glycol Methyl Ether Dipropylene Glycol Methyl Ether and Tripropylene Glycol Methyl Ether | Author: The Dow Chemical Company | Year: 1953 | Guideline: 411 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: The Toxicology of Propylene Glycol Methyl Ether Dipropylene Glycol Methyl Ether and Tripropylene Glycol Methyl Ether | Author: The Dow Chemical Company | Year: 1953 | Guideline: 411 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Toxicology of Mono Di Tripropylene Glycol Methyl Ethers | Author: Rowe et al. | Year: 1954 | Guideline: 411 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Robust Study Summary -- Title: Chronic Skin Absorption of Propylene Glycol Methyl Ether (33B) and Dipropylene Glycol Methyl Ether (50B) in Rabbits | Author: The Dow Chemical Company | Year: 1949 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Repeated dose toxicity: dermal | Right to refer to study -- Title: Chronic Skin Absorption of Propylene Glycol Methyl Ether (33B) and Dipropylene Glycol Methyl Ether (50B) in Rabbits | Author: The Dow Chemical Company | Year: 1949 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Zur Toxizität des Propylenglykol-monomethylaethers | Author: Stenger E.G. et al. | Year: 1972 | Klimisch score: 4 - Not assignable | Adequacy: supporting study. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: Inhalation Teratology Study in rats and rabbits (first species) | Author: The Dow Chemical Company | Year: 1983 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether: Inhalation Teratology Study in rats and rabbits (first species) | Author: The Dow Chemical Company | Year: 1983 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: Inhalation Teratology Study in rats and rabbits (second species) | Author: The Dow Chemical Company | Year: 1983 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Right to refer to study -- Title: Propylene Glycol Monomethyl Ether: Inhalation Teratology Study in rats and rabbits (second species) | Author: The Dow Chemical Company | Year: 1983 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Teratologic Evaluation of Inhaled Propylene Glycol Monomethyl Ether in rats and rabbits | Author: Hanley et al. | Year: 1984 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Developmental toxicity/teratogenicity | Robust Study Summary -- Title: Ethylene Glycol Monomethyl Ether (EGME) and Propylene Glycol Monomethyl Ether (PGME): Inhalation Fertility and Teratogenicity Studies in rats mice and rabbits | Author: Hanley et al. | Year: 1984 | Guideline: 414 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Propylene glycol monomethyl ether: Two-generation inhalation reproduction study in Sprague-Dawley rats. | Author: The Dow Chemical Company | Year: 1997 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Right to refer to study -- Title: Propylene glycol monomethyl ether: Two-generation inhalation reproduction study in Sprague-Dawley rats. | Author: The Dow Chemical Company | Year: 1997 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Assessment of adult and neonatal reprouctive parameters in Sprague-Dawley rats exposed to propylene glycol monomehtyl ehter vapors for two generations. | Author: Carney E.W. et al. | Year: 1999 | Guideline: 416 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Comparative Aspects of the reproductive toxicology by inhalation in rats of EGME and PGME | Author: Doe et al. | Year: 1983 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Further studies on the Toxicology of the Glycol Ethers with Emphasis on Rapid Screening and Hazard Assessment | Author: Doe. J.E. | Year: 1984 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Propylene Glycol Monomethyl Ether: Reproduction and Fertility Assessment in CD-1 Mice when administered in drinking water | Author: National Toxicology Program | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Propylene Glycol Methyl Ether | Author: Chapin RE and Sloane RA | Year: 1986 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Toxicity to reproduction | Robust Study Summary -- Title: Reproductive Assessment by Continuous Breeding: Evolving Study Design and Summaries of Ninety Studies | Author: Robert E. Chapin and Richard A. Sloane | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Dermal Absorption of Vapours | Author: Jones K. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Human volunteer study with propylene glycol monomethyl ether: Potential eye irritation during vapour exposure. | Author: Emmen HH et al. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Right to refer to study -- Title: Human volunteer study with propylene glycol monomethyl ether: Potential eye irritation during vapour exposure. | Author: Emmen HH et al. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: Acute effects of an exposure to 100 ppm 1-methoxypropanol-2 on the upper airways of human subjects | Author: Muttray A et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: Sex differences in urinary levels of several biological indicators of exposure: A human volunteer study. | Author: Tomicic C et al. | Year: 2011 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Direct observations: clinical cases, poisoning incidents and other | Robust Study Summary -- Title: No information | Author: Stewart et al. | Year: 1970 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Specific investigations: other studies | Robust Study Summary -- Title: Early stress response of human nasal respiratory epithelia after exposure to 1-methoxypropanol-2. | Author: Brieger J et al. | Year: 2008 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Higher prevalence of breathlessness in elderly exposed to indoor aldehydes and VOCs in a representative sample of French dwellings. | Author: Bentayeb M et al. | Year: 2013 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Propylene glycol monomethyl ether (PGME) occupational exposure - 1. Biomonitoring by analysis of PGME in urine. | Author: Devanthéry A. Dentan A. Berode M. and Droz P.-O. | Year: 2000 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Exposure-related observations in humans: other data | Robust Study Summary -- Title: Propylene glycol monomethyl ether (PGME) occupational exposure. 3. Exposure of human volunteers. | Author: Devanthéry A. Berode M. and Droz P.O. | Year: 2002 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Report on the study of the acute toxicity of 1-Methoxypropanol-2 on the Golden orfe (Leuciscus idus L. golden variety) | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Report on the study of the acute toxicity of 1-Methoxypropanol-2 on the Golden orfe (Leuciscus idus L. golden variety) | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Acute Toxicity to Marine / Brackish-Water Fish | Author: The Dow Chemical Company | Year: 2014 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Acute Toxicity to Marine / Brackish-Water Fish | Author: The Dow Chemical Company | Year: 2014 | Guideline: 203 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri, Daphnia magna, and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri, Daphnia magna, and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 203 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study. | - |
| Eco-Tox | Short-term toxicity to fish | Robust Study Summary -- Title: Evaluation of the toxicity of DOWANOL* PM to representative aquatic organisms | Author: The Dow Chemical Company | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to fish | Right to refer to study -- Title: Evaluation of the toxicity of DOWANOL* PM to representative aquatic organisms | Author: The Dow Chemical Company | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Acute Toxicity to Acartia tonsa | Author: The Dow Chemical Company | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Acute Toxicity to Acartia tonsa | Author: The Dow Chemical Company | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Evaluation of the toxicity of DOWANOL™ PM to representative aquatic organisms | Author: The Dow Chemical Company | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Evaluation of the toxicity of DOWANOL™ PM to representative aquatic organisms | Author: The Dow Chemical Company | Year: 1981 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Bestimmung der akuten Wirkung von 1-Methoxypropanol- 2 gegenueber dem Wasserfloh Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Bestimmung der akuten Wirkung von 1-Methoxypropanol- 2 gegenueber dem Wasserfloh Daphnia magna Straus | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Robust Study Summary -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Short-term toxicity to aquatic invertebrates | Right to refer to study -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 202 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Algentest | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Algentest | Author: BASF AG | Year: 1989 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: DOWANOL PM glycol ether: Evaluation of the toxicity to the green alga Selenestrum capricornutum printz | Author: The Dow Chemical Company | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: DOWANOL PM glycol ether: Evaluation of the toxicity to the green alga Selenestrum capricornutum printz | Author: The Dow Chemical Company | Year: 1988 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Porpylene glycol methyl ether (synonym: Dowanol PM): marine algal growth inhibition test | Author: Sacker D | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Porpylene glycol methyl ether (synonym: Dowanol PM): marine algal growth inhibition test | Author: Sacker D | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Robust Study Summary -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to aquatic algae and cyanobacteria | Right to refer to study -- Title: Methyl proxitol: acute toxicity (Salmo gairdneri Daphnia magna and Selenastrum capricornutum) and n-octanol/water partition coefficient | Author: Shell Research Limited | Year: 1986 | Guideline: 201 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Evaluation of the OECD 'Activated sludge respiration inhibition test' for assessment of the potential impact of chemicals on wastewater treatment systems. | Author: The Dow Chemical Company | Year: 1984 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Evaluation of the OECD 'Activated sludge respiration inhibition test' for assessment of the potential impact of chemicals on wastewater treatment systems. | Author: The Dow Chemical Company | Year: 1984 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Evaluation of the OECD Activated Sludge Respiration inhibition test | Author: Klecka GM Landi LP and Bodner KM | Year: 1985 | Guideline: 209 | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Eco-Tox | Toxicity to microorganisms | Robust Study Summary -- Title: Wachstumshemmtest in Anlehnung an Bringmann-Kuehn | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Eco-Tox | Toxicity to microorganisms | Right to refer to study -- Title: Wachstumshemmtest in Anlehnung an Bringmann-Kuehn | Author: BASF AG | Year: 1988 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methyl Proxitol - An assessment of ready biodegradability. | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301B | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Methyl Proxitol - An assessment of ready biodegradability. | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301B | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Assessment of Biodegradability in Sea Water; Closed Bottle Test | Author: Roulstone | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Propylene glycol methyl ether (synonym: Dowanol™ PM): Assessment of Biodegradability in Sea Water; Closed Bottle Test | Author: Roulstone | Year: 2014 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Methyl Proxitol - An assessment of ready biodegradability. | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301D | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Methyl Proxitol - An assessment of ready biodegradability. | Author: Shell Research Ltd. | Year: 1985 | Guideline: 301D | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Biodegradation of Propylene Glycol, Propylene Glycol Methyl Ether, Dipropylene Glycol Methyl Ether, and Antwerp wastewater constituents with activated plaquemine WWTP Sludge | Author: Toxicology and Environmental Research and Consulting | Year: 2012 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Biodegradation of Propylene Glycol, Propylene Glycol Methyl Ether, Dipropylene Glycol Methyl Ether, and Antwerp wastewater constituents with activated plaquemine WWTP Sludge | Author: Toxicology and Environmental Research and Consulting | Year: 2012 | Guideline: 301F | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Determination of the Biodegradability of 1-Methoxypropanol-2 in the Modified OECD Screening-Test | Author: BASF AG | Year: 1985 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Determination of the Biodegradability of 1-Methoxypropanol-2 in the Modified OECD Screening-Test | Author: BASF AG | Year: 1985 | Guideline: 301E | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Ultimate Biochemical Oxygen Demand (BOD) Test. | Author: ARCO Chemical Company Newtown Square Pennsylvania. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Ultimate Biochemical Oxygen Demand (BOD) Test. | Author: ARCO Chemical Company Newtown Square Pennsylvania. | Year: 1996 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Evaluation of the anaerobic biodegradation of 1-methoxy-2-propanol (DOWANOL PM) and dipropylene glycol monomethyl ether (DOWANOL DPM) in anaerobic digester sludge. | Author: The Dow Chemical Company | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Evaluation of the anaerobic biodegradation of 1-methoxy-2-propanol (DOWANOL PM) and dipropylene glycol monomethyl ether (DOWANOL DPM) in anaerobic digester sludge. | Author: The Dow Chemical Company | Year: 1998 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: Environmental assessment for glycol ethers. | Author: The Dow Chemical Company. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: Environmental assessment for glycol ethers. | Author: The Dow Chemical Company. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in water: screening tests | Robust Study Summary -- Title: DOWANOL PM - Assessment of ready biodegradability modified OECD screening test. | Author: The Dow Chemical Company | Year: 1994 | Guideline: 301E | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in water: screening tests | Right to refer to study -- Title: DOWANOL PM - Assessment of ready biodegradability modified OECD screening test. | Author: The Dow Chemical Company | Year: 1994 | Guideline: 301E | Klimisch score: 1 - Reliable without restriction | Adequacy: key study | GLP: Y. | - |
| Environmental | Distribution modelling | Robust Study Summary -- Title: Environmental assessment for glycol ethers. | Author: The Dow Chemical Company. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Distribution modelling | Right to refer to study -- Title: Environmental assessment for glycol ethers. | Author: The Dow Chemical Company. | Year: 1990 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Distribution modelling | Robust Study Summary -- Title: Biodegradation of Glycol ethers in soil. | Author: Stanley J. Gonsior and Robert J. West | Year: 1995 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Phototransformation in air | Robust Study Summary -- Title: Simulated Atmospheric Photodecomposition Rates of Methylene Chloride, 1,1,1 Trichloroethane, Trichloroethylene, Tetrachloroethylene, and other Compounds | Author: Wendell L et al. | Year: 1976 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Environmental | Biodegradation in soil | Robust Study Summary -- Title: Biodegradation of DOWANOL PM, DOWANOL PPH, and DOWANOL PMA glycol ethers in soil. | Author: The Dow Chemical Company | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Environmental | Biodegradation in soil | Right to refer to study -- Title: Biodegradation of DOWANOL PM, DOWANOL PPH, and DOWANOL PMA glycol ethers in soil. | Author: The Dow Chemical Company | Year: 1991 | Klimisch score: 2 - Reliable with restrictions | Adequacy: key study | GLP: Y. | - |
| Toxicological | Health surveillance data | Robust Study Summary -- Title: Dermal Absorption of Vapours | Author: Jones K. | Year: 1997 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study. | - |
| Toxicological | Health surveillance data | Robust Study Summary -- Title: Human volunteer study with propylene glycol monomethyl ether: Potential eye irritation during vapour exposure. | Author: Emmen HH et al. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Health surveillance data | Right to refer to study -- Title: Human volunteer study with propylene glycol monomethyl ether: Potential eye irritation during vapour exposure. | Author: Emmen HH et al. | Year: 1997 | Klimisch score: 1 - Reliable without restriction | Adequacy: supporting study. | - |
| Toxicological | Acute toxicity: other routes | Robust Study Summary -- Title: Zur Toxizitat des Propylenglykol-monomethylaethers | Author: Stenger et al. | Year: 1972 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: other routes | Robust Study Summary -- Title: Abt. Toxikologie. | Author: Unpublished report of BASF AG | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: other routes | Right to refer to study -- Title: Abt. Toxikologie. | Author: Unpublished report of BASF AG | Year: 1964 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: other routes | Robust Study Summary -- Title: Abt. Toxikologie | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Toxicological | Acute toxicity: other routes | Right to refer to study -- Title: Abt. Toxikologie | Author: BASF AG | Year: 1979 | Klimisch score: 2 - Reliable with restrictions | Adequacy: supporting study | GLP: N. | - |
| Phys-Chem | Robust Studies Summaries | Robust Study Summary -- Title: Robust Studies Summaries package for all studies (1-10 tpa). | - |
| Phys-Chem | Robust Studies Summaries | Robust Study Summary -- Title: Robust Studies Summaries package for all studies (10-100 tpa). | - |
| Phys-Chem | Robust Studies Summaries | Robust Study Summary -- Title: Robust Studies Summaries package for all studies (100-1000 tpa). | - |
| Phys-Chem | Robust Studies Summaries | Robust Study Summary -- Title: Robust Studies Summaries package for all studies (>1000 tpa). | - |
| Chemical Safety Report | Title: Chemical Safety Report. | - |